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Potential association between bacterial infections and ischemic stroke based on fifty case-control studies: A systematic review and meta-analysis
CONCLUSIONS: In this meta-analysis, a significant relationship was observed between infection by three bacteria such as C. pneumoniae, H. pylori, and M. tuberculosis with the occurrence of ischemic stroke. Furthermore, due to the similarity between TLRVYK domain in β2-glycoprotein-I and TLRVYK peptide in various of microorganisms, produced antibodies against pathogens interact with β2-glycoprotein-I, hence the cross-reaction phenomenon increases the positive relationship between infectious diseases and ischemic stroke.PMID:35592534 | PMC:PMC9112101 | DOI:10.1016/j.nmni.2022.100980
Source: Atherosclerosis - May 20, 2022 Category: Cardiology Authors: M Keikha M Karbalaei Source Type: research

Janssen Highlights Continued Commitment to Cardiovascular & Metabolic Healthcare Solutions with Late-Breaking Data at the First Fully Virtual American College of Cardiology Scientific Session
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to Tweet: Jan...
Source: Johnson and Johnson - March 20, 2020 Category: Pharmaceuticals Source Type: news

Level of Agreement and Factors Associated With Discrepancies Between Nationwide Medical History Questionnaires and Hospital Claims Data.
Conclusions: Detailed patient characteristics that had an impact on information bias were identified through the differing levels of agreement. PMID: 29020761 [PubMed - in process]
Source: Journal of Preventive Medicine and Public Health - October 14, 2017 Category: International Medicine & Public Health Tags: J Prev Med Public Health Source Type: research

The Emergence of Non-communicable Disease in Indonesia.
Authors: Purnamasari D Abstract Based on data from the Indonesian Ministry of Health Information Center, the estimated population of Indonesia in 2016 was approximately 258,704,986 people, consisted of 129,988,690 men and 128,716,296 women. This number of Indonesian population represents young population since the proportion of population aged 0-14 years is more than that aged >14 years. Meanwhile, the proportion of population aged 50 years and above is significantly reduced, which is thought to be due to high mortality rate in the middle-aged population. The mortality rate in  Indonesia is dominated by non-com...
Source: Acta medica Indonesiana - January 13, 2019 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe
Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies with the aim to identify populations that could potentially benefit from booster vaccinations. Methods We performed a systematic literature review and meta-analysis to investigate the role of underlying medical conditions as prognostic factors for adverse outcomes due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including death, hospitalisation, intensive c...
Source: European Respiratory Review - November 2, 2022 Category: Respiratory Medicine Authors: Vardavas, C. I., Mathioudakis, A. G., Nikitara, K., Stamatelopoulos, K., Georgiopoulos, G., Phalkey, R., Leonardi-Bee, J., Fernandez, E., Carnicer-Pont, D., Vestbo, J., Semenza, J. C., Deogan, C., Suk, J. E., Kramarz, P., Lamb, F., Penttinen, P. Tags: Respiratory infections and tuberculosis Reviews Source Type: research

Association Between Average Daily Television Viewing Time and Chronic Obstructive Pulmonary Disease-Related Mortality: Findings From the Japan Collaborative Cohort Study.
CONCLUSIONS: Avoiding a sedentary lifestyle, particularly prolonged TV viewing, may help in preventing death from COPD among men. PMID: 25947581 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - May 9, 2015 Category: Epidemiology Tags: J Epidemiol Source Type: research

A Rare Case of Central Nervous System Tuberculosis Presenting as Transient Splenial Lesion: Case Report and Literature Review (P1.320)
Conclusions:Based on literature review, the transient splenial lesion of corpus callosum has never been reported in patients with CNS tuberculosis. The mechanisms underlying transient splenial lesions may due to intramyelinic edema and inflammatory cell infiltration. This hypothesis supported by the MR spectroscopy findings in our patient. Since early diagnosis and treatment can reduce mortality and morbidity, patients with isolated splenial lesion warrant diagnostic tests for CNS tuberculosis.Study Supported by:The authors report no disclosures relevant to the manuscript.Disclosure: Dr. Wu has nothing to disclose. Dr. Che...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wu, J.-W., Chen, S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research

The prevalence of Chronic Obstructive Pulmonary Disease (COPD) in Sri Lanka:outcome of the BOLD study
Conclusion: The prevalence of COPD in Sri Lankan adults is similar to global and regional prevalences.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Amarasiri, L., Gunasinghe, W., Sadikeen, A., Fernando, A., Madegedara, D., Wickramasinghe, R., Gunasekera, K. Tags: Epidemiology Source Type: research

91-Year-Old Man With Upper Extremity Ecchymoses
A 91-year-old man with a medical history significant for previous ischemic stroke, tuberculosis status post lung resection, and type 2 diabetes mellitus presented to his primary care physician with extensive non-traumatic bruising of the bilateral upper extremities.
Source: Mayo Clinic Proceedings - February 29, 2020 Category: Internal Medicine Authors: Ryan B. Khodadadi, John R. Ogden, Ariela L. Marshall Tags: Residents ’ clinic Source Type: research

Hypertension is associated with increased mortality in patients with tuberculosis in Guinea-Bissau
Tuberculosis (TB) continues to be a major health problem in low- and middle-income countries (LMICs). In 2019, WHO estimated that there were 10 million new cases of TB, and 1.4 million deaths due to TB worldwide (World Health Organization, 2020). At the same time, LMICs face a rapid increase in the burden of noncommunicable diseases such as diabetes mellitus (DM) and cardiovascular diseases (CVD), including coronary heart disease and stroke. More than 75% of cardiovascular deaths occur in LMICs (World Health Organization, 2014).
Source: International Journal of Infectious Diseases - July 2, 2021 Category: Infectious Diseases Authors: Anneline B Seegert, Cecilie B Patsche, Armando Sifna, Victor F Gomes, Christian Wejse, Merete Storgaard, Frauke Rudolf Source Type: research