• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Aspirin Desensitization in NERD in the Era of Biologics: First or Last Resource?
AbstractPurpose of the ReviewThe classic treatment of non-steroidal anti-inflammatory drug (NSAID) exacerbated respiratory disease (NERD) includes aspirin desensitization (AD). Introduction of biologics in the treatment of asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) has raised the question: which of the two options may be the most suitable for NERD?Recent FindingsNERD is a highly eosinophilic disease. Monoclonal antibodies targeting IL-5 or the IL-5 receptor, involved in eosinophil recruitment, have been shown to be effective in asthma and CRSwNP. However, no difference in clinical efficacy was observed be...
Source: Current Treatment Options in Allergy - March 9, 2022 Category: Allergy & Immunology Source Type: research

Influence of omalizumab on treatment costs for chronic rhinosinusitis with nasal polyps and asthma: an insurance claims analysis
Source: International Forum of Allergy and Rhinology - October 1, 2021 Category: Allergy & Immunology Authors: Lauren T. Roland, Sarah K. Wise, Heqiong Wang, Christina Mehta, John M. DelGaudio, Joshua M. Levy Tags: RESEARCH NOTE Source Type: research

Longitudinal progression of aspirin ‐exacerbated respiratory disease: analysis of a national insurance claims database
ConclusionUpper and lower airway disease is often initially recognized in patients with AERD, whereas drug sensitivity presents month to years later. This delay may be due to the pathophysiology of AERD and disease progression or due to practice patterns in diagnostic testing and coding. Further work is warranted to identify these patients at early stages in their disease progression.
Source: International Forum of Allergy and Rhinology - August 22, 2019 Category: Allergy & Immunology Authors: Lauren T. Roland, Heqiong Wang, C. Christina Mehta, Katherine N. Cahill, Tanya M. Laidlaw, John M. DelGaudio, Sarah K. Wise, Joshua M. Levy Tags: ORIGINAL ARTICLE Source Type: research

Association between chronic rhinosinusitis and osteoporosis: a case ‐control study using a national sample cohort
ConclusionThe ORs of CRS were increased in osteoporosis participants. This relation was consistent in all age and sex groups.
Source: International Forum of Allergy and Rhinology - June 16, 2019 Category: Allergy & Immunology Authors: Hyo Geun Choi, Gyu Kong Tags: ORIGINAL ARTICLE Source Type: research

How often is sinus surgery performed for chronic rhinosinusitis with versus without nasal polyps?
CONCLUSION: Almost 30% of ESS were performed for CRSwNP, and these cases were, on average, more extensive, used more OR time, and more often used image guidance than surgeries for CRSsNP. The rate of surgery performed for CRSwNP varied based on geography, payer, and surgical volume, which indicted that patient selection impacted surgical management. PMID: 29336288 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2018 Category: ENT & OMF Authors: Ference EH, Suh JD, Tan BK, Smith SS Tags: Am J Rhinol Allergy Source Type: research

Revision rates and time to revision following endoscopic sinus surgery: A large database analysis
ConclusionsA minority of patients with CRS who undergo ESS will have a revision surgery. This likelihood is increased in female patients and those with nasal polyps, and decreased in patients of Hispanic ethnicity, even when controlling for income, insurance, and hospital setting. Level of Evidence4. Laryngoscope, 2017
Source: The Laryngoscope - July 8, 2017 Category: ENT & OMF Authors: Nathan R. Stein, Aria Jafari, Adam S. DeConde Tags: Allergy/Rhinology Source Type: research

Associations between Unconventional Natural Gas Development and Nasal and Sinus, Migraine Headache, and Fatigue Symptoms in Pennsylvania
Conclusions: This study provides evidence that UNGD is associated with nasal and sinus, migraine headache, and fatigue symptoms in a general population representative sample. Citation: Tustin AW, Hirsch AG, Rasmussen SG, Casey JA, Bandeen-Roche K, Schwartz BS. 2017. Associations between unconventional natural gas development and nasal and sinus, migraine headache, and fatigue symptoms in Pennsylvania. Environ Health Perspect 125:189–197; http://dx.doi.org/10.1289/EHP281 Address correspondence to B.S. Schwartz, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., Room W7041, Baltimore, MD 21205 USA. Teleph...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Asthma associated with chronic rhinosinusitis: a population ‐based study
ConclusionAsthma was associated with increased risks of CRSwNP and CRSsNP, independent of several potential confounding factors.
Source: International Forum of Allergy and Rhinology - June 28, 2016 Category: Allergy & Immunology Authors: Yu ‐Ting Chen, Chen‐Yu Chien, Shu‐Yu Tai, Chiu‐Mieh Huang, Charles Tzu‐Chi Lee Tags: ORIGINAL ARTICLE Source Type: research

Asthma associated with chronic rhinosinusitis: a population‐based study
ConclusionAsthma was associated with increased risks of CRSwNP and CRSsNP, independent of several potential confounding factors.
Source: International Forum of Allergy and Rhinology - May 31, 2016 Category: Allergy & Immunology Authors: Yu‐Ting Chen, Chen‐Yu Chien, Shu‐Yu Tai, Chiu‐Mieh Huang, Charles Tzu‐Chi Lee Tags: ORIGINAL ARTICLE Source Type: research

Chronic obstructive pulmonary disease predicts chronic rhinosinusitis without nasal polyps: A population-based study.
CONCLUSION: COPD was associated with an increased risk of CRSsNP in this study population, independent of a number of potential confounding factors. PMID: 25975242 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2015 Category: ENT & OMF Authors: Chien CY, Tai SY, Wang LF, Lee CT Tags: Am J Rhinol Allergy Source Type: research