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Cancer: Colorectal Cancer
Therapy: Intensity-Modulated Radiation Therapy

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Total 70 results found since Jan 2013.

Relationship between seminal vesicle displacement and distribution of hydrogel spacer within the perirectal space in prostate radiotherapy
In conclusion, SV cranial displacement was influenced by HS lateral distribution of ≥1.00 cm in the upper two slices. Therefore, when the sigmoid colon or small bowel is depressed in rectovesical excavation and SV needs to be included in the target volume, HS insertion should be performed carefully.PMID:37719041 | PMC:PMC10502802 | DOI:10.3892/mco.2023.2674
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Kenji Makita Yasushi Hamamoto Hiromitsu Kanzaki Kei Nagasaki Katsuyoshi Hashine Source Type: research

Dosimetry and acute radiation enteritis comparison between prone and supine position in IMRT for gynecological cancers
CONCLUSION: Prone position in IMRT for gynecological cancers could significantly reduce radiation dose to the small bowel and colon, which would decrease the occurrence and severity of acute intestinal side effects possibly.PMID:37621141 | DOI:10.1002/acm2.14135
Source: Journal of Applied Clinical Medical Physics - August 25, 2023 Category: Physics Authors: Huamei Yan Manya Wu Wan Wang Donghui Wang Xiaoqing Huang Jie Dong Luxi Chen Zhenghuan Li Xiangying Xu Source Type: research

Cancer Control, Toxicity, and Secondary Malignancy Risks of Proton Radiation Therapy for Stage I-IIB Testicular Seminoma
CONCLUSIONS: Cancer control and toxicity outcomes using proton RT in stage I-IIB testicular seminoma are consistent with existing photon-based RT literature. However, proton RT may be associated with significantly lower SMN risks.PMID:37408671 | PMC:PMC10318216 | DOI:10.1016/j.adro.2023.101259
Source: Cancer Control - July 6, 2023 Category: Cancer & Oncology Authors: Russell Maxwell Yushi Chang Christina Paul David J Vaughn John P Christodouleas Source Type: research

In silico comparison of whole pelvis intensity-modulated photon versus proton therapy for the postoperative management of prostate cancer
CONCLUSION: IMPT provides comparable target coverage to IMRT when treating prostate cancer with WPRT in the postoperative setting while significantly reducing dose to OARs. These data can inform the future clinical management and delivery of post-prostatectomy irradiation for prostate cancer.PMID:37345868 | DOI:10.1080/0284186X.2023.2224925
Source: Acta Oncologica - June 22, 2023 Category: Cancer & Oncology Authors: Emile Gogineni Ian K Cruickshank Hao Chen Aditya Halthore Heng Li Curtiland Deville Source Type: research

Revisiting the Radical Radiotherapy-Radiochemotherapy Results in Anal Canal Cancers: (TROD Gastrointestinal Group Study 02-005)
CONCLUSION: Radiochemotherapy is the primary treatment for anal canal cancer and advanced radiotherapy techniques may increase survival by reducing side effects and improving treatment continuation. Higher treatment doses require further investigation. The efficacy of treatment can be improved by including patients treated with modern radiotherapy techniques in multicenter prospective studies using new and more effective chemotherapy and immunotherapy agents.PMID:37336706 | DOI:10.1016/j.clcc.2023.05.004
Source: Clinical Colorectal Cancer - June 19, 2023 Category: Cancer & Oncology Authors: Sule Karabulut Gul Huseyin Tepetam Ferah Yildiz Ilhami Er Didem Colpan Oksuz Murtaza Parvizi Ayse Sevgi Ozden Zumre Arican Alicikus Sezin Yuce Sari Omar Alomari Ilknur Bilkay Gorken Source Type: research

Long-Term Patient-Reported Quality of Life of Anal Cancer Survivors Treated with Intensity Modulated Radiation Therapy and Concurrent Chemotherapy: Results from a Prospective Phase II trial
CONCLUSIONS: When compared with historical data, IMRT is associated with reduced long-term impacts on QOL. The majority of patients treated with IMRT experienced clinically significant recovery of function and improvement in QOL over 5 years after completion of treatment. The study noticed that specific toxicities such as chronic diarrhea, fecal incontinence urinary and sexual dysfunction were primarily responsible for deterioration of the long-term QOL. Future research aimed at reducing such toxicities is needed to further improve long-term QOL in anal cancer.PMID:37148982 | DOI:10.1016/j.ijrobp.2023.04.023
Source: Cancer Control - May 6, 2023 Category: Cancer & Oncology Authors: Kurian Joseph Mustafa Al Balushi Sunita Ghosh Trevor Stenson Aswin Abraham Arun Elangovan Heather Warkentin Kim Paulson Keith Tankel Nawaid Usmani Diane Severin Dan Schiller Clarence Wong Karen Mulder Corinne Doll Karen King Tirath Nijjar Source Type: research

Validation of prediction models for radiation-induced late rectal bleeding: evidence from a large pooled population of prostate cancer patients
CONCLUSION: Five published NTCP models developed on non-contemporary cohorts were able to predict a relative increase in the toxicity response in a more recent validation population. Compared to QUANTEC findings, dosimetric results pointed toward mid-high doses of rectal DVH. The external validation cohort confirmed abdominal surgery and cardiovascular diseases as risk factors.PMID:36934896 | DOI:10.1016/j.radonc.2023.109628
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 19, 2023 Category: Radiology Authors: Alessandro Cicchetti Claudio Fiorino Martin A Ebert Jacopo Iacovacci Angel Kennedy David J Joseph James W Denham Vittorio Vavassori Gianni Fellin Cesare Cozzarini Claudio Degli Esposti Pietro Gabriele Fernando Munoz Barbara Avuzzi Riccardo Valdagni Tizian Source Type: research