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Condition: Dementia
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Total 430 results found since Jan 2013.
Bilingualism delays the onset of behavioural but not aphasic forms of Frontotemporal Dementia
Publication date: Available online 18 March 2017 Source:Neuropsychologia Author(s): Suvarna Alladi, Thomas H. Bak, Mekala Shailaja, Divyaraj Gollahalli, Amuya Rajan, Bapiraju Surampudi, Michael Hornberger, Vasanta Duggirala, Jaydip Ray Chaudhuri, Subhash Kaul Bilingualism has been found to delay onset of dementia and this has been attributed to an advantage in executive control in bilinguals. However, the relationship between bilingualism and cognition is complex, with costs as well as benefits to language functions. To further explore the cognitive consequences of bilingualism, the study used Frontotemporal dementia (FTD...
Source: Neuropsychologia - March 17, 2017 Category: Neurology Source Type: research
The mediational role of physical activity, social contact and stroke on the association between age, education, employment and dementia in an Asian older adult population
Our study aimed to investigate the pathways by which socio-demographic factors, modifiable health and lifestyle risk factors influence each other, and subsequently, lead to dementia.
Source: BMC Psychiatry - March 20, 2017 Category: Psychiatry Authors: Edimansyah Abdin, Siow Ann Chong, Chao Xu Peh, Janhavi Ajit Vaingankar, Boon Yiang Chua, Swapna Verma, Anitha Jeyagurunathan, Saleha Shafie and Mythily Subramaniam Source Type: research
Bilingualism delays the onset of behavioral but not aphasic forms of frontotemporal dementia
Publication date: May 2017 Source:Neuropsychologia, Volume 99 Author(s): Suvarna Alladi, Thomas H. Bak, Mekala Shailaja, Divyaraj Gollahalli, Amuya Rajan, Bapiraju Surampudi, Michael Hornberger, Vasanta Duggirala, Jaydip Ray Chaudhuri, Subhash Kaul Bilingualism has been found to delay onset of dementia and this has been attributed to an advantage in executive control in bilinguals. However, the relationship between bilingualism and cognition is complex, with costs as well as benefits to language functions. To further explore the cognitive consequences of bilingualism, the study used Frontotemporal dementia (FTD) syndromes...
Source: Neuropsychologia - March 20, 2017 Category: Neurology Source Type: research
Differential Associations of Socioeconomic Status With Global Brain Volumes and White Matter Lesions in African American and White Adults: the HANDLS SCAN Study
Objective: The aim of the study was to examine interactive relations of race and socioeconomic status (SES) to magnetic resonance imaging (MRI)–assessed global brain outcomes with previously demonstrated prognostic significance for stroke, dementia, and mortality.
Methods: Participants were 147 African Americans (AAs) and whites (ages 33–71 years; 43% AA; 56% female; 26% below poverty) in the Healthy Aging in Neighborhoods of Diversity across the Life Span SCAN substudy. Cranial MRI was conducted using a 3.0 T unit. White matter (WM) lesion volumes and total brain, gray matter, and WM volumes were computed. An SES com...
Source: Psychosomatic Medicine - April 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research
Elevated cerebrospinal fluid total Tau levels reflects predominant cortical involvement in Alzheimers disease (P1.093)
Conclusions:Elevated CSF Tau levels in AD patients could be surrogate biomarker for AD subtypes with predominant early cortical symptoms and atrophy. There is a need for a systematic prospective unbiased follow-up to see if rapid clinical progression in AD is related to elevated T-Tau and distinct AD subtypes.Disclosure: Dr. Pillai has nothing to disclose. Dr. Khrestian has nothing to disclose. Dr. Bekris has nothing to disclose. Dr. Safar has nothing to disclose. Dr. Leverenz has received personal compensation for activities with Axovant, GE Healthcare and Navidea Biopharmaceuticals as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pillai, J., Khrestian, M., Bekris, L., Safar, J., Leverenz, J. Tags: Aging and Dementia: Biomarkers Source Type: research
Predictive Variables of Cognitive Dysfunction in Patients with Lupus (P1.340)
Conclusions:Duration of disease and low educational level are predictors of CD in patients with SLE. Depression and anxiety did not influence cognitive performance. Although cardiovascular comorbidity is a risk factor for dementia in general population, those variables might play a minor role in SLE patients.Study Supported by:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and São Paulo Research Foundation (FAPESP) (grant #2015/08833-7) supported this study.Disclosure: Dr. Alessi has nothing to disclose. Dr. Dutra Antonio has nothing to disclose. Dr. Maria has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alessi, H., Dutra, L. A., Maria, L., Xavier, P., Couce, P., Kayser, C., Barsottini, O. Tags: CNS Inflammatory Diseases and Differential Diagnosis I Source Type: research
Association between frequency of sleep medication use and brain morphology (P3.058)
Conclusions:This is the first study to examine the association between frequency of sleep medication use and brain morphology in a healthy group of older adults. Metabolic effects or a possible neurotoxicity could play a role to the observed associations.Study Supported by:NIH R01AG038465-02NIH R01AG026158-07Research programs of excellence IKY/SIEMENS for Angeliki Tsapanou, Nikolao ScarmeaDisclosure: Dr. Tsapanou has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Haider has nothing to disclose. Dr. Stern has received personal compensation for activities with Takeda, Axovant, and Eli Lilly and Company as an adviso...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tsapanou, A., Gu, Y., Haider, L., Sakhardande, J., Scarmeas, N., Stern, Y. Tags: Sleep Disruption and Medical Co-Morbidities Source Type: research
