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Evaluating a professional patient navigation intervention in a supportive care setting
ConclusionsThe intervention was perceived as valuable by both patients and healthcare professionals. The results may, however, been biased by the large number of patients who were omitted from participation due to logistical reasons.
Source: Supportive Care in Cancer - January 5, 2019 Category: Cancer & Oncology Source Type: research

What Has A.I. In Medicine Ever Done For Us? At Least 45 Things!
Remember Monty Python’s brilliant Life of Brian movie scene where the Palestinian insurgent commando, planning the abduction of Pilate’s wife in return for all the horrors they had to endure from the Roman Empire, asks the rhetorical question: what have the Romans ever done for us? With the hype and overmarketing, not to speak about the fears around A.I, we asked the same question. What has A.I. in medicine ever done for us? Well, we found at least 45 things. I have 45 responses to the pressing question on everyone’s mind who is interested in healthcare but tired of the hype or the doomsday scenarios around A.I.: ...
Source: The Medical Futurist - May 28, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine Future of Medicine administration AI cancer diagnostics digital health digital health technology Healthcare Innovation medical medical imaging Radiology treatment Source Type: blogs

Prognostic Value of Functional Assessment of Cancer Therapy-General (FACT-G) in Advanced Non-Small-Cell Lung Cancer Treated with Korean Medicine.
Conclusion: The FACT-G total score and PWB score as HRQoL measurements were significant prognostic factors for survival in advanced NSCLC patients treated with Korean medicine. This finding implies that the FACT-G can be used in clinical practice as a predictor of survival in patients with advanced NSCLC. PMID: 32454853 [PubMed - as supplied by publisher]
Source: Evidence-based Complementary and Alternative Medicine - May 27, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Supportive care and unmet needs in patients with melanoma: a mixed-methods systematic review
ConclusionMelanoma-specific care and unmet care needs were identified most commonly in the informational domain, followed by psychological, social and physical domains. Oncology practitioners should consider enhancing their supportive care interventions throughout the journey of patient with melanoma to reduce or address their unmet needs. The results of this mixed-methods systematic review warrant further research using robust study designs, melanoma-specific validated outcome measures and complete reporting of data in terms of disease stage.
Source: Supportive Care in Cancer - June 26, 2020 Category: Cancer & Oncology Source Type: research

Sentinel Node Imaging and Radioguided Surgery in the Era of SPECT/CT and PET/CT: Toward New Interventional Nuclear Medicine Strategies
We review recent technological advances and new clinical indications for sentinel node (SN) and radioguided surgery in order to delineate future tendencies of interventional nuclear medicine in this field. A literature research was performed in PubMed to select relevant articles to be used as key references for analysis of the current approaches and tendencies in SN and radioguided surgery, as well as the evolving contribution of nuclear medicine intervention techniques to the various clinical applications. For classic indications such as melanoma and breast cancer, the incorporation of the SN approach based on the combine...
Source: Clinical Nuclear Medicine - September 9, 2020 Category: Nuclear Medicine Tags: Opinion Paper/Commentary Source Type: research

Self-reported late effects and long-term follow-up care among 1889 long-term Norwegian Childhood, Adolescent, and Young Adult Cancer Survivors (the NOR-CAYACS study)
ConclusionsThe majority of survivors reported at least one late effect, but not receiving specific follow-up care for these. This indicates a need for structured models of long-term follow-up to ensure adequate access to care.
Source: Supportive Care in Cancer - October 2, 2020 Category: Cancer & Oncology Source Type: research

What Has A.I. In Medicine Ever Done For Us? At Least 50 Things!
Remember Monty Python’s brilliant Life of Brian movie scene where the Judean Jewish insurgent commando, planning the abduction of Pilate’s wife in return for all the horrors they had to endure from the Roman Empire, asks the rhetorical question: what have the Romans ever done for us? With the hype and overmarketing, not to speak about the fears around A.I, we asked the same question. What has A.I. in medicine ever done for us? Well, we found at least 50 things. I have 50 responses to the pressing question on everyone’s mind who is interested in healthcare but tired of the hype or the doomsday scenarios around A.I....
Source: The Medical Futurist - March 1, 2022 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine AI cancer diagnostics digital health Healthcare Innovation medical Radiology technology medical imaging treatment administration digital health technology Source Type: blogs

Online Readability Analysis: Mohs Micrographic Surgery Postsurgical Wound Care
CONCLUSIONS Although this level of readability is an improvement in online MMS postsurgical wound care information relative to prior literature, there is still considerable work to be done by the dermatologic community in improving the readability of online patient materials regarding MMS.
Source: Advances in Skin and Wound Care - March 29, 2022 Category: Dermatology Tags: ORIGINAL INVESTIGATIONS Source Type: research

