• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Evaluation of bronchial wall thickness in asthma using magnetic resonance imaging
Conclusions We have demonstrated that MRI-UTE is an accurate and reliable radiation-free method to assess bronchial wall dimensions in asthma, with enough spatial resolution to differentiate severe from non-severe asthma.
Source: European Respiratory Journal - December 31, 2021 Category: Respiratory Medicine Authors: Benlala, I., Dournes, G., Girodet, P.-O., Benkert, T., Laurent, F., Berger, P. Tags: Lung imaging, Asthma and allergy Original Articles: Asthma and imaging Source Type: research

Peripheral and proximal lung ventilation in asthma: Short-term variation and response to bronchodilator inhalation
The relative involvement of the large and small airways in asthma is not clear. Hyperpolarized gas magnetic resonance imaging (MRI) provides high-resolution 3-dimensional images of ventilation distribution that can be quantified by the ventilated volume percentage (VV%) of the lungs.
Source: Journal of Allergy and Clinical Immunology - December 9, 2020 Category: Allergy & Immunology Authors: Helen Marshall, J. Chris Kenworthy, Felix C. Horn, Steven Thomas, Andrew J. Swift, Salman Siddiqui, Christopher E. Brightling, Jim M. Wild Source Type: research

129Xe MRI as a measure of clinical disease severity for pediatric asthma
Measurement of regional lung ventilation with hyperpolarized 129Xe magnetic resonance imaging (129Xe MRI) in pediatric asthma is poised to advance our understanding of disease mechanisms and pathophysiology in a disorder with diverse clinical phenotypes. 129Xe MRI has not been investigated in a pediatric asthma cohort.
Source: Journal of Allergy and Clinical Immunology - November 19, 2020 Category: Allergy & Immunology Authors: Nancy Y. Lin, David J. Roach, Matthew M. Willmering, Laura L. Walkup, Md Monir Hossain, Priyanka Desirazu, Zackary I. Cleveland, Theresa W. Guilbert, Jason C. Woods Source Type: research

The use of magnetic resonance imaging in differential diagnosis of allergic fungal sinusitis and eosinophilic mucin rhinosinusitis.
Conclusions: MRI features are key to the differential diagnosis of AFS and EMRS. PMID: 31559063 [PubMed]
Source: Journal of Thoracic Disease - September 28, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Dismantling the pathophysiology of asthma using imaging
Asthma remains an important disease worldwide, causing high burden to patients and healthcare systems and presenting a need for better management and ultimately prevention and cure. Asthma is a very heterogeneous condition, with many different pathophysiological processes. Better measurement of those pathophysiological processes are needed to better phenotype disease, and to go beyond the current, highly limited measurements that are currently used: spirometry and symptoms. Sophisticated three-dimensional lung imaging using computed tomography and ventilation imaging (single photon emission computed tomography and positron...
Source: European Respiratory Review - April 16, 2019 Category: Respiratory Medicine Authors: King, G. G., Farrow, C. E., Chapman, D. G. Tags: Lung imaging, Asthma and allergy Dismantling Airway Disease Source Type: research

Gadolinium induced anaphylaxis with positive skin tests
Gadolinium is a heavy metal element with paramagnetic properties used as contrast in Magnetic Resonance Imaging (MRI) studies. There are nine types of gadolinium-based contrast agents (GBCAs), that may be classified as ionic or nonionic and linear or macrocyclic.1 Hypersensitivity reactions (HSR) to GBCAs are uncommon (0.004 to 0.7%), but anaphylaxis (0.001 to 0.01%2) and fatalities have occurred. These less frequent acute reactions were once considered non-immunological. However, there are few case reports implicating an IgE-dependent allergic mechanism.
Source: Annals of Allergy, Asthma and Immunology - March 25, 2019 Category: Allergy & Immunology Authors: Guillermo Rodriguez-Nava, Alex M. Kesler, Ismael Carrilo-Martin, Alexei Gonzalez-Estrada Tags: Letters Source Type: research

Gadolinium-induced anaphylaxis with positive skin test results
Gadolinium is a heavy metal element with paramagnetic properties used as contrast in magnetic resonance imaging (MRI) studies. There are 9 types of gadolinium-based contrast agents (GBCAs), which can be classified as ionic or nonionic and linear or macrocyclic.1 Hypersensitivity reactions (HSRs) to GBCAs are uncommon (0.004%-0.7%), but anaphylaxis (0.001%-0.01%2) and fatalities have occurred. These less frequent acute reactions were once considered nonimmunologic. However, there are few case reports that implicate an IgE-dependent allergic mechanism.
Source: Annals of Allergy, Asthma and Immunology - March 25, 2019 Category: Allergy & Immunology Authors: Guillermo Rodriguez-Nava, Alex M. Kesler, Ismael Carrillo-Martin, Alexei Gonzalez-Estrada Tags: Letter Source Type: research

