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Condition: Eczema
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Total 2491 results found since Jan 2013.
Skin Barrier Dysfunction In Patients With Peanut Allergy Without Eczema
Atopic dermatitis (AD+) with peanut allergy (PA+) is associated with increased transepidermal water loss (TEWL), low urocanic acid (UCA, a filaggrin breakdown product), and reduced ratio of EOS-ceramides to NS-ceramides. Here we explored whether PA without AD (AD-PA+) also had skin barrier abnormalities.
Source: Journal of Allergy and Clinical Immunology - January 31, 2020 Category: Allergy & Immunology Authors: Donald Leung, Elena Goleva, Bryce Hoffman, Anna Sofia Bronoff, John Jung, Shannon Garcia, Marco Ramirez-Gama, Shifaa Alkotob, Kari Nadeau, Christine Cho, Irina Bronova, Evgeny Berdyshev Source Type: research
POEM correlates with EASI and other measures better than PO-SCORAD: A validation study.
CONCLUSION: PO-SCORAD and POEM showed good construct and cross-cultural validity, reliability, and responsiveness in adults with AD, and were feasible for use in clinical trials and practice. However, POEM showed better measurement properties than PO-SCORAD.
PMID: 32199977 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 17, 2020 Category: Allergy & Immunology Authors: Silverberg JI, Lei D, Yousaf M, Janmohamed SR, Vakharia PP, Chopra R, Chavda R, Gabriel S, Patel KR, Singam V, Kantor R, Hsu DY Tags: Ann Allergy Asthma Immunol Source Type: research
A real-world study of the longitudinal course of adult atopic dermatitis severity in clinical practice.
CONCLUSION: AD lesional severity has a heterogeneous longitudinal course. Many patients had fluctuating lesional severity scores over time. A minority of patients had persistently moderate or severe lesions over time. Most patients with moderate-severe disease at baseline were unable to achieve persistent lesional clearance.
PMID: 32682980 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 15, 2020 Category: Allergy & Immunology Authors: Hong MR, Lei D, Yousaf M, Chavda R, Gabriel S, Janmohamed SR, Silverberg JI Tags: Ann Allergy Asthma Immunol Source Type: research
The Infectious Complications of Atopic Dermatitis.
CONCLUSION: Infectious complications are a co-morbidity of AD. Although not common, systemic bacterial infections and eczema herpeticum can be life-threatening. Preventive therapy of infections in AD emphasizes skin barrier improvement and anti- inflammatory therapy. The use of antibiotics in AD exacerbation requires further studies.
PMID: 32771354 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - August 5, 2020 Category: Allergy & Immunology Authors: Wang V, Boguniewicz J, Boguniewicz M, Ong PY Tags: Ann Allergy Asthma Immunol Source Type: research
Efficacy, Safety, and Immunomodulatory Effect of the Intramuscular Administration of Autologous Total Immunoglobulin G for Atopic Dermatitis: A Randomized Clinical Trial.
CONCLUSIONS: The intramuscular administration of autologous total IgG provided clinical improvements and a systemic immunomodulatory effect in adolescent and adult patients with moderate-to-severe AD without significant side effects.
TRIAL REGISTRATION: Clinical Research Information Service Identifier: KCT0001597.
PMID: 32935488 [PubMed]
Source: Allergy, Asthma and Immunology Research - September 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Evaluation of Olfactory Function in Children With Vernal Keratoconjunctivitis.
CONCLUSION: Olfactory function was found to be mildly impaired in children with VKC, especially when co-associated with AR. Therefore, loss of smell should be asked as an extraocular symptom.
PMID: 33225727 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - November 22, 2020 Category: ENT & OMF Authors: Elsürer Ç, Bozkurt B, Aksoy Md C, Bozkurt MK Tags: Am J Rhinol Allergy Source Type: research
Traditional Chinese Medicine for Food Allergy and Eczema
To summarize the recent evidence of traditional Chinese medicine (TCM) for food allergy and eczema.
Source: Annals of Allergy, Asthma and Immunology - December 10, 2020 Category: Allergy & Immunology Authors: Zixi Wang, Zhen-Zhen Wang, Jan Geliebter, Raj Tiwari, Xiu-Min Li Tags: Review Source Type: research
Atopic Dermatitis in the Pediatric Population: A Cross-sectional, International, Epidemiologic Study.
CONCLUSION: This global survey in 18 countries showed that AD affects a substantial proportion of the pediatric population. Although prevalence and severity varied across age groups and countries, <15% had severe AD.
PMID: 33421555 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 6, 2021 Category: Allergy & Immunology Authors: Silverberg JI, Barbarot S, Gadkari A, Simpson EL, Weidinger S, Mina-Osorio P, Rossi AB, Brignoli L, Saba G, Guillemin I, Fenton MC, Auziere S, Eckert L Tags: Ann Allergy Asthma Immunol Source Type: research
An Unexpected Infection in Loss-of-Function Mutations in STAT3: Malignant Alveolar Echinococcosis in Liver.
