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Cytokine-targeted therapies for asthma and COPD
This article reviews the mechanism of action and efficacy of the available biologics in asthma and COPD.
Source: European Respiratory Review - April 19, 2023 Category: Respiratory Medicine Authors: Schleich, F., Bougard, N., Moermans, C., Sabbe, M., Louis, R. Tags: COPD and smoking, Asthma and allergy Lung Science Conference reviews Source Type: research

Levels of immunoglobulin isotypes in serum and respiratory samples of patients with chronic obstructive pulmonary disease: protocol for a systematic review and meta-analysis
Introduction Chronic obstructive pulmonary disease (COPD) is an inflammatory respiratory disorder characterised by the progressive worsening of lung function. Acute exacerbation of COPD (AECOPD) is a leading contributor to patient morbidity, mortality and hospitalisations. The clinical significance of immunoglobulin (Ig) levels in COPD patients is not well established and is in need of further investigation. Methods and analysis We will conduct a systematic review to describe levels of different Ig isotypes (IgG, IgA and IgM) in various samples (serum, sputum and bronchoalveolar lavage) of patients with COPD. IgE levels i...
Source: BMJ Open - February 9, 2023 Category: General Medicine Authors: Unninayar, D., Shea, B., Cameron, D. W., Cowan, J. Tags: Open access, Immunology (including allergy) Source Type: research

Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Conclusions World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of eld...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research

A Bidirectional Label Propagation Based Computational Model for Potential Microbe-Disease Association Prediction
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research

Mepolizumab Beneficial in COPD With Eosinophilic Phenotype
Lower annual rate of moderate, severe exacerbations for patients receiving 100 mg mepolizumab
Source: Pulmonary Medicine News - Doctors Lounge - September 12, 2017 Category: Respiratory Medicine Tags: Internal Medicine, Allergy, Pharmacy, Pulmonology, Geriatrics, Conference News, Source Type: news

Bronchiectasthma and asthmectasis!
Respiratory disease can be considered as a species in constant evolution. Due to population growth and ageing only, and apart from the current 1.1 billion smokers, there have never been more respiratory patients ever in history than today [1]. With the latest World Health Organization (WHO) worldwide estimates of 400 million individuals with rhinitis, 334 million asthmatics, 328 million chronic obstructive pulmonary disease (COPD) patients and over 100 million with sleep apnoea, there is plenty of opportunity for the concurrence of two or more respiratory diseases in the same person. Not surprisingly, it is now commonplace...
Source: European Respiratory Journal - May 30, 2016 Category: Respiratory Medicine Authors: Soriano, J. B., Serrano, J. Tags: Asthma and allergy, CF and non-CF bronchiectasis Editorials Source Type: research

3rd Allergy, Asthma, & COPD Conference
25–26 January 2016, San Diego, United States
Source: Scientific and Medical Events on Global Events List - January 12, 2016 Category: Science Source Type: events

Air Quality and Climate Change: A Delicate Balance
Background image: © Elenamiv/Shutterstock John H. Tibbetts, based in Charleston, SC, is former editor of Coastal Heritage, the magazine of the South Carolina Sea Grant Consortium. About This Article open Citation: Tibbetts JH. 2015. Air quality and climate change: a delicate balance. Environ Health Perspect 123:A148–A153; http://dx.doi.org/10.1289/ehp.123-A148 News Topics: Air Pollution, Allergies, Asthma, Cardiovascular Health, Climate Change, Combustion Emissions, Dust, Natural Disasters, Ozone, Particulate Matter (PM), Pollen, Mold and Mycotoxins, Respiratory Health, Temperature, Weather Processes Published: 1 Jun...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Air Pollution Allergies Asthma Cardiovascular Health Climate Change Combustion Emissions Dust June 2015 Mold and Mycotoxins Natural Disasters Ozone Particulate Matter (PM) Pollen Respiratory Health Tem Source Type: research