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Age Threshold for Increased Stroke Risk Among Patients With Atrial Fibrillation A Nationwide Cohort Study From Taiwan
This study hypothesized that the age threshold (65 years) used in the CHA2DS2-VASc system for initiating oral anticoagulants (OACs) might be lower in Taiwanese AF patients than in non-Asians.MethodsWe used the National Health Insurance Research Database in Taiwan to study 186,570 nonanticoagulated AF patients. There were 9,416 males with a CHA2DS2-VASc score of 0 and 6,390 females with a CHA2DS2-VASc score of 1. Their risk of ischemic stroke was analyzed with stratification on the basis of age.ResultsThe annual risks of ischemic stroke for males (score 0) and females (score 1) were 1.15% and 1.12%, respectively, and contin...
Source: Journal of the American College of Cardiology - September 14, 2015 Category: Cardiology Source Type: research

Neck dissection and stroke in patients with oral cavity cancer: A population‐based cohort study
ConclusionOur data demonstrate that neck dissection does not increase the risk of stroke in patients with oral cavity cancer. Patients have higher risk of stroke after cancer treatment because of their older age, specific comorbidities, and/or type of postoperative treatment. © 2016 Wiley Periodicals, Inc. Head Neck, 2016
Source: Head and Neck - July 19, 2016 Category: ENT & OMF Authors: Chia‐Fan Chang, Yen‐Ling Kuo, Christy Pu, Yiing‐Jenq Chou Tags: Original Article Source Type: research

Neck dissection and stroke in patients with oral cavity cancer: A population ‐based cohort study
ConclusionOur data demonstrate that neck dissection does not increase the risk of stroke in patients with oral cavity cancer. Patients have higher risk of stroke after cancer treatment because of their older age, specific comorbidities, and/or type of postoperative treatment. © 2016 Wiley Periodicals, Inc. Head Neck, 2016
Source: Head and Neck - July 19, 2016 Category: ENT & OMF Authors: Chia ‐Fan Chang, Yen‐Ling Kuo, Christy Pu, Yiing‐Jenq Chou Tags: Original Article Source Type: research

Elucidating the Association Between Depressive Symptoms, Coronary Heart Disease, and Stroke in Black and White Adults: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study Epidemiology
Conclusions Proximal depressive symptoms were associated with incident fatal and nonfatal stroke and CVD death even after controlling for multiple explanatory factors, further supporting the urgent need for timely management of depressive symptoms.
Source: JAHA:Journal of the American Heart Association - August 11, 2016 Category: Cardiology Authors: Moise, N., Khodneva, Y., Richman, J., Shimbo, D., Kronish, I., Safford, M. M. Tags: Quality and Outcomes Epidemiology Source Type: research

Specificities of Ischemic Stroke Risk Factors in Arab-Speaking Countries
Background: Stroke is largely preventable, and therefore, a better understanding of risk factors is an essential step in reducing the population stroke rate and resulting disease burden in Arab countries.Summary: We performed 2 separate analyses in 2 similar populations of patients with noncardioembolic ischemic stroke. This first involved 3,635 patients in the Outcomes in Patients with TIA and Cerebrovascular disease (OPTIC) registry (followed for 2 years), with baseline collection of the usual risk factors and 5 socioeconomic variables (unemployment status, residence in rural area, living in fully serviced accommodation,...
Source: Cerebrovascular Diseases - February 15, 2017 Category: Neurology Source Type: research

Association between Preexisting Sarcopenia and Stroke in Patients with Type 2 Diabetes Mellitus
ConclusionPreexisting sarcopenia increased the risk of stroke in patients with type 2 diabetes mellitus.
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

The impact of comorbidity on survival after hemorrhagic stroke among dialysis patients: a nationwide population-based study
Conclusions: Dialysis patients who have history of prior stroke, diabetes and malignancy have worse survival than patients without these comorbidities. Attention must focus on providing optimal medical care after hemorrhagic stroke for these target groups to reduce mortality.
Source: BMC Nephrology - November 27, 2014 Category: Urology & Nephrology Authors: Chun-Yu LinChih-Chiang ChienHung-An ChenFu-Mei SuJhi-Joung WangChe-Chuan WangChin-Chen ChuYeong-Jang Lin Source Type: research

Baseline characteristics in stroke patients with atrial fibrillation: clinical trials versus clinical practice
Conclusions: The majority of stroke patients with AF in the clinical setting are considerably older than those included in clinical trials. While the distribution of vascular risk factors in clinical trials corresponds to proportions observed in clinical practice, an overrepresentation of the male sex in clinical trials is evident.
Source: BMC Research Notes - June 25, 2015 Category: Research Authors: Christian TanislavSonja MildeSabine SchwartzkopffBjörn MisselwitzNicole SiewekeManfred Kaps Source Type: research