Abstract
Loss-of-function (LOF) mutations in signal transducer and activator of transcription 3 (STAT3) gene causes autosomal dominant hyper immunoglobulin E syndrome (AD-HIES or Job's Syndrome), a rare and complex primary immunodeficiency (PID) syndrome characterized by increased levels of IgE (>2000 IU/mL), eosinophilia, recurrent staphylococcal skin abscesses, eczema, recurrent pneumonia, skeletal and connective tissue abnormalities. Although bacterial and fungal infections are common in AD-HIES, susceptibility to parasitic infections has not been reported. Alveolar echinococcosis (AE), a zoonosis caused by ...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 19, 2020 Category: Allergy & Immunology Authors: Haskologlu S, Dogu F, Gollu Bahadır G, Akyuzluer S, Ciftci E, Altun D, Keles S, Kologlu M, Ikinciogullari A Tags: Iran J Allergy Asthma Immunol Source Type: research
Disparities of GERD treatment and Gastroenterology Care in Black Children with Food Allergy in FORWARD Cohort
This study assesses the relationship between race, GERD, FA type, asthma, eczema, and gastroenterology consultation.
Source: Journal of Allergy and Clinical Immunology - February 1, 2021 Category: Allergy & Immunology Authors: Mary Tobin, Jamie Fierstein, Jialing Jiang, Aame Andy-Nweye, Susan Fox, Mahboobeh Mahdavinia, Andrea Pappalardo, Annika Chura, Amal Assa'ad, Adam Robinson, Hemant Sharma, Amaziah Coleman, Lucy Bilaver, Christopher Warren, Pamela Newmark, Alexandria Bozen, Source Type: research
Heterogeneous associations of polyomaviruses and herpesviruses with allergy-related phenotypes in childhood
CONCLUSION: A heterogeneous pattern of infections and allergic diseases was observed with common infections associated to a decreased eczema risk and an increased asthma risk in children.PMID:33895421 | DOI:10.1016/j.anai.2021.04.019
Source: Annals of Allergy, Asthma and Immunology - April 25, 2021 Category: Allergy & Immunology Authors: Marianna Karachaliou Silvia de Sanjose Theano Roumeliotaki Katerina Margetaki Marina Vafeiadi Tim Waterboer Leda Chatzi Manolis Kogevinas Source Type: research
Leveraging shared decision making to discuss nonessential medical testing and prevent peanut allergy overdiagnosis during infancy
We read with interest the recent report by Keet et al1 describing the use of Ara h 2–specific IgE (sIgE) as a peanut allergy screening tool in infants with moderate to severe eczema, compared with peanut skin prick test and whole peanut sIgE.1 The authors report a sensitivity of 94% and near-perfect specificity of 98% at an “optimal” 0.1 kU/ L cutoff value for Ara h 2-sIgE in this sample. At 0.35 kU/L, these values were 89% (sensitivity) and 99% (specificity).1 The trial was conducted primarily at 1 center and enriched for infants with moderate to severe eczema.
Source: Journal of Allergy and Clinical Immunology - April 26, 2021 Category: Allergy & Immunology Authors: Matthew Greenhawt, John Oppenheimer, Elissa M. Abrams, Rachel L. Peters, Marcus Shaker Tags: Correspondence Source Type: research
Heterogeneous associations of polyomaviruses and herpesviruses with allergy-related phenotypes in childhood
CONCLUSION: A heterogeneous pattern of infections and allergic diseases was observed with common infections associated to a decreased eczema risk and an increased asthma risk in children.PMID:33895421 | DOI:10.1016/j.anai.2021.04.019
Source: Annals of Allergy, Asthma and Immunology - April 25, 2021 Category: Allergy & Immunology Authors: Marianna Karachaliou Silvia de Sanjose Theano Roumeliotaki Katerina Margetaki Marina Vafeiadi Tim Waterboer Leda Chatzi Manolis Kogevinas Source Type: research
Shorter “time to peanut introduction” can prevent peanut allergy and avert false Ara h 2 screening results in infants
We echo the importance of estimating precise pretest probabilities based on the degree of appropriate risk factors —a task potentially enabled by data presented by Keet et al1,2—to fully evaluate the utility of screening tests for the purposes of infant peanut introduction. Diagnostic test operating characteristics are central to the screening controversy in peanut allergy prevention.3 Assuming the authors’ data are generalizable to the US population of infants with moderate to severe eczema, Ara h 2 component IgE appears to be superior to skin prick testing and to peanut-specific IgE testing, with Ara h 2 having th...
Source: Journal of Allergy and Clinical Immunology - May 6, 2021 Category: Allergy & Immunology Authors: Edward G.A. Iglesia, Edwin H. Kim Tags: Correspondence Source Type: research
Association between Household Income and Allergy Development in Children: The Japan Environment and Children ’s Study
Conclusion: Low household income was a risk for doctor-diagnosed asthma and eczema, suggesting that public health professionals should recognize low-income groups as vulnerable populations for these conditions.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - October 1, 2021 Category: Allergy & Immunology Source Type: research
