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Total 381 results found since Jan 2013.

025 * ablative maze surgery normalizes left ventricular function in patients with lone atrial fibrillation
Conclusions: Within a dedicated AF centre, ablative maze surgery grants excellent outcomes, with symptom relief and negligible risk. It provides a complete reversal of AF-related myocardial dysfunction and is therefore a convenient alternative to His bundle ablation and lifelong pacemaker dependency in symptomatic refractory patients.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Pozzoli, A., Taramasso, M., Coppola, G., Kamami, M., La Canna, G., Della Bella, P., Alfieri, O., Benussi, S. Tags: Arrhythmia I Source Type: research

The development of delusion revisited: A transdiagnostic framework
This study proposes a transdiagnostic framework for delusion development, analysing psychiatric (schizophrenia, bipolar disorder, major depressive disorder) and neurological disorders (stroke, and neurodegenerative diseases) in which delusions are predominant. Our aim is to identify a transdiagnostic core of neural and cognitive alterations associated with delusions across distinct clinical disorders. Reviewed empirical evidence suggests delusions are associated: on the neural level with changes in the ventromedial prefrontal cortex (vmPFC) networks, and on the neuropsychological level with dysfunction in the processes (ge...
Source: Psychiatry Research - August 26, 2013 Category: Psychiatry Authors: Michele Poletti, Fabio Sambataro Tags: Reviews Source Type: research

Cost-effectiveness of asenapine in the treatment of bipolar disorder in Canada
Conclusion: This economic evaluation demonstrates that asenapine is a cost-effective strategy compared to olanzapine in the treatment of BPD in Canada.
Source: BMC Psychiatry - Latest articles - January 22, 2014 Category: Psychiatry Authors: Jean LachaineCatherine BeaucheminKarine MathurinDominique GilbertMaud Beillat Source Type: research

Got Bipolar? You're at Risk for Metabolic Syndrome, Too
A study found that people with bipolar disorder are up to twice as likely as the general population to have metabolic syndrome, a cluster of symptoms that increase your risk of heart problems, stroke and diabetes. The study, published in the Journal of Affective Disorders, also found that "co-occurrence of metabolic syndrome in the bipolar population is associated with a more complex illness presentation, less favorable response to treatment, and adverse course and outcome." In other words, for people with bipolar disorder, both the bipolar and the metabolic syndrome are likely to be more serious and harder to treat. Why ...
Source: About.com Bipolar Disorder - February 18, 2014 Category: Psychiatry Source Type: news

The Role of Toll-Like Receptor 3 in Epileptogenesis (I1-2.001)
Conclusion:These preliminary results -in a still ongoing study- indicate a central involvement of seizure induction (epileptogenesis) by TLR3 and provide evidence for future research and possibly drug development to finally change the treatment paradigm of epilepsy from symptomatic seizure control to curable prevention of seizure development.Disclosure: Dr. Benninger has nothing to disclose. Dr. Gross has nothing to disclose. Dr. Steiner has received personal compensation for activities with Actelion and Hoffman La Roche. Dr. Offen has nothing to disclose. Dr. Okun has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Benninger, F., Gross, A., Steiner, I., Offen, D., Okun, E. Tags: Temporal Lobe Epilepsy and Febrile Seizures Data Blitz Presentations Source Type: research

The Role of Toll-Like Receptor 3 in Epileptogenesis (S29.002)
Conclusion:These preliminary results -in a still ongoing study- indicate a central involvement of seizure induction (epileptogenesis) by TLR3 and provide evidence for future research and possibly drug development to finally change the treatment paradigm of epilepsy from symptomatic seizure control to curable prevention of seizure development.Disclosure: Dr. Benninger has nothing to disclose. Dr. Gross has nothing to disclose. Dr. Steiner has received personal compensation for activities with Actelion and Hoffman La Roche. Dr. Offen has nothing to disclose. Dr. Okun has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Benninger, F., Gross, A., Steiner, I., Offen, D., Okun, E. Tags: Epilepsy and Clinical Neurophysiology: Inflammation, Status Epilepticus, and Genetics Source Type: research

Clinical Reasoning: Acute-onset homonymous hemianopia with hyperglycemia: Seeing is believing
A 32-year-old woman with a history of bipolar disorder, polycystic ovarian syndrome, and hypertension and a 4-year history of uncontrolled type 2 diabetes mellitus (DM) presented with bifrontal headache, elevated blood sugars (>500 mg/dL), and abrupt-onset left homonymous hemianopia upon awakening. Vital signs included temperature 98.0°F, blood pressure 160/89 mm Hg, and heart rate 67 bpm. Neurologic examination showed dense left homonymous hemianopia with macular sparing and without other focal findings.
Source: Neurology - April 14, 2014 Category: Neurology Authors: Strowd, R. E., Wabnitz, A., Balakrishnan, N., Craig, J., Tegeler, C. H. Tags: Endocrine, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Psychiatric and neurologic risk factors for incident cases of new‐onset epilepsy in older adults: Data from U.S. Medicare beneficiaries
Summary ObjectiveNeurologic diseases such as stroke are risk factors for new‐onset epilepsy in older adults. Recent evidence suggests that psychiatric disorders independently predict epilepsy in older male veterans. Our aim was to examine the relationship between these disorders in a population‐based study of older adults that also included women and minorities. MethodsWe used a national 5% random sample of 2005 Medicare beneficiaries including all 50 US states and Washington, DC. Beneficiaries were 65 years of age or older, with continuous Medicare Part A and Part B coverage and not in managed care plans. Epilepsy ca...
Source: Epilepsia - June 5, 2014 Category: Neurology Authors: Roy C. Martin, Edward Faught, Joshua Richman, Ellen Funkhouser, Yongin Kim, Kay Clements, Maria Pisu Tags: Full‐Length Original Research Source Type: research

