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Condition: Chronic Obstructive Pulmonary

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Total 1666 results found since Jan 2013.

Virtual Teach-To-Goal ™ Adaptive Learning of Inhaler Technique for Inpatients with Asthma or COPD
Conclusions This study is the first to demonstrate the efficacy of adaptive V-TTG™ learning to teach the inhaler technique. V-TTG™ improved most participants' technique to an acceptable level, reached mastery for half, and also increased self-efficacy and actualized skill. V-TTG™ has potential to improve health care across care transitions.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 5, 2017 Category: Allergy & Immunology Source Type: research

Radiographic Evidence of Sinonasal Inflammation in Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: An Underrecognized Association
Conclusions Radiographic evidence of sinonasal inflammation was a common comorbidity in ACOS. Future studies are required to examine the role of sinonasal inflammation in ACOS.
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 29, 2017 Category: Allergy & Immunology Source Type: research

Developing a Virtual Teach-To-Goal ™ Inhaler Technique Learning Module: A Mixed Methods Approach
Conclusions V-TTG™ is a promising educational tool for improving patients' inhaler technique, iteratively developed and refined with patient input. Patients in our urban, academic hospital overwhelmingly reported access to platforms and willingness to use V-TTG™ for health education.
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 7, 2017 Category: Allergy & Immunology Source Type: research

Consensus Document on Home Nebulization for Maintenance Treatment of Obstructive Airway Diseases: A Joint Initiative by the National Allergy Asthma Bronchitis Institute (NAABI) and Chest Research Foundation (CRF).
This article presents the findings of the consensus panel on the use of maintenance treatment of OADs with nebulization at home. PMID: 28598050 [PubMed - in process]
Source: Journal of the Association of Physicians of India - June 11, 2017 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Asthma Morbidity, Comorbidities, and Modifiable Factors among Older Adults
Conclusions Among older adults, asthma-related hospitalizations and ED/UCV were associated with clinical comorbidities, mold in the home, and financial barriers to asthma-related health care. Interventions addressing modifiable factors could reduce asthma morbidity among older adults.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 26, 2017 Category: Allergy & Immunology Source Type: research

Allergy and Chronic Obstructive Pulmonary Disease.
PMID: 28836543 [PubMed - in process]
Source: Chinese Medical Journal - August 26, 2017 Category: General Medicine Authors: Jin JM, Sun YC Tags: Chin Med J (Engl) Source Type: research

Increasing our knowledge base of asthma
During the past decade, there has been an explosion in our knowledge of asthma. There are new descriptions of phenotypes, endotypes, and even genotypes. New approaches to management have been and continue to be developed. The realization and characterization of a spectrum of overlap with chronic obstructive pulmonary disease (COPD) in many patients with asthma have been reported in detail and approaches to management of patients with severe asthma continue on the forefront. These and other aspects of asthma are well represented in the more than 200 articles published on asthma since 2015 in the Annals of Allergy, Asthma and Immunology.
Source: Annals of Allergy, Asthma and Immunology - December 1, 2017 Category: Allergy & Immunology Authors: John J. Oppenheimer, Gailen D. Marshall Tags: Perspective Source Type: research

Atopy Is Associated with Age at Asthma Onset in Elderly Patients
Conclusions Most elderly asthmatic patients followed up in our tertiary center were atopic and higher values of total serum IgE suggest atopy. Atopy was inversely correlated with age of asthma onset. The diagnosis of allergic asthma in the elderly population is essential to treat patients more properly, improving their quality of life and decreasing asthma morbidity and mortality.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 16, 2017 Category: Allergy & Immunology Source Type: research

Relationship of Blood Eosinophil Count to Exacerbations in Chronic Obstructive Pulmonary Disease
Conclusions In this study, high blood eosinophil counts were an independent risk factor for future exacerbations in patients with COPD, a phenotype that might benefit from therapy directed at eosinophilic-driven disease and inflammation.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 16, 2017 Category: Allergy & Immunology Source Type: research

