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Specialty: Neuroscience
Condition: Aphasia

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Total 183 results found since Jan 2013.

Mapping the intersection of language and reading: the neural bases of the primary systems hypothesis.
This study provided the first quantitative investigation of this account at both behavioural and neural levels in a group of patients with chronic post-stroke aphasia. Principal components analysis was used to distil orthogonal measures of phonological and semantic processing, which were then related to reading performance and the underlying lesion distributions using voxel-based correlational methodology. Concrete word reading involved both a ventral semantic pathway, and inferior and anterior aspects of the dorsal phonological pathway. Abstract word reading overlapped with the ventral semantic pathway but also drew more ...
Source: Brain Structure and Function - August 2, 2018 Category: Neuroscience Authors: Woollams AM, Halai A, Lambon Ralph MA Tags: Brain Struct Funct Source Type: research

The potential effects of transcranial direct current stimulation (tDCS) on language functioning: Combining neuromodulation and behavioral intervention in aphasia
Publication date: Available online 28 December 2017Source: Neuroscience LettersAuthor(s): Paola MarangoloAbstractAphasia is a highly disabling language disorder usually caused by a left stroke brain damage. Even if traditional language therapies have been proved to induce an adequate clinical recovery, a large percentage of patients are left with chronic deficits at 6 months post-stroke. Therefore, new strategies to common speech therapies are urgently needed in order to maximize the recovery from aphasia. The recent application of transcranial direct current stimulation (tDCS) to language rehabilitation has already provid...
Source: Neuroscience Letters - July 18, 2018 Category: Neuroscience Source Type: research

Transcranial direct current stimulation (tDCS) facilitates verb learning by altering effective connectivity in the healthy brain
Publication date: Available online 17 July 2018Source: NeuroImageAuthor(s): Valentina Fiori, Lisa Kunz, Philipp Kuhnke, Paola Marangolo, Gesa HartwigsenAbstractRecent studies have shown that the left inferior frontal gyrus (IFG) plays a key role in language learning. Facilitatory stimulation over this region by means of anodal transcranial direct current stimulation (tDCS) can modulate linguistic abilities in healthy individuals and improve language performance in patients with post-stroke aphasia. Neuroimaging studies in healthy participants have suggested that anodal tDCS decreases task-related activity at the stimulated...
Source: NeuroImage - July 18, 2018 Category: Neuroscience Source Type: research

The potential effects of transcranial direct current stimulation (tDCS) on language functioning: Combining neuromodulation and behavioral intervention in aphasia
Publication date: Available online 28 December 2017Source: Neuroscience LettersAuthor(s): Paola MarangoloAbstractAphasia is a highly disabling language disorder usually caused by a left stroke brain damage. Even if traditional language therapies have been proved to induce an adequate clinical recovery, a large percentage of patients are left with chronic deficits at 6 months post-stroke. Therefore, new strategies to common speech therapies are urgently needed in order to maximize the recovery from aphasia. The recent application of transcranial direct current stimulation (tDCS) to language rehabilitation has already provid...
Source: Neuroscience Letters - July 5, 2018 Category: Neuroscience Source Type: research

An Emergent Large Vessel Occlusion Screening Protocol for Acute Stroke: A Quality Improvement Initiative
Background: Nurses play an integral role in triaging stroke patients. The purpose of this quality improvement initiative was to determine the efficacy of using an emergent large vessel occlusion (ELVO) screening protocol in the emergency department by nursing staff to improve identification of eligible patients as compared with current practice, improving time to endovascular treatment. Methods: Retrospective chart review was used to identify 76 patients admitted to a large urban stroke center. Of these, 36 presented during a 4-month period before the implementation of the Stroke Vision, Aphasia, Neglect (Stroke VAN) tool ...
Source: Journal of Neuroscience Nursing - March 13, 2018 Category: Neuroscience Tags: Article Source Type: research

Wants Talk Psychotherapy but Cannot Talk: EMDR for Post-stroke Depression with Expressive Aphasia
CONCLUSION This is the first reported case demonstrating that EMDR can be effective for depression, even in those with severe expressive aphasia. In our case, there was no reluctance to disclose information, simply a neurological inability to do so. Through preparation, patience, perseverance, and plasticity (clinician flexibility, though perhaps also neuroplasticity), the patient’s PSD gradually improved, and she was able to reinvent her life within her limitations. ACKNOWLEDGMENTS The authors gratefully acknowledge Eugene Schwartz, E.C. Hurley, and Mark Hubner for providing consultation during patient care. REFERENCES ...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Neurologic Systems and Symptoms Neurology Psychotherapy Stroke aphasia depression EMDR Source Type: research

Editorial Message and Issue Highlights – Vol. 15, No. 1 –2, January-February 2018
Dear Colleagues: Welcome to the January-February 2018 issue of Innovations in Clinical Neuroscience (ICNS). This is a milestone year for us as it marks the beginning of our 15th year of publication! We are pleased to continue serving you, our valued readers and colleagues, by providing peer-reviewed, evidence-based information on the latest innovations in both research and clinical practice in the field of neuroscience. We’d like to thank those dedicated readers who have been with us since 2004, the year we launched the journal, and to welcome new readers who are just discovering ICNS and what it has to offer. We’d als...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Current Issue Editor's Message: Issue Highlights Source Type: research

