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Condition: Bipolar

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Total 381 results found since Jan 2013.

MRI spot sign
A 47-year-old woman presented with fever and acute right subdural hematoma. Her neurologic examination was normal, but she experienced persistent severe headache and repeat CT showed increasing mass effect. Lumbar puncture was deferred for risk of herniation. MRI was performed to evaluate for septations, abnormal enhancement, or other atypical features that would suggest an alternative diagnosis such as subdural empyema. An area of active contrast extravasation was seen on MRI (figure) and corresponded, at surgical evacuation, to a small bleeding artery that was ablated with bipolar cautery. Despite extensive evaluation, n...
Source: Nature Clinical Practice - December 8, 2014 Category: Neurology Authors: Cutsforth-Gregory, J. K., Black, D. F., Hoffman, E. M., Datar, S. V., Wijdicks, E. F. Tags: MRI, All Cerebrovascular disease/Stroke, Critical care Cases Source Type: research

What 'Empire' Got Right (And Wrong) About Music Therapy
Perhaps one of the most stirring and sympathetic characters in Fox’s hit show “Empire" is Andre, who suffers from Bipolar disorder. In case you’ve been living under a rock for the past three months and haven’t watched the hottest TV show of 2015, here’s a quick recap of Andre’s situation: the oldest son of a music conglomerate CEO vies for power over the company he helped build, but between all the pressure (and betrayal, and violence, and lack of love and support), as well as his attempts to keep a lid on his emotions, Andre eventually flushes his meds down the toilet, precipitating a mental breakdown and entr...
Source: Healthy Living - The Huffington Post - March 19, 2015 Category: Consumer Health News Source Type: news

No such thing as baby brain, study argues
Conclusion The researchers conclude that although the pregnant women reported memory problems, these did not show up on their tests. However, this does not take into account their pre-pregnancy ability. The women may have performed better before they got pregnant, which is why they are now reporting memory problems. None of these women were tested before they got pregnant, which is the major limitation of the study. The researchers say that because there were a similar number of students in each group, the women in the control group was a good enough representation of how the pregnant women would have performed pre-pregna...
Source: NHS News Feed - April 8, 2015 Category: Consumer Health News Tags: Mental health Neurology Pregnancy/child Source Type: news

Biphasic monopolar electrical stimulation induces rapid and directed galvanotaxis in adult subependymal neural precursors
Conclusion: We purport that balanced biphasic stimulation represents a clinically-viable technique for mobilizing NPCs that may be integrated into strategies for promoting endogenous neurorepair.
Source: BioMed Central - April 12, 2015 Category: Journals (General) Authors: Robart Babona-PiliposAlex Pritchard-OhMilos R PopovicCindi M Morshead Source Type: research

Automated removal of spurious intermediate cerebral blood flow volumes improves image quality among older patients: A clinical arterial spin labeling investigation
ConclusionThis study developed an automated head motion threshold‐free procedure to improve the detection of CBF in GM. The improvement in CBF image quality was larger when considering older participants. J. Magn. Reson. Imaging 2015.
Source: Journal of Magnetic Resonance Imaging - April 15, 2015 Category: Radiology Authors: Zahra Shirzadi, David E. Crane, Andrew D. Robertson, Pejman J. Maralani, Richard I. Aviv, Michael A. Chappell, Benjamin I. Goldstein, Sandra E. Black, Bradley J. MacIntosh Tags: Original Research Source Type: research

Highly Efficient Glutathione Peroxidase and Peroxiredoxin Mimetics Protect Mammalian Cells against Oxidative Damage.
Abstract Novel isoselenazoles with high glutathione peroxidase (GPx) and peroxiredoxin (Prx) activities provide remarkable cytoprotection to human cells, mainly by exhibiting antioxidant activities in the presence of cellular thiols. The cytotoxicity of the isoselenazoles is found to be significantly lower than that of ebselen, which is being clinically evaluated by several groups for the treatment of reperfusion injuries and stroke, hearing loss, and bipolar disorder. The compounds reported in this paper have the potential to be used as therapeutic agents for disorders mediated by reactive oxygen species. PM...
Source: Angewandte Chemie - June 1, 2015 Category: Chemistry Authors: Bhowmick D, Srivastava S, D'Silva P, Mugesh G Tags: Angew Chem Int Ed Engl Source Type: research