Asthma versus chronic obstructive pulmonary disease, the Dutch versus British hypothesis, and role of interleukin-5
Purpose of review Asthma and COPD represent heterogeneous disorders with broad ranging impact on patients and health systems. This review focuses on evidence for early attempts at understanding their pathogenesis by the British and Dutch hypotheses. It also addresses the role of eosinophils, IL-5, and biologics targeting these pathways in asthma and COPD. Recent findings Among asthma and COPD patients, clusters exist based on phenotypic and biologic markers allowing for further understanding of endotypes. Recent studies suggest the role of eosinophils and optimal therapies for each condition may be different. Summary...
Source: Current Opinion in Allergy and Clinical Immunology - December 21, 2017 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Gustavo J. Rodrigo Source Type: research

Update on questionnaires for assessing adherence to inhaler devices in respiratory patients
The objective of this review was to update information on main questionnaires used in daily for assessing adherence to inhalers of patients with chronic respiratory diseases. Recent findings The test of the adherence to inhalers (TAI) is a recently developed and validated 12-item questionnaire to assess adherence to inhalers of aerosolized drugs in patients with asthma or COPD. The instrument can easily identify nonadherence, classify the level of adherence into good, intermediate and poor, and establish three nonadherence behaviour patterns of erratic, deliberate, and unwitting, which are useful for tailoring correctiv...
Source: Current Opinion in Allergy and Clinical Immunology - December 21, 2017 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Gustavo J. Rodrigo Source Type: research

Targeting Neutrophils in Severe Asthma via Siglec-9
Severe asthma comprises only 5% of patients with asthma, but the burden it brings to the social health system accounts for more than half of all asthmatics. Clinical evidence shows that severe asthma is often linked to the recruitment and activation of neutrophils in the airways. However, the underlying molecular and immunological mechanisms of neutrophilia in severe asthma are not clear and currently available drugs exert only limited effects on neutrophilic inflammation. Great efforts are underway to address the mystery of neutrophilic inflammation in chronic respiratory disorders. Sialic acid-binding immunoglobulin-like...
Source: International Archives of Allergy and Immunology - January 5, 2018 Category: Allergy & Immunology Source Type: research

Addressing the Impact and Unmet Needs of Nonadherence in Asthma and Chronic Obstructive Pulmonary Disease: Where Do We Go From Here?
Publication date: Available online 12 January 2018 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Richard Dekhuijzen, Federico Lavorini, Omar S. Usmani, Job F.M. van Boven Nonadherence to treatment, and its associated health and economic burden, is particularly problematic in asthma and chronic obstructive pulmonary disease management because of heterogeneous patient populations and the need for an inhaled route of drug administration. Symptom variability, comorbidities, and device switching further add to suboptimal adherence rates. As opposed to controlled clinical trials, real-life studie...
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 13, 2018 Category: Allergy & Immunology Source Type: research

Asthma versus chronic obstructive pulmonary disease, the Dutch versus British hypothesis, and role of interleukin-5
Purpose of review Asthma and COPD represent heterogeneous disorders with broad ranging impact on patients and health systems. This review focuses on evidence for early attempts at understanding their pathogenesis by the British and Dutch hypotheses. It also addresses the role of eosinophils, IL-5, and biologics targeting these pathways in asthma and COPD. Recent findings Among asthma and COPD patients, clusters exist based on phenotypic and biologic markers allowing for further understanding of endotypes. Recent studies suggest the role of eosinophils and optimal therapies for each condition may be different. Summary...
Source: Current Opinion in Allergy and Clinical Immunology - January 17, 2018 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Gustavo J. Rodrigo Source Type: research

Update on questionnaires for assessing adherence to inhaler devices in respiratory patients
The objective of this review was to update information on main questionnaires used in daily for assessing adherence to inhalers of patients with chronic respiratory diseases. Recent findings The test of the adherence to inhalers (TAI) is a recently developed and validated 12-item questionnaire to assess adherence to inhalers of aerosolized drugs in patients with asthma or COPD. The instrument can easily identify nonadherence, classify the level of adherence into good, intermediate and poor, and establish three nonadherence behaviour patterns of erratic, deliberate, and unwitting, which are useful for tailoring correctiv...
Source: Current Opinion in Allergy and Clinical Immunology - January 17, 2018 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Gustavo J. Rodrigo Source Type: research