• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Patterns of atopy and allergic-respiratory outcomes in older adults
Conclusions: Specific patterns of sensitization are differently associated with allergic respiratory outcomes in middle age. The poly-sensitization group appears to be at highest risk.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Bui, D., Lodge, C., Perret, J., Lowe, A., Abramson, M., Hamilton, G., Erbas, B., Walters, H., Dharmage, S. Tags: Allergy and immunology Source Type: research

The Human Upper Respiratory Tract Epithelium Is Susceptible to Flaviviruses
In this study, we exposed apically well-differentiated human NECs cultured at the ALI to the related flaviviruses ZIKV, JEV, WNV, and Usutu virus (USUV). We selected these viruses due to the recent increasing evidences of potential threat to humans (Cadar et al., 2017; Simonin et al., 2018). We show that NECs are particularly susceptible to JEV and WNV infection and to other flaviviruses included in this study. Infection with each virus led to shedding of infectious virus particles through the apical and basolateral surfaces and triggered host mechanisms at the level of inflammatory and antiviral mediators....
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury
In this study, we sought to further characterize ILC2s in the kidney, their location within this organ and determine their functional role in IRI using a loss-of-function approach. Here, we found that kidney ILC2s constitutively express IL-5 and are primarily located in close proximity to the renal vasculature, within the adventitia. Additionally, we demonstrate that a reduction, deficiency or depletion of ILC2s had minimal impact on the severity of IRI. Whilst activation of ILC2s and the associated amplification of local type 2 immunity has been previously shown to reduce the deleterious consequences of AKI, our results r...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Atopy in people aged 40  years and over: Relation to airflow limitation
Conclusion and Clinical RelevanceThe apparent association between atopy and post‐bronchodilator airflow limitation in the general population appears to be explained by the association between atopy and having ever diagnosed asthma and the effect of asthma on lung function.
Source: Clinical and Experimental Allergy - November 2, 2017 Category: Allergy & Immunology Authors: E. M. Guevara ‐Rattray, F. L. Garden, A. L. James, R. Wood‐Baker, M. J. Abramson, D. P. Johns, A. Sonia Buist, P. G. J. Burney, E. Haydn Walters, B. G. Toelle, G. B. Marks Tags: ORIGINAL ARTICLE Source Type: research

Atopy in people aged 40 and over: relation to airflow limitation
Conclusion and Clinical RelevanceThe apparent association between atopy and post‐bronchodilator airflow limitation in the general population appears to be explained by the association between atopy and having ever diagnosed asthma and the effect of asthma on lung function.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - October 1, 2017 Category: Allergy & Immunology Authors: Elyse Marie Guevara ‐Rattray, Frances L. Garden, Alan L. James, Richard Wood‐Baker, Michael J. Abramson, David P. Johns, A. Sonia Buist, Peter G.J. Burney, E. Haydn Walters, Brett G. Toelle, Guy B. Marks Tags: Original Article ‐Epidemiology of Allergic Disease Source Type: research

Occupational Pesticide and Herbicide Exposure Tied to Lung Disease Occupational Pesticide and Herbicide Exposure Tied to Lung Disease
Workers exposed to pesticides and herbicides on the job may be more likely than other people to develop chronic obstructive pulmonary disease (COPD), bronchitis and other breathing problems, an Australian study suggests.Reuters Health Information
Source: Medscape Allergy Headlines - August 1, 2017 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news