Does early onset cataract increase the risk of ischemic stroke? A nationwide retrospective cohort study
This study was attempted to address the association between early onset cataract (EOC) and ischemic stroke. Using the Longitudinal Health Insurance Database 2000, we established an EOC cohort and a comparison cohort by using 4-fold propensity score matching according to age, gender and comorbidities to detect the incidence of ischemic stroke. A Cox model was used to express the risk of ischemic stroke for the EOC patients compared with the comparison cohort. After adjusting for age, gender and comorbidities of hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, asthma, chronic obstructive pulmonary...
Source: Internal and Emergency Medicine - December 21, 2016 Category: Emergency Medicine Source Type: research

Derivation and Validation of a Proposed Long Length of Stay (>= 7 days) Score in Patients Hospitalized for Acute Ischemic Stroke (P1.067)
Conclusions:Many factors play a role in determining the length of stay for AIS patients. Our study provides a scoring system that may help physicians predict which patients are more likely to have a prolonged hospital stay.Disclosure: Dr. Mahmood has nothing to disclose. Dr. Ali has nothing to disclose. Dr. Chauhan has nothing to disclose. Dr. Bianchi has nothing to disclose. Dr. Singhal has received personal compensation for activities with Medicolegal, ACTION Trial Stroke, Biogen, and Dock Technologies. Dr. Singhal holds stock and/or stock options in Biogen. Dr. Singhal has received research support from Boehringer Ingel...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mahmood, S., Ali, S., Chauhan, M. A., Bianchi, N., Singhal, A., Schwamm, L. Tags: Practice, Policy, and Ethics I Source Type: research

Post-traumatic stress disorder was associated with a threefold increased risk for stroke in a Taiwanese National Health Insurance Database
ABSTRACT FROM: Chen MH, Pan TL, Li CT, et al. Risk of stroke among patients with post-traumatic stress disorder: nationwide longitudinal study. Br J Psychiatry 2015;206:302–7. What is already known on this topic People with post-traumatic stress disorder (PTSD) are more likely to have psychiatric comorbidities and cardiovascular risk factors, including diabetes mellitus, hypertension, smoking and dyslipidemia.1 2 While stroke can trigger PTSD,3 prior to this study it was not known whether PTSD increases the risk for stroke. Methods of the study This was a longitudinal follow-up study to assess for development of stro...
Source: Evidence-Based Mental Health - October 22, 2015 Category: Psychiatry & Psychology Authors: Goldfinger, J. Z. Tags: Electronic pages Source Type: research

Ezetimibe-Simvastatin Therapy Reduce Recurrent Ischemic Stroke Risks in Type 2 Diabetic Patients.
CONCLUSIONS: High potency lipid-lowering therapy effectively reduces the risk of recurrent IS in diabetic patients regardless of ATOR or EZ-SIM combination therapy. PMID: 27270238 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - June 5, 2016 Category: Endocrinology Authors: Liu CH, Chen TH, Lin MS, Hung MJ, Chung CM, Cherng WJ, Lee TH, Lin YS Tags: J Clin Endocrinol Metab Source Type: research

Obstructive Sleep Apnea is Associated with Improved Ischemic Stroke Outcomes (P4.312)
Conclusions:Among inpatients diagnosed with IS, OSA was associated with lower odds of death and poor discharge status. Consistent with animal studies, ischemic preconditioning could be a mechanism by which OSA leads to better outcomes after stroke in humans.Disclosure: Dr. Low has nothing to disclose. Dr. Elkind has received personal compensation in an editorial capacity for Neurology.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Low, D., Elkind, M. Tags: Neuroepidemiology: Cerebrovascular Disease II Source Type: research

Cardiovascular Outcomes of Vildagliptin in Patients with Type 2 Diabetes Mellitus after Acute Coronary Syndrome or Acute Ischemic Stroke
ConclusionsAmong patients with T2DM after a recent ACS or AIS, treatment with vildagliptin was not associated with increased risks of CV death, nonfatal MI, nonfatal stroke, and hospitalization for HF.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - May 21, 2019 Category: Endocrinology Authors: Dong ‐Yi Chen, Yan‐Rong Li, Chun‐Tai Mao, Chi‐Nan Tseng, I‐Chang Hsieh, Ming‐Jui Hung, Pao‐Hsien Chu, Chao‐Hung Wang, Ming‐Shien Wen, Wen‐Jin Cherng, Tien‐Hsing Chen Tags: Original Article Source Type: research

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