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Condition: Liver Disease
Procedure: Ultrasound
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Total 1155 results found since Jan 2013.
A randomized placebo-controlled, double-blind study to investigate the effect of a high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients, new insights on serum STAT-3 and hepassocin
CONCLUSIONS: Cholecalciferol is recommended as additional therapy to modulate lipid peroxidation and systemic inflammation alongside other NAFLD therapies.PMID:37667938 | DOI:10.26355/eurrev_202308_33413
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: S J Alarfaj M M Bahaa H A Yassin E El-Khateeb F A Kotkata M A El-Gammal A I Elberri E Habba E E Zien El-Deen M O Khrieba T A El-Masry W A Negm E I Elberri Source Type: research
The benefit of metformin in the treatment of pediatric non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials
Conclusion: According to the data of this meta-analysis, treatment with metformin failed to statistically improve liver enzymes but may be beneficial in the improvement of lipid parameters and insulin metabolism regulation in pediatric patients with NAFLD. As there are not enough available studies in the literature, the influence of metformin on liver ultrasonography or histology in pediatric NAFLD should be further analyzed in future studies.What is Known:• Lifestyle modification with weight loss through physical activity and dietary modification is the recommended treatment option for pediatric NAFLD.• Metformin may ...
Source: European Journal of Pediatrics - August 28, 2023 Category: Pediatrics Source Type: research
Liver Fat Storage Is a Better Predictor of Coronary Artery Disease than Visceral Fat
This study measured associations among visceral fat storage, fatty liver, insulin resistance, atherosclerosis, and CAD. Patients were divided into three groups: excess visceral fat (visceral fat area >330 ± 99 cm2), non-alcoholic fatty liver disease (NAFLD), and a control group. The definition of fatty liver is liver minus spleen density greater than or equal to -10. We defined early atherosclerosis as intima-media thickness of the common carotid artery >7 mm in men and >0.65 mm in women, measured with Doppler ultrasound. Visceral fat area was defined using CT (>330 ± 99 cm2). Insulin-resistance biomarkers (H...
Source: Atherosclerosis - August 25, 2023 Category: Cardiology Authors: Maamoun Basheer Elias Saad Helena Jeries Nimer Assy Source Type: research
Impact of HBV infection on clinical outcomes in patients with metabolic dysfunction-associated fatty liver disease
CONCLUSIONS: The large population-based study revealed chronic HBV infection increases the overall risk of liver fibrosis, but protects from atherosclerosis in patients with MAFLD.IMPACT AND IMPLICATIONS: Patients with metabolic-associated fatty liver disease can also be coinfected with chronic HBV. Concomitant HBV infection increases the overall risk of liver fibrosis, but protects from atherosclerosis in patients with MAFLD.PMID:37600956 | PMC:PMC10432217 | DOI:10.1016/j.jhepr.2023.100836
Source: Atherosclerosis - August 21, 2023 Category: Cardiology Authors: Yu-Ming Cheng Tsung-Han Hsieh Chia-Chi Wang Jia-Horng Kao Source Type: research
Comparison of the severity of metabolic, liver and cardiovascular damage in NAFLD patients attending the hepatology clinic over the last three decades
CONCLUSION: Over the past 10 years compared to previous decades, NAFLD patients presented to observation with more severe liver disease and subclinical atherosclerosis, paralleling the spread of diabetes and obesity. PNPLA3 unfavorable genotype became more prevalent over time.PMID:37507284 | DOI:10.1016/j.dld.2023.07.009
Source: Atherosclerosis - July 28, 2023 Category: Cardiology Authors: Rosa Lombardi Lucia Colavolpe Francesca Alletto Annalisa Cespiati Erika Fatta Cristina Bertelli Felice Cinque Giuseppina Pisano Edoardo Pulixi Paolo Francione Gabriele Maffi Federica Iuculano Paola Dongiovanni Larry Burdick Daniela Bignamini Marco Maggion Source Type: research
Residual burden of liver disease after HCV clearance in hemophilia: a word of caution in the era of gene therapy
Blood Adv. 2023 Jul 28:bloodadvances.2023010723. doi: 10.1182/bloodadvances.2023010723. Online ahead of print.ABSTRACTRuling out advanced fibrosis/cirrhosis is mandatory for persons with hemophilia (PWH) who are candidate to gene therapy. However, clinical evaluation and non-invasive tests may be inaccurate after HCV clearance. We conducted a prospective hepatological screening to detect advanced fibrosis/cirrhosis in PWH after HCV clearance. Any risk factor of chronic liver damage was registered by using biochemical data, liver stiffness measurement (LSM) and ultrasound (US). A pre/post HCV clearance analysis was prospect...