Letter to the Editor: Pneumocephalus: Is the needle size significant?
Discussion. Pneumocephalus is defined by two mechanisms: a ball-valve and an inverted bottle concept.1 The ball-valve type implies positive pressure events, such as coughing or valsalva maneuvers, that prevent air escape. Tension pneumocephalus is included in this mechanism, causing a parenchymal mass effect. The inverted bottle theory includes a negative intracranial pressure gradient following cerebrospinal fluid drainage, relieved by air influx. A small pneumocephalus is usually sealed by blood clots or granulation, allowing spontaneous reabsorption and resolution.[1] Otherwise, the lateral positioning of a patient duri...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools CNS Infections Current Issue Letters to the Editor Neurologic Systems and Symptoms Neurology Stroke Traumatic Brain Injury epidural needle size Pneumocephalus spinal tap Source Type: research

Sensorimotor impairment of speech auditory feedback processing in aphasia
Publication date: 15 January 2018 Source:NeuroImage, Volume 165 Author(s): Roozbeh Behroozmand, Lorelei Phillip, Karim Johari, Leonardo Bonilha, Chris Rorden, Gregory Hickok, Julius Fridriksson We investigated the brain network involved in speech sensorimotor processing by studying patients with post-stroke aphasia using an altered auditory feedback (AAF) paradigm. We combined lesion-symptom-mapping analysis and behavioral testing to examine the pervasiveness of speech sensorimotor deficits and their relationship with cortical damage. Sixteen participants with aphasia and sixteen neurologically intact individuals complete...
Source: NeuroImage - October 16, 2017 Category: Neuroscience Source Type: research

Aphasia As a Predictor of Stroke Outcome
AbstractPurpose of ReviewAphasia is a common feature of stroke, affecting 21 –38% of acute stroke patients and an estimated 1 million stroke survivors. Although stroke, as a syndrome, is the leading cause of disability in the USA, less is known about the independent impact of aphasia on stroke outcomes.Recent FindingsDuring the acute stroke period, aphasia has been found to increase length of stay, inpatient complications, overall neurological disability, mortality, and to alter discharge disposition. Outcomes during the sub-acute and chronic stroke periods show that aphasia is associated with lower Functional Independen...
Source: Current Neurology and Neuroscience Reports - September 19, 2017 Category: Neuroscience Source Type: research

Altered Structure and Intrinsic Functional Connectivity in Post-stroke Aphasia.
Abstract Previous studies have demonstrated that alterations of gray matter exist in post-stroke aphasia (PSA) patients. However, so far, few studies combined structural alterations of gray matter volume (GMV) and intrinsic functional connectivity (iFC) imbalances of resting-state functional MRI to investigate the mechanism underlying PSA. The present study investigated specific regions with GMV abnormality in patients with PSA (n = 17) and age- and sex- matched healthy controls (HCs, n = 20) using voxel-based morphometry. In addition, we examined whether there is a link between abnormal gray matter and al...
Source: Brain Topography - September 18, 2017 Category: Neuroscience Authors: Yang M, Yang P, Fan YS, Li J, Yao D, Liao W, Chen H Tags: Brain Topogr Source Type: research

Whole-brain functional connectome-based multivariate classification of post-stroke aphasia
Publication date: 20 December 2017 Source:Neurocomputing, Volume 269 Author(s): Mi Yang, Jiao Li, Zhiqiang Li, Dezhong Yao, Wei Liao, Huafu Chen Patients with post-stroke aphasia (PSA) show abnormalities of intrinsic functional connectivity. However, whether the whole-brain functional connectome can be used as a feature to distinguish patients with PSA from healthy controls is poorly understood. We aim to distinguish PSA patients from controls using whole-brain functional connectivity-based multivariate pattern analysis. These features would be helpful in the understanding of the pathophysiology of PSA. In the present stu...
Source: Neurocomputing - September 10, 2017 Category: Neuroscience Source Type: research

P 67 Electrophysiological correlates of language improvements after intensive language therapy in patients with chronic post-stroke aphasia
Aphasia affects approximately one third of all stroke patients and may lead to chronic disability. Effective neurorehabilitation programs focusing on improving speech and language in patients with post-stroke aphasia are essential. A better understanding of the neurobiological processes accompanying language deficits and rehabilitation may bear fruit in the advancement of neurorehabilitation programs.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: G. Lucchese, F. Pulverm üller, B. Stahl, F. Dreyer, B. Mohr Tags: Poster Source Type: research

FV 13 Electrophysiological correlates of language recovery – an MEG study of neuroplasticity in chronic post stroke aphasia
Previous studies have demonstrated that efficient language and communication therapy in chronic post stroke aphasia leads to significant clinical language improvements (Pulverm üller et al., 2001) and promotes neuroplasticity. Brain areas frequently associated with functional restitution of language comprise perilesional sites in the left hemisphere (MacGregor et al., 2015) as well as right-hemispheric regions, homotopic to those lesioned in the left (Mohr et al., 2014). To date, however, the neuronal mechanisms underlying therapy-induced language changes and functional restitution are still largely unclear.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: B. Mohr, S. Difrancesco, L. MacGregor, Y. Shtyrov Tags: Free Lecture Source Type: research

P 165 Incidence, clinical characteristics and longterm course of headache in patients with stroke (DMKG multicenter study)
Post stroke headache is a symptom which is generally not further differentiated. According to previous European and American studies, it is a common phenomenon. Nevertheless, other symptoms of stroke, such as palsy or aphasia, are dominating clinical assessments. However, the symptom “headache” can be an essential part of the clinical picture as in subarachnoid bleeding or cerebral venous thrombosis and it is unclear which risk factors modulate the symptoms and the occurrence of headache in stroke.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: S. Dietrich, A. D üring, D. Rothkirch, F. Filippopulos, O. Eren, T. Dresler, T. Buchwald, A. Straube, S. Zierz, G. Goßrau, T. Kraya Tags: Poster Source Type: research