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Cancer: Prostate Cancer
Procedure: PET Scan

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Total 2579 results found since Jan 2013.

The prognostic significance of a negative PSMA-PET scan prior to salvage radiotherapy following radical prostatectomy
CONCLUSION: Favorable bRFS after SRT in patients with BR and negative PSMA-PET following RP was achieved. These data support the usage of early SRT for patients with negative PSMA-PET findings.PMID:37736808 | DOI:10.1007/s00259-023-06438-3
Source: Molecular Medicine - September 22, 2023 Category: Molecular Biology Authors: Sonja Adebahr Alexander Althaus Sophia Scharl Iosif Strouthos Andrea Farolfi Francesca Serani Helena Lanzafame Christian Trapp Stefan A Koerber Jan C Peeken Marco M E Vogel Alexis Vrachimis Simon K B Spohn Anca-Ligia Grosu Stephanie G C Kroeze Matthias Gu Source Type: research

A Case of Metastatic Papillary Thyroid Carcinoma in Neck Lymph Nodes Without Primary Tumor in Thyroid Gland
We report the case of a 63-year-old male who had a left neck level II palpable mass. A left cervical mass had previously undergone 2 central needle biopsies, but only atypical cells had been identified. His prior medical history included surgical treatment for prostate cancer 11 years ago. There was no suspicious primary tumor in the endoscopic examination. After the excisional biopsy, the pathologic finding was metastatic papillary carcinoma from the thyroid, and there were no aberrant findings in the thyroid sonography. The patient underwent a complete thyroidectomy, bilateral central neck dissection (CND), and left leve...
Source: Ear, Nose and Throat Journal - September 15, 2023 Category: ENT & OMF Authors: Sung Ha Jung Joo Hyun Park Junyoung Kim Nayeon Choi Source Type: research

Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer
Urologie. 2023 Sep 13. doi: 10.1007/s00120-023-02189-z. Online ahead of print.ABSTRACTProstate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens up new diagnostic opportunities. PSMA-PET/CT (PET: positron-emission tomography) is already well established in high-risk PCa for primary staging and tumor localization when biochemical recurrence occurs. Further potential indications for PSMA-...
Source: Nuklearmedizin - September 13, 2023 Category: Radiology Authors: Anna-Sophie Strau ß Christian Bolenz Ambros J Beer Friedemann Zengerling Meinrad Beer Jonathan Miksch Source Type: research

18F-prostate specific membrane antigen positron emission tomography/computerized tomography for lymph node staging in medium/high risk prostate cancer: A systematic review and meta-analysis
CONCLUSIONS: 18F-PSMA PET/CT showed moderate sensitivity but high specificity in lymph node staging of medium/high-risk PCa. The diagnostic efficacy was almost equivalent to that reported for 68Ga-PSMA PET/CT.REGISTRATION: International Prospective Register of Systematic Reviews (PROSPERO), No. CRD42023391101.PMID:37690993 | DOI:10.1097/CM9.0000000000002850
Source: Chinese Medical Journal - September 10, 2023 Category: General Medicine Authors: Zhengtong Lv Liuqi Song Miao Wang Huimin Hou Haodong Li Xuan Wang Jianye Wang Jianlong Wang Ming Liu Source Type: research

Cancers, Vol. 15, Pages 4404: PET/CT and Conventional Imaging for the Assessment of Neuroendocrine Prostate Cancer: A Systematic Review
Conclusion: Published data on the role of PET/CT for the assessment of NEPC are limited. At present, it is still uncertain which tracer performs best, and although [18F]FDG has been evaluated and seems to offer some advantages in availability and clinical staging, other tracers may be more useful to understand tumor biology or identify targets for subsequent radioligand therapy. Further research is therefore desirable. In contrast, data are still limited to draw a final conclusion on the role and the specific characteristics of CI in this rare form of neoplasm, and therefore, more studies are needed in this setting.
Source: Cancers - September 3, 2023 Category: Cancer & Oncology Authors: Francesco Dondi Alessandro Antonelli Nazareno Suardi Andrea Emanuele Guerini Domenico Albano Silvia Lucchini Luca Camoni Giorgio Treglia Francesco Bertagna Tags: Review Source Type: research