Population norms for the EQ-5D index scores using Singapore preference weights
Conclusions These findings support the use of the Singapore preference weights for EQ-5D valuations when measuring health-related quality of life and comparing the health burden of psychiatric and chronic physical conditions among adults in Singapore.
Source: Quality of Life Research - June 1, 2015 Category: Health Management Source Type: research

Surgical Ablation of Atrial Fibrillation.
This article provides an overview of current surgical strategies for patients with atrial fibrillation and addresses the two main goals in its management. PMID: 26306128 [PubMed - in process]
Source: Methodist DeBakey Cardiovascular Journal - April 1, 2015 Category: Cardiology Authors: Ramlawi B, Abu Saleh WK Tags: Methodist Debakey Cardiovasc J Source Type: research

The health status of adults on the autism spectrum
The objective of this study was to describe the frequency of psychiatric and medical conditions among a large, diverse, insured population of adults with autism in the United States. Participants were adult members of Kaiser Permanente Northern California enrolled from 2008 to 2012. Autism spectrum disorder cases (N = 1507) were adults with autism spectrum disorder diagnoses (International Classification of Diseases-9-Clinical Modification codes 299.0, 299.8, 299.9) recorded in medical records on at least two separate occasions. Controls (N = 15,070) were adults without any autism spectrum disorder diagnoses sampled at a 1...
Source: Autism - September 22, 2015 Category: Neurology Authors: Croen, L. A., Zerbo, O., Qian, Y., Massolo, M. L., Rich, S., Sidney, S., Kripke, C. Tags: Special Issue Articles Source Type: research

Internal carotid artery injury in endoscopic endonasal surgery: A systematic review
ConclusionsThe incidence of reported cases of ICA injury during EES remains low. Left‐sided injuries to the cavernous segment of the ICA occurred more frequently than injuries on the right. Level of EvidenceNA Laryngoscope, 2015
Source: The Laryngoscope - November 3, 2015 Category: ENT & OMF Authors: Oliver Y. Chin, Ritam Ghosh, Christina H. Fang, Soly Baredes, James K. Liu, Jean Anderson Eloy Tags: Cranial Base Source Type: research

Non-invasive hemodynamic analysis in cardiac resynchronization therapy patients wearing quadripolar left ventricular leads: the importance of pacing electrode selection.
CONCLUSION: Our study demonstrates that different bipolar pacing configurations, even if arising from a single CS branch, substantially modify the hemodynamic effect of LV pacing in CRT patients. Moreover, the non-invasive hemodynamic analysis suggests the better pacing configuration should be established individually and could represent an important issue in optimizing CRT during follow-up. PMID: 25275712 [PubMed - indexed for MEDLINE]
Source: Minerva Cardioangiologica - November 18, 2015 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Comparison of hemodynamic changes between old and very old patients undergoing cemented bipolar hemiarthroplasty under spinal anesthesia.
CONCLUSIONS: Bone cement implantation during bipolar hemiarthroplasty may cause more prominent hemodynamic changes in very elderly patients. Careful hemodynamic monitoring and management are warranted in very elderly patients undergoing cemented bipolar hemiarthroplasty. PMID: 25664154 [PubMed]
Source: Korean Journal of Anesthesiology - November 18, 2015 Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research

Dissociative disorders and affective disorders.
We describe here two cases who were initially misdiagnosed. The first case concerned a 61 year-old woman, who was initially diagnosed as an isolated dissociative fugue and was actually suffering from severe major depressive episode. The second case concerned a 55 year-old man, who was suffering from type I bipolar disorder and polyvascular disease, and was initially diagnosed as dissociative fugue in a mooddestabilization context, while it was finally a stroke. Yet dissociative disorders as affective disorder comorbidity are relatively unknown. We made a review on this topic. Dissociative disorders are often studied throug...
Source: L Encephale - November 20, 2015 Category: Psychiatry Tags: Encephale Source Type: research

Human trials suggest 'rescued' drug could be safer treatment for bipolar disorder
(University of Oxford) Ebselen, abandoned as a stroke treatment, has a successful first human trial as Oxford scientists aim to repurpose it as a treatment for bipolar disorder.
Source: EurekAlert! - Medicine and Health - December 8, 2015 Category: Global & Universal Source Type: news