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Cancer: Squamous Cell Carcinoma
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Total 130 results found since Jan 2013.
Encephalitis in a patient with hypopharynx cancer treated with immune checkpoint inhibitors and radiotherapy: a case report and review of the literature
J Cancer Res Clin Oncol. 2023 Sep 7. doi: 10.1007/s00432-023-05328-3. Online ahead of print.ABSTRACTHypopharyngeal cancer (HPC) has one of the most unfavorable prognoses among head and neck squamous cell carcinomas. Immunotherapy in combination with chemotherapy, the same as conventional induction chemotherapy, has emerged as a vital part of the induction therapy protocol for HPC. Meanwhile, the incidence of immune-related adverse events is increasing. In this light, we present the first reported case of immune-associated encephalitis in a patient with hypopharyngeal cancer treated with Camrelizumab (a PD-1 inhibitor). Aft...
Source: Cell Research - September 7, 2023 Category: Cytology Authors: Yan Kang Hongchao Zhen Nina Ma Hong Zhao Bangwei Cao Source Type: research
Diffusion-weighted imaging in the assessment of cervical cancer: comparison of reduced field-of-view diffusion-weighted imaging and conventional techniques
CONCLUSION: Compared with f-FOV DWI, r-FOV DWI might provide clearer imaging, fewer artifacts, less distortion, and higher image quality for the diagnosis of CC and might assist in the detection of CC.PMID:37545177 | DOI:10.1177/02841851231183870
Source: Acta Radiologica - August 7, 2023 Category: Radiology Authors: Yakun He Min Wang Siqi Yi Yujie Lu Jing Ren Peng Zhou Ke Xu Source Type: research
Chronic oxidative stress adaptation in head and neck cancer cells generates slow-cyclers with decreased tumour growth in vivo
CONCLUSIONS: Clinically, combination treatments together with cetuximab, an EGFR inhibitor, may overcome acquired oxidative stress resistance in HNC.PMID:37460712 | DOI:10.1038/s41416-023-02343-6
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Julia Berner Lea Miebach Marcel Kordt Christian Seebauer Anke Schmidt Michael Lalk Brigitte Vollmar Hans-Robert Metelmann Sander Bekeschus Source Type: research
Brain Metastasis Incidence and Patterns of Presentation After Definitive Treatment of Locally Advanced Non-Small Cell Lung Cancer: A Potential Argument for Brain Magnetic Resonance Imaging Surveillance
CONCLUSIONS: We identified a high rate of BMs, particularly in LC/NOS and adenocarcinoma histology NSCLC. The majority were symptomatic. These results provide rationale for post-CRT magnetic resonance imaging brain surveillance for patients at high risk of BM.PMID:37273925 | PMC:PMC10238260 | DOI:10.1016/j.adro.2022.101058
Source: Adv Data - June 5, 2023 Category: Epidemiology Authors: Joshua C Farris Ryan T Hughes Niema B Razavian Jane B Pearce Anna C Snavely Michael D Chan Cole R Steber C Marc Leyrer Paul M Bunch Jeffrey S Willey Michael K Farris Source Type: research
Diagnostic performance of FDG PET/MRI for cervical lymph node metastasis in patients with clinically N0 head and neck cancer
CONCLUSIONS: PET/MRI is more sensitive and has a higher NPV compared to MRI alone, while its sensitivity was found to be comparable to that of PET. In addition, with its ability to detect pathological N0 patients, PET/MRI may significantly decrease the number of unnecessary neck dissections.PMID:37259734 | DOI:10.26355/eurrev_202305_32459
Source: Pharmacological Reviews - June 1, 2023 Category: Drugs & Pharmacology Authors: S Cebeci U Aydos A Yeniceri D Pula M Duzlu L O Atay M Yilmaz Source Type: research
Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5T MR-Linear accelerator hybrid system: A prospective R-IDEAL Stage 2a imaging biomarker characterization/ pre-qualification study
CONCLUSION: Assessment of ADC kinetics at regular intervals throughout RT seems to be correlated with RT response. Further studies with larger cohorts and multi-institutional data are needed for validation of ΔADC as a model for prediction of response to RT.PMID:37205359 | PMC:PMC10187456 | DOI:10.1101/2023.05.04.23289527
Source: Cancer Control - May 19, 2023 Category: Cancer & Oncology Authors: Joint Head and Neck Radiation Therapy-MRI Development Cooperative MR-Linac Consortium Head and Neck Tumor Site Group Dina M El-Habashy Kareem A Wahid Renjie He Brigid McDonald Jillian Rigert Samuel J Mulder Tze Yee Lim Xin Wang Jinzhong Yang Yao Ding Moha Source Type: research
A case of coexistent poorly differentiated adenosquamous carcinoma (glassy cell carcinoma), usual-type adenocarcinoma, and squamous cell carcinoma in situ of the cervix
Med Mol Morphol. 2023 May 2. doi: 10.1007/s00795-023-00354-z. Online ahead of print.ABSTRACTPoorly differentiated adenosquamous carcinoma (glassy cell carcinoma) of the cervix is extremely rare, accounting for 1-2% of all cervical cancers. Herein, we report a case with coexistent poorly differentiated adenosquamous carcinoma (glassy cell carcinoma), "usual-type" adenocarcinoma, and squamous cell carcinoma in situ of the cervix. A female patient in her 60 s was referred to our hospital and diagnosed with poorly differentiated adenosquamous carcinoma based on cervical cytology and biopsy. The tumor was classified as clinical...
