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Condition: Arthritis

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Total 2071 results found since Jan 2013.

Gene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells in Rheumatic Disorders: Ankylosing Spondylitis and Rheumatoid Arthritis.
Abstract No Abstract. PMID: 26996117 [PubMed - as supplied by publisher]
Source: Iranian Journal of Allergy, Asthma and Immunology - January 31, 2016 Category: Allergy & Immunology Authors: Almasi S, Aslani S, Poormoghim H, Jamshidi AR, Poursani S, Mahmoudi M Tags: Iran J Allergy Asthma Immunol Source Type: research

Soluble CD93 as a Novel Biomarker in Asthma Exacerbation.
In conclusion, the serum level of soluble CD93 is increased in patients with asthma exacerbation. It also showed that serum levels of sCD93 decreased with treatment of asthma attack. The clinical usefulness of determination of sCD93 as a biomarker of asthma requires further studies. PMID: 27334785 [PubMed]
Source: Allergy, Asthma and Immunology Research - June 24, 2016 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Onset of psoriatic arthritis associated with multiple wasp stings.
PMID: 27881293 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - November 19, 2016 Category: Allergy & Immunology Authors: Saco TV, Glaum MC, Ledford DK, Lockey RF Tags: Ann Allergy Asthma Immunol Source Type: research

Heat Shock Proteins: Therapeutic perspectives in inflammatory disorders.
Authors: Khandia R, Munjal AK, Iqbal HM, Dhama K Abstract Heat shock proteins (HSPs) are the highly conserved proteins present in all kingdoms of organisms. These are expressed under stress conditions in order to protect the cells from injuries. The stress induced protein denaturation is rectified by refolding and remodelling. These are intracellular proteins but can be present in extracellular fluid like serum of the patients suffering from trauma, autoimmune diseases and inflammatory disorders. Virtually in all the inflammatory diseases, immune response towards HSPs is developed. HSPs modulate the process of infl...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - December 18, 2016 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Hemophagocytic Lymphohistiocytosis mimics many common conditions: case series and review of literature.
Conclusion. Patients with HLH usually share various non-specific symptoms, such as fever and malaise, with patients across a wide spectrum of conditions: from bacterial sepsis to malignancies. Since early suspicion and diagnosis is critical to prompt therapy and improved mortality, including HLH as a possible cause of fever particularly in patients with prolonged fever of unknown origin and cytopenias will be crucial. PMID: 28120605 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - January 27, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Monogenic Auto-in flammatory Syndromes: A Review of the Literature.
Monogenic Auto-inflammatory Syndromes: A Review of the Literature. Iran J Allergy Asthma Immunol. 2016 Dec;15(6):430-444 Authors: Azizi G, Khadem Azarian S, Nazeri S, Mosayebian A, Ghiasy S, Sadri G, Mohebi A, Khan Nazer NH, Afraei S, Mirshafiey A Abstract Auto-inflammatory syndromes are a new group of distinct hereditable disorders characterized by episodes of seemingly unprovoked inflammation (most commonly in skin, joints, gut, and eye), the absence of a high titer of auto-antibodies or auto-reactive T cells, and an inborn error of innate immunity. A narrative literature review was carried out of ...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 30, 2016 Category: Allergy & Immunology Authors: Azizi G, Khadem Azarian S, Nazeri S, Mosayebian A, Ghiasy S, Sadri G, Mohebi A, Khan Nazer NH, Afraei S, Mirshafiey A Tags: Iran J Allergy Asthma Immunol Source Type: research

Silymarin (Livergol ®) Decreases Disease Activity Score in Patients with Rheumatoid Arthritis: A Non-randomized Single-arm Clinical Trial.
Silymarin (Livergol®) Decreases Disease Activity Score in Patients with Rheumatoid Arthritis: A Non-randomized Single-arm Clinical Trial. Iran J Allergy Asthma Immunol. 2017 Apr;16(2):99-106 Authors: Shavandi M, Moini A, Shakiba Y, Mashkorinia A, Dehghani M, Asar S, Kiani A Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease, which can lead to joint destruction and disability. Pannus formation due to chronic synovitis is the hallmark of RA. Oxidative stress as a consequence of immune cell activation and disease-modifying anti-rheumatic drugs can prevent inflammation and tissue destruct...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2017 Category: Allergy & Immunology Authors: Shavandi M, Moini A, Shakiba Y, Mashkorinia A, Dehghani M, Asar S, Kiani A Tags: Iran J Allergy Asthma Immunol Source Type: research

Hematological Improvement of Patients with Active Rheumatoid Arthritis by β-D-Mannuronic Acid (M2000) as a Novel NSAID with Immunosuppressive Property.
This study was conducted on 25 patients with active rheumatoid arthritis (RA) (identifier: IRCT2014011213739N2). M2000 was administered orally for anemic and non-anemic RA patients at a dose of 500 mg twice daily for 12 weeks. The patients were permitted to continue the conventional treatments excluding NSAIDs. Blood samples were collected at baseline, 4 and 12 weeks after drug administration and were tested for hematological parameters. Moreover, serum levels of TNF-α and IL-6 were analysed before and after M2000 therapy compared to healthy controls using enzyme linked immunosorbent assay method. We found a significant i...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 1, 2017 Category: Allergy & Immunology Authors: Ahmadi H, Jamshidi AR, Mahmoudi M, Gharibdoost F, Vojdanian M, Fattahi MJ, Rastkari N, Aghazadeh Z, Mirshafiey A Tags: Iran J Allergy Asthma Immunol Source Type: research