An Ounce of Caution: Superparamagnetic Iron Oxide Nanoparticle Based MRI Contrast Associated Anaphylaxis
Superparamagnetic iron oxide nanoparticles (SPIONs) are increasingly utilized alternatives to gadolinium-based Magnetic Resonance Imaging (MRI) contrast agents in the diagnosis of osteomyelitis in diabetic patients with renal failure [1]. Ferumoxytol is approved by the United States Food and Drug Administration (FDA), the European Medicines Agency, for intravenous (IV) use for iron replacement therapy [1-3]. Ferumoxytol is composed of an iron-carbohydrate complex that minimizes dissociation and appearance of free iron into the serum.
Source: Annals of Allergy, Asthma and Immunology - November 12, 2018 Category: Allergy & Immunology Authors: Alexander J. Heckman, Anjali Agarwal, Keith A. Sacco, Brett T. Hiroto, Pramod K. Guru Tags: Letters Source Type: research

An ounce of caution
Superparamagnetic iron oxide nanoparticles are increasingly used alternatives to gadolinium-based magnetic resonance imaging (MRI) contrast agents in the diagnosis of osteomyelitis in diabetic patients with renal failure.1 Ferumoxytol is approved by the United States Food and Drug Administration and the European Medicines Agency for intravenous use for iron replacement therapy.1 –3 Ferumoxytol is composed of an iron–carbohydrate complex that minimizes dissociation and appearance of free iron into the serum.
Source: Annals of Allergy, Asthma and Immunology - November 12, 2018 Category: Allergy & Immunology Authors: Alexander J. Heckman, Anjali Agarwal, Keith A. Sacco, Brett T. Hiroto, Pramod K. Guru Tags: Letters Source Type: research

Clinical characteristics of adverse reaction to radiocontrast media in children: a single center experience
Radiocontrast media are used widely in medical imaging to improve the diagnostic accuracy. However, studies on the adverse reaction of radiocontrast media in children are limited. We aimed to describe the characteristics of adverse reactions to radiocontrast media among children who had a computed tomography scan or magnetic resonance imaging in a tertiary university hospital.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2018 Category: Allergy & Immunology Authors: M. Kim, B. Lee, Y. Choi, D. Suh Tags: P003 Source Type: research

Ventilation defect percent in helium-3 magnetic resonance imaging as a biomarker of severe outcomes in asthma
Imaging tools are of increasing interest in assessing patients with asthma for receipt of personalized therapy. Hyperpolarized (HP) 3He magnetic resonance imaging (MRI) of the lungs is one example of a functional lung imaging method that provides reproducible regional detection of ventilation defects in asthma.1 These ventilation defects are associated with areas of airway obstruction and air trapping.2 The most common metric for measuring defect extent is the ventilation defect percent (VDP).2-4 Here, we measure VDP using HP 3He MRI and compare VDP to asthma outcomes indicative of severe exacerbation, analogous to similar...
Source: Journal of Allergy and Clinical Immunology - November 9, 2017 Category: Allergy & Immunology Authors: David G. Mummy, Stanley J. Kruger, Wei Zha, Ronald L. Sorkness, Nizar N. Jarjour, Mark L. Schiebler, Loren C. Denlinger, Michael D. Evans, Sean B. Fain Tags: Letter to the Editor Source Type: research

Using imaging as a biomarker for asthma
There have been significant advancements in the various imaging techniques being used for the evaluation of asthmatic patients, both from a clinical and research perspective. Imaging characteristics can be used to identify specific asthmatic phenotypes and provide a more detailed understanding of endotypes contributing to the pathophysiology of the disease. Computed tomography, magnetic resonance imaging, and positron emission tomography can be used to assess pulmonary structure and function. It has been shown that specific airway and lung density measurements using computed tomography correlate with clinical parameters, i...
Source: Journal of Allergy and Clinical Immunology - December 31, 2016 Category: Allergy & Immunology Authors: Abhaya Trivedi, Chase Hall, Eric A. Hoffman, Jason C. Woods, David S. Gierada, Mario Castro Tags: Reviews and feature article Source Type: research

Clinical potential for imaging in patients with asthma and other lung disorders
The ability of lung imaging to phenotype patients, determine prognosis, and predict response to treatment is expanding in clinical and translational research. The purpose of this perspective is to describe current imaging modalities that might be useful clinical tools in patients with asthma and other lung disorders and to explore some of the new developments in imaging modalities of the lung. These imaging modalities include chest radiography, computed tomography, lung magnetic resonance imaging, electrical impedance tomography, bronchoscopy, and others.
Source: Journal of Allergy and Clinical Immunology - November 17, 2016 Category: Allergy & Immunology Authors: Emily M. DeBoer, David R. Spielberg, Alan S. Brody Tags: Reviews and feature article Source Type: research

Journal Allergy & Clinical Immunology Perspective: Clinical potential for imaging in asthma and other lung disorders
The ability of lung imaging to phenotype patients, determine prognosis, and to predict response to treatments is expanding in clinical and translational research. The purpose of this perspective is to describe current imaging modalities that may be useful clinical tools in asthma and other lung disorders and to explore some of the new developments in imaging modalities of the lung. These imaging modalities include chest radiography (CXR), computed tomography (CT), lung magnetic resonance imaging (MRI), electrical impedance tomography (EIT), bronchoscopy, and others.
Source: Journal of Allergy and Clinical Immunology - November 17, 2016 Category: Allergy & Immunology Authors: Emily M. DeBoer, David R. Spielberg, Alan S. Brody Source Type: research

Pages: 1  2