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Specialty: Cardiology
Condition: Cardiomyopathy
Education: Study
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Total 256 results found since Jan 2013.
Multipoint left ventricular pacing effects on hemodynamic parameters and functional status: HUMVEE single-arm clinical trial (NCT03189368)
CONCLUSIONS: optimized MPP showed significant improvements on hemodynamic parameters and ventricular function, in heart failure patients over optimized CRT. The beneficial effect was more prominent in men and in those with rather reduced LVEF, consistent with findings suggesting a beneficial trend in VAC and CP with the more homogenous depolarization offered by optimized MPP.PMID:33677032 | DOI:10.1016/j.hjc.2021.02.012
Source: Hellenic Journal of Cardiology - March 7, 2021 Category: Cardiology Authors: Christos-Konstantinos Antoniou Polychronis Dilaveris Christina Chrysohoou Konstantinos Konstantinou Nikolaos Magkas Panagiotis Xydis Panagiota Manolakou Ioannis Skiadas Konstantinos A Gatzoulis Dimitris Tousoulis Costas Tsioufis Source Type: research
One ‐year results of the first‐in‐man study investigating the Atrial Flow Regulator for left atrial shunting in symptomatic heart failure patients: the PRELIEVE study
ConclusionsImplantation of the AFR device in HF patients was feasible. No shunt occlusion, stroke or new right HF was observed during the 1 ‐year follow‐up, with clinical improvements in certain patients.
Source: European Journal of Heart Failure - March 6, 2021 Category: Cardiology Authors: Christina Paitazoglou,
Martin W. Bergmann,
Ramazan Özdemir,
Roman Pfister,
Jozef Bartunek,
Teoman Kilic,
Alexander Lauten,
Alexander Schmeisser,
Mehdi Zoghi,
Stefan D. Anker,
Horst Sievert,
Felix Mahfoud,
AFR‐PRELIEVE Investigators Tags: Research Article Source Type: research
A critical approach for successful use of circulating microRNAs as biomarkers in cardiovascular diseases: the case of hypertrophic cardiomyopathy
AbstractMicroRNAs (miRNAs) are small noncoding RNA molecules that act as major regulators of gene expression at the post-transcriptional level. As the potential applications of miRNAs in the diagnosis and treatment of human diseases have become more evident, many studies of hypertrophic cardiomyopathy (HCM) have focused on the systemic identification and quantification of miRNAs in biofluids and myocardial tissues. HCM is a hereditary cardiomyopathy caused by mutations in genes encoding proteins of the sarcomere. Despite overall improvements in survival, progression to heart failure, stroke, and sudden cardiac death remain...
Source: Heart Failure Reviews - March 3, 2021 Category: Cardiology Source Type: research
The prevalence, predictors, and outcomes of spontaneous echocardiographic contrast or left ventricular thrombus in patients with HFrEF
ConclusionsIn patients with HFrEF, SEC was not uncommon and increased risk of ischaemic stroke as well as LVT. Anticoagulants could play a role in the reduction of stroke risk, suggesting that patients with SEC/LVT, even those in sinus rhythm, would benefit from systemic anticoagulation treatment.
Source: ESC Heart Failure - January 26, 2021 Category: Cardiology Authors: Xiaodong Zhou,
Ruiyu Shi,
Gaojun Wu,
Qianli Zhu,
Changzuan Zhou,
Liangguo Wang,
Chenglong Xue,
Yuanyuan Jiang,
Xueli Cai,
Weijian Huang,
Peiren Shan Tags: Original Research Article Source Type: research
Cardiovascular Complications of Prostate Cancer Therapy
AbstractPurpose of reviewWith treatment advances, the most common cause of death in prostate cancer patients is cardiovascular disease. Discerning the contribution of prostate cancer treatment on cardiovascular complications versus the natural progression of cardiovascular disease remains an ongoing area of investigation. Evaluating the research and identifying opportunities for further investigation is critical for optimal care of this prostate cancer patient population.Recent findingsThe degree that hormone therapy contributes to cardiovascular morbidity and mortality remains uncertain with conflicting results from large...
Source: Current Treatment Options in Cardiovascular Medicine - November 12, 2020 Category: Cardiology Source Type: research
EvaLuation Using Cardiac Insertable Devices And TelephonE in Hypertrophic Cardiomyopathy (ELUCIDATE HCM): A prospective observational study on incidence of arrhythmias
ConclusionIn this first prospective study using an ICM, the arrhythmia burden in HCM patients yielded 30.0% AF and 23.3% NSVT.