PSMA PET/CT and PET/MRI in primary staging of prostate cancer and its effect on patient management
ConclusionsDespite the clear superiority of PSMA PET over conventional imaging for primary staging of intermediate- and high-risk PCa, PSMA PET is currently not yet identified as the gold standard imaging modality in this setting in the European Association of Urology (EAU) guidelines, given that no prospective studies demonstrating a clear benefit of treatment adaptation are available at this moment. The results of prospective trials exploring the benefit of PSMA PET-based treatment algorithms are, therefore, strongly awaited.
Source: Clinical and Translational Imaging - August 30, 2023 Category: Radiology Source Type: research

Prostate-specific membrane antigen-based imaging for stereotactic irradiation of low-volume progressive prostate cancer: a single-center experience
CONCLUSION: PSMA-based imaging is a promising diagnostic method for specifying the stage and detecting the low-volume progression. Our results suggest that PSMA-based hybrid imaging can influence treatment decisions and target volume delineation for SBRT.PMID:37637070 | PMC:PMC10448522 | DOI:10.3389/fonc.2023.1166665
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Linda Varga Zsuzsanna Besenyi Viktor R Paczona Istv án Farkas Szabolcs Urb án G ábor Sipka L ászló Pávics Zoltan Varga Emese Fodor Katalin Hidegh éty Judit Olah Zolt án Bajory Anik ó Maráz Source Type: research

A randomised trial of < sup > 18 < /sup > FPSMA-1007-PET/CT versus NaF-PET/CT for staging primary prostate cancer: A trial protocol
BJUI Compass. 2023 May 12;4(5):513-522. doi: 10.1002/bco2.243. eCollection 2023 Sep.ABSTRACTBACKGROUND: Prostate-specific membrane antigen (PSMA)-positron emission tomography/contrast-enhanced computed tomography (PET/CT) is a sensitive imaging modality for prostate cancer (PCa). Due to lack of knowledge of the patient benefit, PSMA-PET/CT is not yet recommended in the European guidelines for staging and treatment planning of patients with newly diagnosed PCa. We will investigate the potential difference in progression-free survival (PFS) and quality of life (QoL) of using PSMA-PET/CT versus sodium fluoride (NaF)-PET/CT fo...
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Karen Middelbo Buch-Olsen Mads Hvid Poulsen Steinbj ørn Hansen Mie Holm Vilstrup Jorun Holm S øren Hess Paw Christian Holdgaard Karsten Egbert Arnold Zieger S øren Sørensen Madsen Oke Gerke Kasper Tholstrup Pedersen Johan Hygum Dam Niels Langkj ær Lo Source Type: research

The diagnostic accuracy of radiolabeled PSMA-ligand PET for tumour staging in newly diagnosed prostate cancer patients compared to histopathology: a systematic review and meta-analysis
CONCLUSION: The present investigation has demonstrated that PSMA PET/MRI surpasses currently recommended multiparametric magnetic resonance imaging (mpMRI) in terms of diagnostic accuracy as inferred from a notable data trajectory, whereas PSMA-PET/CT exhibited comparable diagnostic accuracy for intraprostatic tumour detection and T-staging compared to mpMRI. Nevertheless, the analysis has identified certain potential limitations, such as small-study effects and a potential for publication bias, which may impact the overall conclusions drawn from this study.PMID:37597010 | DOI:10.1007/s00259-023-06392-0
Source: Molecular Medicine - August 19, 2023 Category: Molecular Biology Authors: Farid Gossili Anna Winther Mogensen Tea Caroline Konnerup Kirsten Bouchelouche Ian Alberts Ali Afshar-Oromieh Helle D Zacho Source Type: research