Citicoline in addictive disorders: a review of the literature.
Conclusions: Currently, there is limited research on the efficacy of citicoline for addictive disorders, but the available literature suggests promising results. Future research should employ larger sample sizes, increased dosing, and more complex study designs. PMID: 24950234 [PubMed - as supplied by publisher]
Source: The American Journal of Drug and Alcohol Abuse - June 20, 2014 Category: Addiction Authors: Wignall ND, Brown ES Tags: Am J Drug Alcohol Abuse Source Type: research

Thoracoscopic Radiofrequency Ablation for Lone Atrial Fibrillation: Box‐Lesion Technique
ConclusionThe thoracoscopic box‐lesion ablation procedure is a safe, effective, and minimally invasive method for the treatment of isolated (lone) AF. This procedure provided excellent short‐term freedom from AF.
Source: Journal of Cardiac Surgery - July 1, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Marek Pojar, Jan Vojacek, Ludek Haman, Petr Parizek, Nedal Omran, Martin Vobornik, Jan Harrer Tags: Original Article Source Type: research

Long-Term Follow-Up Shows Excellent Transmural Atrial Lead Performance in Patients With Complex Congenital Heart Disease Original Articles
Conclusions— TMA pacing leads had excellent longevity, initial, and chronic functional properties and provide an alternative to epicardial leads in patients with congenital heart disease. Patients who cannot receive transvenous leads, have epicardial scarring or have intra-atrial re-entrant tachycardia could benefit most from routine use of this technique.
Source: Circulation: Arrhythmia and Electrophysiology - August 19, 2014 Category: Cardiology Authors: Williams, M. R., Shepard, S. M., Boramanand, N. K., Lamberti, J. J., Perry, J. C. Tags: Electrophysiology, Pacemaker, Pediatric and congenital heart disease, including cardiovascular surgery, Arrhythmias, clinical electrophysiology, drugs Original Articles Source Type: research

Subliminal galvanic-vestibular stimulation influences ego- and object-centred components of visual neglect
In conclusion, subliminal GVS modulates ego- and object-centred components of visual neglect rapidly. Implications for neurorehabilitation are discussed.
Source: Neuropsychologia - November 12, 2014 Category: Neurology Source Type: research

Maze surgery normalizes left ventricular function in patients with persistent lone atrial fibrillation ADULT CARDIAC
CONCLUSIONS Within a dedicated AF centre, maze surgery grants excellent outcomes, with symptoms relief and negligible risk. It provides a complete reversal of arrhythmia-related myocardial dysfunction and is therefore a convenient alternative to His bundle ablation and lifelong pacemaker dependency in symptomatic refractory patients.
Source: European Journal of Cardio-Thoracic Surgery - October 10, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Pozzoli, A., Taramasso, M., Coppola, G., Kamami, M., La Canna, G., Bella, P. D., Alfieri, O., Benussi, S. Tags: Minimally invasive surgery, Myocardial infarction, Myocardial protection, Transplantation - heart ADULT CARDIAC Source Type: research

Effectiveness of horticultural therapy: A systematic review of randomized controlled trials.
CONCLUSION: Although there was insufficient evidence in the studies of HT due to poor methodological and reporting quality and heterogeneity, HT may be an effective treatment for mental and behavioral disorders such as dementia, schizophrenia, depression, and terminal-care for cancer. PMID: 25440385 [PubMed - in process]
Source: Complementary Therapies in Medicine - October 1, 2014 Category: Complementary Medicine Authors: Kamioka H, Tsutani K, Yamada M, Park H, Okuizumi H, Honda T, Okada S, Park SJ, Kitayuguchi J, Abe T, Handa S, Mutoh Y Tags: Complement Ther Med Source Type: research

The Use of Quadripolar Left Ventricular Leads Improves the Hemodynamic Response to Cardiac Resynchronization Therapy
ConclusionsThe quadripolar LV lead was associated with a better hemodynamic response and higher CRT responder rates when compared with unipolar‐simulated and bipolar LV leads.
Source: Pacing and Clinical Electrophysiology : PACE - December 1, 2014 Category: Cardiology Authors: JOAQUÍN OSCA, PAU ALONSO, ÓSCAR CANO, JUAN MIGUEL SÁNCHEZ, DAVID TEJADA, ANA ANDRÉS, MARÍA JOSÉ SANCHO TELLO, JOSÉ OLAGÜE Tags: ORIGINAL ARTICLE Source Type: research