Source: Molecular Medicine - May 2, 2023 Category: Molecular Biology Authors: Kouki Habara Asami Nishikori Jin Kiyama Manami Nakashima Masanori Koda Kenji Sasaki Tomohisa Sakashita Norifumi Tanaka Shuji Yonehara Source Type: research
Imaging of Neck Nodes in Head and Neck Cancers - a Comprehensive Update
Clin Oncol (R Coll Radiol). 2023 Mar 27:S0936-6555(23)00119-X. doi: 10.1016/j.clon.2023.03.012. Online ahead of print.ABSTRACTCervical lymph node metastases from head and neck squamous cell cancers significantly reduce disease-free survival and worsen overall prognosis and, hence, deserve more aggressive management and follow-up. As per the eighth edition of the American Joint Committee on Cancer staging manual, extranodal extension, especially in human papillomavirus-negative cancers, has been incorporated in staging as it is important in deciding management and significantly impacts the outcome of head and neck squamous ...
Source: Cancer Control - April 15, 2023 Category: Cancer & Oncology Authors: K Bhattacharya A Mahajan R Vaish S Rane S Shukla A K D'Cruz Source Type: research
Estimated dose to site of loco-regional recurrence after radiotherapy in anal cancer using point of origin methods
CONCLUSION: The majority of LLRs were located within the high dose volume indicating radioresistance as the primary cause of recurrence in anal cancer. No difference between the use of COM and obs-PO was evident.PMID:36817982 | PMC:PMC9929855 | DOI:10.1016/j.phro.2023.100424
Source: Health Physics - February 23, 2023 Category: Physics Authors: Karen Lycke Wind Karen-Lise Garm Spindler Christina Maria Lutz Lars Nyvang Camilla Kronborg Source Type: research
Multi-parametric MRI without artificial erection for preoperative assessment of primary penile carcinoma: A pilot study on the correlation between imaging and histopathological findings
CONCLUSIONS: Good concordance was observed between MRI and histopathological findings. Our initial findings indicate that non-erectile mpMRI is useful in preoperative assessment of primary penile SCC.PMID:36793771 | PMC:PMC9922909 | DOI:10.1016/j.ejro.2023.100478
Source: Cancer Control - February 16, 2023 Category: Cancer & Oncology Authors: Marta D Switlyk Andreas Hopland Shivanthe Sivanesan Bj ørn Brennhovd Fredrik Ottosson Kjetil Berner Ulrika Axcrona Knut H Hole Source Type: research
Primary squamous cell carcinoma of the ovary accompanied by transition of a mucinous borderline ovarian tumor
This report describes a woman with a rare primary squamous cell carcinoma of the ovary accompanied by transition of a mucinous borderline ovarian tumor. A woman in her late 40s was referred for abdominal discomfort, which worsened during defecation. Pelvic magnetic resonance imaging showed a multiloculated cystic lesion in the left adnexa measuring approximately 7.5 × 9.5 × 7.0 cm. An intraoperatively obtained frozen biopsy sample of the mass in the left ovary was positive for malignancy, resulting in a surgical staging operation. The tumor was composed of squamous cell carcinoma and mucinous borderline tumor. There was ...
Source: Cell Research - February 3, 2023 Category: Cytology Authors: Seungeun Bak Ji Yun Hong Ji Woo Lee Soyoung Im Dong Choon Park Source Type: research
Surgical treatment and prognosis of posteriorly invading oral cancer: Potential clinical significance of pterygomandibular raphe
CONCLUSION: OSCCs with posterior invasion beyond the PMR showed a poor treatment outcome and, therefore, should be treated with caution. The initial surgery is especially important and must ensure local control. This study indicates that the PMR is an important criterion for surgical method determination and that invasion beyond the PMR is a predictor of local recurrence and poor prognosis.PMID:36643228 | PMC:PMC9831833 | DOI:10.1016/j.jds.2022.07.008
Source: Cancer Control - January 16, 2023 Category: Cancer & Oncology Authors: Mitsunobu Otsuru Souichi Yanamoto Tomofumi Naruse Keisuke Omori Kota Morishita Misa Sumi Masahiro Umeda Source Type: research