Source: Adv Data - July 28, 2023 Category: Epidemiology Authors: Vincenzo La Mura Niccol ò Bitto Cecilia Capelli Camilla Caputo Simona Maria Siboni Sara Arcudi Alessandro Ciavarella Roberta Gualtierotti Anna Ludovica Fracanzani Angelo Sangiovanni Flora Peyvandi Source Type: research
Novel predictors of early atherosclerosis in nonalcoholic fatty liver disease
CONCLUSIONS: Serum endocan levels, MPV and CIMT could be considered as good predictors of endothelial dysfunction and therefore early detection of subclinical atherosclerosis in NAFLD patients.PMID:37502438 | PMC:PMC10369661 | DOI:10.5114/ceh.2023.127466
Source: Atherosclerosis - July 28, 2023 Category: Cardiology Authors: Badawy Abdulkhalik Abdulaziz Ahmed Mahmoud Bendary Aida Thabet Eman Gamal Behery Mona Salah Medhat A Khalil Ghadeer Rashad Source Type: research
Residual burden of liver disease after HCV clearance in hemophilia: a word of caution in the era of gene therapy
Blood Adv. 2023 Jul 28:bloodadvances.2023010723. doi: 10.1182/bloodadvances.2023010723. Online ahead of print.ABSTRACTRuling out advanced fibrosis/cirrhosis is mandatory for persons with hemophilia (PWH) who are candidate to gene therapy. However, clinical evaluation and non-invasive tests may be inaccurate after HCV clearance. We conducted a prospective hepatological screening to detect advanced fibrosis/cirrhosis in PWH after HCV clearance. Any risk factor of chronic liver damage was registered by using biochemical data, liver stiffness measurement (LSM) and ultrasound (US). A pre/post HCV clearance analysis was prospect...
Source: Adv Data - July 28, 2023 Category: Epidemiology Authors: Vincenzo La Mura Niccol ò Bitto Cecilia Capelli Camilla Caputo Simona Maria Siboni Sara Arcudi Alessandro Ciavarella Roberta Gualtierotti Anna Ludovica Fracanzani Angelo Sangiovanni Flora Peyvandi Source Type: research
Information Entropy and Its Applications
Adv Exp Med Biol. 2023;1403:153-167. doi: 10.1007/978-3-031-21987-0_8.ABSTRACTUltrasound is a first-line diagnostic tool for imaging many disease states. A number of statistical distributions have been proposed to describe ultrasound backscattering measured from tissues having different disease states. As an example, in this chapter we use nonalcoholic fatty liver disease (NAFLD), which is a critical health issue on a global scale, to demonstrate the capabilities of ultrasound to diagnose disease. Ultrasound interaction with the liver is typically characterized by scattering, which is quantified for the purpose of determin...
Source: Adv Data - July 26, 2023 Category: Epidemiology Authors: Po-Hsiang Tsui Source Type: research
Prevalence and clinical outcomes in subtypes of metabolic associated fatty liver disease
CONCLUSION: This population-based study proves the concept that subtypes of MAFLD can help risk stratification of clinical outcomes.PMID:37491179 | DOI:10.1016/j.jfma.2023.07.010
Source: J Formos Med Assoc - July 25, 2023 Category: General Medicine Authors: Kun-Lin Cheng Shao-Wen Wang Yu-Ming Cheng Tsung-Han Hsieh Chia-Chi Wang Jia-Horng Kao Source Type: research
Clinical Practice Guidelines For the Management of Hepatocellular Carcinoma: A Systematic Review
ConclusionsThe included CPGs provided a comprehensive approach, emphasizing the evaluation of risk factors, utilization of the BCLC staging system, and the importance of a multidisciplinary approach. Regular surveillance using ultrasound for cirrhotic patients was widely recommended. An understanding of contemporary international CPGs can prioritize aspects of the management of HCC to assist healthcare professionals to develop a national guideline to enable standardized, comprehensive, and evidence-based care for patients with HCC.
Source: Journal of Gastrointestinal Cancer - July 22, 2023 Category: Cancer & Oncology Source Type: research