Factors influencing cancer survivors ’ experiences with follow-up cancer care: results from the pan-Canadian Experiences of Cancer Patients in Transition Study survey
ConclusionWhile real-world experiences with follow-up cancer care in Canada are reported to be positive by most cancer survivors included in this study, we found differences exist based on individual and structural factors. A better understanding of the reasons for these differences is required to guide the provision of high-quality follow-up care that is adapted to the needs and resources of individuals and contexts.
Source: Supportive Care in Cancer - September 20, 2022 Category: Cancer & Oncology Source Type: research

The Picture With The Smile That Says So Much About Advances In Cancer Care
It was the picture (see below) that, to me, said it all: a 96 year old woman -- one of the first patients in the world to receive a brand new cancer drug--, and a large tumor on her neck had melted completely away. But it was the smile on her lips that you couldn't avoid noticing. Let's set the stage: You have spent the last 5 days in a large convention center at the Annual Meeting of the American Society of Clinical Oncology in Chicago running from presentation to presentation and meeting to meeting. You have heard more information presented in more rapid fire sequence than any human being can possibly absorb. You h...
Source: Dr. Len's Cancer Blog - June 4, 2014 Category: Cancer Authors: Dr. Len Tags: Access to care Cancer Care Media Medicare Medications Melanoma Other cancers Research Survivors Treatment Source Type: blogs

Current and future roles of targeted therapy and immunotherapy in advanced melanoma.
CONCLUSIONS: The immunotherapy ipilimumab and the MAPK-targeted inhibitors vemurafenib, dabrafenib, and trametinib have forever changed the treatment landscape for melanoma. Indeed, these new therapies have demonstrated long-term improvement in patient outcome, a benefit not afforded by traditional therapeutics. Important research continues on the molecular basis of melanoma, and new targets are likely to emerge. Other areas of work include optimization of sequencing and/or combination of current treatments, which may increase the number of patients who experience clinical benefit. PMID: 24684639 [PubMed - in process]
Source: Journal of Managed Care Pharmacy - November 14, 2014 Category: Drugs & Pharmacology Tags: J Manag Care Pharm Source Type: research

Cancer Risk Among People With Type 1 and Type 2 Diabetes: Disentangling True Associations, Detection Bias, and Reverse Causation.
CONCLUSIONS: Type 1 and type 2 diabetes are associated with an excess risk of incidence and mortality for overall and a number of site-specific cancers, and this is only partially explained by bias. We suggest that screening for cancers in diabetic patients is important. PMID: 25488912 [PubMed - as supplied by publisher]
Source: Diabetes Care - December 8, 2014 Category: Endocrinology Authors: Harding JL, Shaw JE, Peeters A, Cartensen B, Magliano DJ Tags: Diabetes Care Source Type: research

Revisiting Mortality Versus Survival In International Comparisons Of Cancer Care
No one doubts that the US spends more than any other country on health care.  Whether this higher spending produces commensurate health benefits, however, is far from certain. In the April 2012 issue of Health Affairs, Philipson et. al. make an intuitively persuasive observation, one which they summarize in their recent Health Affairs Blog post (authored by Goldman, Lakdawalla, and Philipson): “We find that survival after diagnosis rose more quickly in the U.S. than the E.U.” Given this observation, they go on to make an inference, namely that the US gets value from it additional expenditures on cancer care.  It wo...
Source: Health Affairs Blog - April 1, 2015 Category: Health Management Authors: H. Gilbert Welch and Elliott Fisher Tags: All Categories Comparative Effectiveness Europe Global Health Health Care Costs Policy Prevention Public Health Research Spending Source Type: blogs

A case of tardive dyskinesia in the last weeks of life.
We describe a patient with widely metastatic squamous cell carcinoma of the lung who developed severe TD when treated with chlorpromazine for severe hiccups. As his prognosis was only days to weeks, we were able to effectively suppress his TD with haloperidol. Hospice care emphasizes relief of suffering at the end of life, often at the expense of attention to long-range adverse effects, and this approach may be a viable management strategy for patients with TD and very limited prognosis. PMID: 26095485 [PubMed - in process]
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Epigenetic Profiling of H3K4Me3 Reveals Herbal Medicine Jinfukang-Induced Epigenetic Alteration Is Involved in Anti-Lung Cancer Activity.
Authors: Lu J, Zhang X, Shen T, Ma C, Wu J, Kong H, Tian J, Shao Z, Zhao X, Xu L Abstract Traditional Chinese medicine Jinfukang (JFK) has been clinically used for treating lung cancer. To examine whether epigenetic modifications are involved in its anticancer activity, we performed a global profiling analysis of H3K4Me3, an epigenomic marker associated with active gene expression, in JFK-treated lung cancer cells. We identified 11,670 genes with significantly altered status of H3K4Me3 modification following JFK treatment (P < 0.05). Gene Ontology analysis indicates that these genes are involved in tumor-related...
Source: Evidence-based Complementary and Alternative Medicine - April 20, 2016 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research