Source: Journal of Cardiovascular Electrophysiology - November 4, 2020 Category: Cardiology Authors: Peter Magnusson,
Stellan M örner Tags: ORIGINAL ‐ DEVICES Source Type: research
EvaLuation Using Cardiac Insertable Devices And TelephonE in Hypertrophic Cardiomyopathy (ELUCIDATE HCM): a prospective observational study on incidence of arrhythmias
ConclusionIn this first prospective study using an ICM, the arrhythmia burden in HCM patients yielded 30.0% AF and 23.3% NSVT.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - October 27, 2020 Category: Cardiology Authors: Peter Magnusson,
Stellan M örner Tags: ORIGINAL ‐ DEVICES Source Type: research
Anticoagulation for Stroke Prevention in Patients With Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review
Atrial fibrillation is the most common arrhythmia in patients with hypertrophic cardiomyopathy with a prevalence and incidence of 23% and 3.1% respectively. The risk of thromboembolism is high in patients with hypertrophic cardiomyopathy regardless of the CHADS2VASC score. This review includes five observational studies that focused on prevention of thromboembolism in patients with hypertrophic cardiomyopathy and atrial fibrillation. These papers evaluated and compared outcomes between patients on either warfarin or direct oral anticoagulants.
Source: Heart Rhythm - October 2, 2020 Category: Cardiology Authors: M. Farhan Nasser, Sanjay Gandhi, Robert J. Siegel, Florian Rader Source Type: research
Atrial fibrillation, anticoagulation management and risk of stroke in the Cardiomyopathy/Myocarditis registry of the EURObservational Research Programme of the European Society of Cardiology
ConclusionsThe study reveals a high prevalence and diverse distribution of AF in patients with cardiomyopathies, inadequate anticoagulation regimen, and high risk of stroke/TIA in this population.
Source: ESC Heart Failure - September 16, 2020 Category: Cardiology Authors: Katarzyna Mizia ‐Stec,
Alida L.P. Caforio,
Philippe Charron,
Juan R. Gimeno,
Perry Elliott,
Juan Pablo Kaski,
Aldo P. Maggioni,
Luigi Tavazzi,
Angelos G. Rigopoulos,
Cecile Laroche,
Attila Frigy,
Elisabetta Zachara,
Maria Luisa Pena‐Pena, Tags: Original Research Article Source Type: research
Mortality risk in dilated cardiomyopathy: the accuracy of heart failure prognostic models and dilated cardiomyopathy ‐tailored prognostic model
ConclusionsAn analysis of various HF prognostic models found them to be suboptimal for DCM patients. A self ‐developed DCM prognostic model showed improved performance over the nine other models studied. However, further validation of the prognostic model in different DCM populations is required.
Source: ESC Heart Failure - August 26, 2020 Category: Cardiology Authors: Ewa Dziewi ęcka,
Matylda Gliniak,
Mateusz Winiarczyk,
Arman Karapetyan,
Sylwia Wiśniowska‐Śmiałek,
Aleksandra Karabinowska,
Marcin Dziewięcki,
Piotr Podolec,
Paweł Rubiś Tags: Original Research Article Source Type: research
Cardiac complications in inherited mitochondrial diseases
In this study, we looked at molecular genetics of MIDs and cardiac manifestations in patients with mitochondrial dysfunction.
Source: Heart Failure Reviews - July 28, 2020 Category: Cardiology Source Type: research
Current Treatment Options in Cardiovascular Medicine: Update on Reversible Cerebral Vasoconstriction Syndrome
ConclusionRCVS can now be accurately diagnosed using clinical and imaging features available upon presentation. Advances in knowledge about the risk factors, prognosis, and potential harmful effects of certain therapeutic strategies, are expected to optimize the management of this increasingly well recognized syndrome.
Source: Current Treatment Options in Cardiovascular Medicine - July 13, 2020 Category: Cardiology Source Type: research
Biventricular imaging markers to predict outcomes in non ‐compaction cardiomyopathy: a machine learning study
ConclusionsOur findings show the importance of biventricular assessment to detect the severity of this cardiomyopathy and to plan for early clinical intervention. In addition, this study shows that even patients with normal LV function and negative late gadolinium enhancement had MACE. ML is a promising tool for analysing a large set of parameters to stratify and predict prognosis in LVNC patients.
Source: ESC Heart Failure - June 29, 2020 Category: Cardiology Authors: Camila Rocon,
Mahdi Tabassian,
Marcelo Dantas Tavares de Melo,
Jose Arimateia Araujo Filho,
Cesar Jos é Grupi,
Jose Rodrigues Parga Filho,
Edimar Alcides Bocchi,
Jan D'hooge,
Vera Maria Cury Salemi Tags: Original Research Article Source Type: research
Direct oral anticoagulants compared to vitamin K antagonist for the management of left ventricular thrombus
ConclusionsOur data suggest that DOACs are likely to be at least as effective and safe as VKA for stroke prevention in patients with LV thrombus and, despite their lack of a licence for this indication, are therefore likely to represent a reasonable and more convenient option for this setting. The optimal timing and type of anticoagulation for LV thrombus, as well as the role of screening for high ‐risk patients, should be tested in prospective, randomized trials.
Source: ESC Heart Failure - June 24, 2020 Category: Cardiology Authors: Hansa Iqbal,
Sam Straw,
Thomas P. Craven,
Katherine Stirling,
Stephen B. Wheatcroft,
Klaus K. Witte Tags: Original Research Article Source Type: research