HELIAD study: Dementia prevalence in Greece (P3.095)
Conclusions:The prevalence of dementia and its subtypes in Greece is similar or at the lower range of that reported in many other European countries and globally. In our sample, increased age and decreased level of education status, but not gender, were predictive of a diagnosis of dementia with age being the strongest predictive factor.Study Supported by:Funding/Support: IIRG-09-133014 from the Alzheimer’s Association; 189 10276/8/9/2011 from the ESPA-EU program Excellence Grant (ARISTEIA) which is co-funded by the European Social Fund and Greek National resources; and Y2β/o.51657/14.4.2009 from the Ministry fo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Sakka, P., Kosmidis, M., Yannakoulia, M., Dardiotis, E., Hadjigeorgiou, G., Scarmeas, N. Tags: Aging and Dementia: Epidemiologic Studies Source Type: research
A Brief Dementia Screening Test in South Africa: Results from the Health and Aging Longitudinal Study of an INDEPTH community (HAALSI) (P4.191)
Conclusions:There is a potentially protective and long-lasting impact of secondary school education on cognitive status later in life in this setting. Using a brief screening test in this relatively poor cohort of older South Africans, patterns of low cognition are similar to those in the USA and other countries.Study Supported by:The National Institute on Aging at the National Institute of Health (NIH) (1P01AG041710-01A1; 1R01AG051144–01; 3U54HG006938-03S1). F. Mateen is supported by a subgrant of P30AG024409 from the NIH for the Harvard Center for Global Demography and Aging. The Agincourt HDSS was supported by the...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mateen, F., Jennings, E., Montana, L., Wagner, R., Kahn, K., Tollman, S., Berkman, L. Tags: Behavioral and Cognitive Neurology: Neurodegenerative Disorders Source Type: research
MCI subtypes are heterogeneous and preceded by different risk factors: A study on aMCI and naMCI incidence (P4.194)
Conclusions:Results suggested that aMCI and naMCI are inherently heterogeneous from the outset, illustrated by their different risk factors. Recognizing indicators of MCI prior to clinical presentation is critical in targeted interventions, early treatment, and prevention from rapid progression to dementia.Study Supported by:NIA grant: AG03949Sylvia and Leonard Marx FoundationDisclosure: Dr. Zammit has nothing to disclose. Dr. Lipton has received personal compensation from Allergan, American Headache Society, Autonomic Technologies, Boston Scientific, Bristol Myers Squibb, Cognimed, Colucid, Eli Lilly, eNeura Therapeutics,...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Zammit, A., Lipton, R., Katz, M., Derby, C., Hall, C. Tags: Behavioral and Cognitive Neurology: Neurodegenerative Disorders Source Type: research
Predictive indices for functional improvement and deterioration, institutionalization, and death among elderly Medicare beneficiaries
Conclusion Predictive indices, or point and scoring systems used to predict outcomes, can identify elderly Medicare beneficiaries at risk of functional deterioration, institutionalization, and death and can aid policy makers, clinicians, and family members in improving care for older adults and supporting successful aging in the community.
Source: PMandR - April 27, 2017 Category: Rehabilitation Source Type: research
Integrating Health Promotion Into Physical Therapy Practice to Improve Brain Health and Prevent Alzheimer Disease.
This article discusses prevention, prediction, plasticity, and participation in the context of preserving brain health and preventing Alzheimer disease and related dementias in aging adults.
RECOMMENDATIONS FOR CLINICAL PRACTICE: Rehabilitation professionals have opportunities to slow disease progression through research, practice, and education initiatives. From a clinical perspective, interventions that target brain health through lifestyle changes and exercise interventions show promise for preventing stroke and associated neurovascular diseases in addition to dementia. Physical therapists are well positioned to in...
Source: Physical Therapy - June 20, 2017 Category: Physiotherapy Authors: McGough E, Kirk-Sanchez N, Liu-Ambrose T Tags: J Neurol Phys Ther Source Type: research
The 2017 hormone therapy position statement of The North American Menopause Society
Abstract: The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence. The Panel's recommendations were reviewed and a...
Source: Menopause - June 27, 2017 Category: OBGYN Tags: Position Statement Source Type: research
Snoring link to Alzheimer ’s disease unproven
Conclusion
This relatively large cross-sectional analysis has found a link between certain measures of breathing problems during sleep and poorer cognitive function in middle-aged to older adults.
The strengths of this study include its size and use of a prospective sleep study to assess whether people had sleep apnoea or other problems with breathing during sleep. The use of standard cognitive tests is also a strength.
However, the study does have its limitations:
The study did have mixed findings – while certain measures of problems with breathing during sleep (e.g. oxygen levels) were associated with cognitive outco...
Source: NHS News Feed - July 24, 2017 Category: Consumer Health News Tags: Neurology Lifestyle/exercise Source Type: news
Association between vitamin D deficiency and heart failure risk in the elderly
ConclusionsThere was a high prevalence of vitamin D deficiency in the elderly, and the evidence shows a strong association between vitamin D deficiency and increased risk of heart failure in this population.
Source: ESC Heart Failure - August 1, 2017 Category: Cardiology Authors: Catarina Magalh ães Porto, Vanessa De Lima Silva, João Soares Brito Luz, Brivaldo Markman Filho, Vera Magalhães Silveira Tags: Original Research Article Source Type: research