Th1-Th17 Ratio as a New Insight in Rheumatoid Arthritis Disease.
Abstract The Th17, Th1 and dual Th17/Th1 cells are important players in rheumatoid arthritis (RA) disease. To assess their roles, the frequency and impact of these cells were investigated in patients with different disease activity. In 14 new cases and 41 established RA patients in comparison with 22 healthy controls, the percentages of Th17, Th1 and dual Th17/Th1 cells were determined by flow-cytometry and their correlations were investigated with disease activity score (DAS28). Moreover, serum levels of IL-6 and IL-17 as inducer and functional cytokines for Th17 were investigated. Finally, serum levels of anti c...
Source: Iranian Journal of Allergy, Asthma and Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Bazzazi H, Aghaei M, Memarian A, Asgarian-Omran H, Behnampour N, Yazdani Y Tags: Iran J Allergy Asthma Immunol Source Type: research

Anti-Arthritic Effect of Garcinol Enriched Fraction Against Adjuvant Induced Arthritis.
CONCLUSION: Garcinol enriched fraction shows anti-arthritic activity in experimental animals. PMID: 30457056 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - November 22, 2018 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Immunomodulatory Effects of Human Adipose Tissue-derived Mesenchymal Stem Cells on T Cell Subsets in Patients with Rheumatoid Arthritis.
This study was designed to investigate the effects of co-cultured Ad-MSCs on peripheral blood mononuclear cells (PBMCs) of RA patients and healthy individuals, through assessing transcription factors of T cell subsets. PBMCs from RA patients and healthy donors were co-cultured with Ad-MSCs with or without Phytohaemagglutinin (PHA). The quantitative real-time polymerase chain reaction (qRT-PCR) was used to measure the expression of T-box 21 (T-bet), GATA-binding protein-3 (GATA3), retinoid-related orphan receptor γt (ROR-γt) and forkhead box P3 (Foxp3). Based on the results, Ad-MSCs greatly upregulated Th2 and Treg cell...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 31, 2019 Category: Allergy & Immunology Authors: Baharlou R, Rashidi N, Ahmadi-Vasmehjani A, Khoubyari M, Sheikh M, Erfanian S Tags: Iran J Allergy Asthma Immunol Source Type: research

The First Case Series of Cryopyrin-Associated Periodic Syndrome in Korea.
Authors: Han JH, Je YJ, Yoon HJ, Ahn JG, Lee JS, Park JW, Park HJ Abstract Cryopyrin-associated periodic syndrome (CAPS) is a hereditary autoinflammatory syndrome caused by mutations in NLRP3 (encoding cryopyrin), which presents with fever, fatigue and arthralgia. Thus far, however there have been no reports of CAPS in Korea. Herein, we report 3 cases of CAPS for the first time in Korea. The first case, a 28-year-old man with recurrent urticaria, arthralgia and fever induced by cold, all of which were observed in his father, showed elevated erythrocyte sedimentation rate and C-reactive protein. He exhibited a p.Gly...
Source: Allergy, Asthma and Immunology Research - June 8, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Lupus Erythematosus and Chronic Granulomatous Disease: Report of Four Iranian Patients with AR-CGD and One XL-CGD.
Abstract Chronic granulomatous disease (CGD) is a rare genetic disorder of neutrophil activity, resulting in increased rate of recurrent infections with catalase-positive bacteria and fungi, as well as various autoimmune diseases such as sarcoidosis, rheumatoid arthritis, and discoid and/or systemic lupus erythematosus. Few reports have reported lupus erythematosus (LE) in patients with X-linked CGD (XL-CGD) and carriers, and very few in autosomal recessive CGD (AR-CGD). Here, we present 5 patients with CGD developing LE at different ages to emphasize on the importance of appropriate follow-up and treatment in pat...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 16, 2019 Category: Allergy & Immunology Authors: Maddah M, Fazlollahi MR, Shiari R, Shahram F, Mamishi S, Babaie D, Monajemzadeh M, Sotudeh S, Hamidieh AA, Badalzadeh M, Tajik S, Sedighipour L, Pourpak Z Tags: Iran J Allergy Asthma Immunol Source Type: research

The Situation of Chemokine Ligands and Receptors Gene Expression, Following the Oral Administration of Drug Mannuronic Acid in Rheumatoid Arthritis Patients.
CONCLUSION: Taken together, the results of this investigation revealed the part of molecular and immunological mechanisms of drug Mannuronic acid (M2000) in treatment of RA, based on chemokine ligands and receptors mediated processes. PMID: 31729947 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - November 16, 2019 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Adverse effects of TNF inhibitor in a patient with DiGeorge syndrome and juvenile idiopathic arthritis.
PMID: 31734327 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - November 13, 2019 Category: Allergy & Immunology Authors: Sestan M, Kifer N, Frkovic M, Laskarin AM, Jelusic M Tags: Ann Allergy Asthma Immunol Source Type: research