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Total 197 results found since Jan 2013.
Risk stratification of invasive cervical cancer diagnosed after cervical conization
CONCLUSION: HPV16 positivity and nulliparity were identified as risk factors for undetected ICC. Careful treatment selection and preoperative scrupulous examination are especially important in these cases.PMID:37681246 | DOI:10.1093/jjco/hyad121
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Tomoka Shiga Ayumi Taguchi Mayuyo Mori Shogo Yamaguchi Harunori Honjoh Akira Nishijima Satoko Eguchi Yuichiro Miyamoto Kenbun Sone Kei Kawana Yutaka Osuga Source Type: research
Prevalence of human papillomavirus infection in abnormal pap smears
CONCLUSION: Our study shows that the percentage of HR-HPV-positive case increases with the severity of cytologic morphology. HPV had 4 times higher positivity in squamous intraepithelial lesion as compared to ASCUS.PMID:37681080 | PMC:PMC10481853 | DOI:10.25259/Cytojournal_8_2021
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Jaya Mishra Sweety Kalantri Vandana Raphael Biswajit Dey Yookarin Khonglah Ananya Das Source Type: research
The involvement of MALAT1-ALKBH5 signaling axis into proliferation and metastasis of human papillomavirus-positive cervical cancer
Cancer Biol Ther. 2023 Dec 31;24(1):2249174. doi: 10.1080/15384047.2023.2249174.ABSTRACTInfection with high-risk human papillomavirus (HPV), for example, with types 16 and 18, is closely associated with cervical cancer development, which continues to threaten women's health globally. Although HPV oncogenes have been recognized as the main cause of transformation of normal cervical epithelial cells, non-coding RNA could also be involved in the initiation and promotion of cervical cancer development. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a well-documented long non-coding RNA (lncRNA), has been prev...
Source: Cancer Biology and Therapy - August 28, 2023 Category: Cancer & Oncology Authors: Suzhen Wu Lili Liu Huanying Xu Qiaoling Zhu Minhua Tan Source Type: research
Assessment of Human Papillomavirus Non-16/18, Type-Specific Risk for Cervical Intraepithelial Neoplasia Grade 3 or Worse Among Women With Cervical Atypical Glandular Cells
CONCLUSION: Among non-16/18 HPV types in AGC, HPV31 and 33 had the highest risk for CIN 3 or worse, whereas most of the women with invasive cancer were positive for HPV45. Extended HPV genotyping may be helpful for the management of AGC.PMID:37535949 | DOI:10.1097/AOG.0000000000005286
Source: Obstetrics and Gynecology - August 3, 2023 Category: OBGYN Authors: Emel Yilmaz Camilla Lagheden Mehran Ghaderi Jiangrong Wang Joakim Dillner K Miriam Elfstr öm Source Type: research
Cervical cancer: a tale from HPV infection to PARP inhibitors
Genes Dis. 2022 Nov 10;10(4):1445-1456. doi: 10.1016/j.gendis.2022.09.014. eCollection 2023 Jul.ABSTRACTGlobally, cervical cancer (CxCa) ranks 4th common cancer among females and led to 569,847 incidences and 311,365 deaths in 2018. 80% of CxCa cases occur due to persistent infection with a high-risk subtype of human papillomavirus (HPV-16 and 18). Smoking, high parity, and co-infection with type 2 herpes simplex or HIV are other known risk factors for CxCa. Major histological subtypes are squamous (70%) and adenocarcinoma (25%). Presently, concurrent radiation plus cisplatin (CDDP)-based chemotherapy is the standard treat...
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Minakshi Mann Vikram Pratap Singh Lalit Kumar Source Type: research
The combined finding of HPV 16, 18, or 45 and cytologic Atypical Glandular Cells (AGC) indicates a greatly elevated risk of in situ and invasive cervical adenocarcinoma
CONCLUSION: Detection of HPV 16/18/45 positivity elevates risk of adenocarcinoma, particularly if AGC cytology is also found.PMID:37243996 | DOI:10.1016/j.ygyno.2023.05.011
Source: Gynecologic Oncology - May 27, 2023 Category: Cancer & Oncology Authors: Mark Schiffman Lisa Mirabello Didem Egemen Brian Befano Yanzi Xiao Nicolas Wentzensen Tina Raine-Bennett Ritu Nayar Li C Cheung Anne Rositch Terri Beaty Rebecca B Perkins Silvia de Sanjose Thomas Lorey Philip E Castle Robert D Burk Source Type: research
Infection with human cytomegalovirus, Epstein-Barr virus, and high-risk types 16 and 18 of human papillomavirus in EGFR-mutated lung adenocarcinoma
CONCLUSION: HCMV, EBV, and high-risk HPV infections are more frequent in EGFR-mutated lung adenocarcinomas, which indicates a possible viral impact on the etiology of this lung cancer subtype.PMID:37131310
Source: Croatian Medical Journal - May 3, 2023 Category: General Medicine Authors: Suzana Harabajsa Hajdi Šefčić Marija Klasi ć Marija Milavi ć Snje žana Židovec Lepej Ivana Grgi ć Matea Zajc Petranovi ć Marko Jakopovi ć Silvana Smojver-Je žek Petra Kora ć Source Type: research
