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Total 440 results found since Jan 2013.
EBCOG position statement on Inequalities in screening for cervical and breast cancer
Eur J Obstet Gynecol Reprod Biol. 2023 Aug 30:S0301-2115(23)00692-9. doi: 10.1016/j.ejogrb.2023.08.386. Online ahead of print.ABSTRACTGynaecological cancers, namely breast and cervical cancer represent a high burden in women's health. It is well established that cervical and breast cancer screening programmes are effective in reducing morbidity and mortality. It is of the most importance to define strategies to provide a universal access to screening. In European countries, significant progress has been made over the past years concerning screening strategies, namely the choice of screening test, its frequency as well as t...
Source: Reproductive Biology - September 9, 2023 Category: Reproduction Medicine Authors: M árcia Vieira-Coimbra Nuno Nogueira-Martins Rafal Zadykowicz Hugo Rodrigues Gaspar Jean Calleja-Agius Maja Pakiz Sambit Mukhopadhyay Tahir Mahmood Source Type: research
Stimuli-Responsive Hydrogel Microcapsules Harnessing the COVID-19 Immune Response for Cancer Therapeutics
We present the development of stimuli-responsive microcapsules, loaded with a viral immunogenetic agent, harnessing the immune response against the Coronavirus Disease 2019, COVID-19, to selectively attack liver cancer cells (hepatoma) or recognize breast cancer or hepatoma, by expression of green fluorescence protein, GFP. The pH-responsive microcapsules, modified with DNA-tetrahedra nanostructures, increased hepatoma permeation by 50%. Incorporation of a GFP-encoding lentivirus vector inside the tumor-targeting pH-stimulated miRNA-triggered and Alpha-fetoprotein-dictated microcapsules enables the demonstration of neoplas...
Source: Angewandte Chemie - September 7, 2023 Category: Chemistry Authors: Amit Fischer Avner Ehrlich Yevgeni Plotkin Yu Ouyang Klil Asulin Ioannidis Konstantinos Chunhai Fan Yaakov Nahmias Itamar Willner Source Type: research
Provision of screening services for cervical and breast cancer - A scientific study commissioned by the European Board & amp; College of Obstetrics and Gynaecology (EBCOG)
CONCLUSIONS: There are discrepancies around gynaecological cancer screenings provision among EBCOG member countries. It is important to establish European recommendations about screening for gynaecological cancers, in order to standardize the access to equitable better health care in gynaecological cancers within Europe.PMID:37679212 | DOI:10.1016/j.ejogrb.2023.08.385
Source: Reproductive Biology - September 7, 2023 Category: Reproduction Medicine Authors: M árcia Vieira-Coimbra Nuno Nogueira-Martins Rafal Zadykowicz Hugo Rodrigues Gaspar Jean Calleja-Agius Maja Pakiz Sambit Mukhopadhyay Tahir Mahmood Source Type: research
Turning anecdotal irradiation-induced anti-cancer immune responses into reproducible in situ cancer vaccines via disulfiram/copper-mediated enhanced immunogenic cell death of breast cancer cells
In conclusion, our novel approach generated an anti-cancer immune response, resulting in a lack of or low tumor incidence post-rechallenge and robust AEs, i.e., the absence of or decreased spontaneous lung metastasis in tumor-bearing mice. This approach is readily translatable to clinical settings and may increase IR-induced AEs in cancer patients.PMID:37645899 | PMC:PMC10462241 | DOI:10.21203/rs.3.rs-3195392/v1
Source: Cell Research - August 30, 2023 Category: Cytology Authors: Xinhui Wang Wei Guo Lin Jia Ling Xie Juliann Kiang Yangyang Wang Fuyou Wang Zunwen Lin Enwen Wang Yida Zhang Peigen Huang Ting Sun Xiao Zhang Zhengying Bian Tiejun Tang Jingtian Guo Soldano Ferrone Source Type: research
Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research
Creation and characterization of a recombinant mammalian orthoreovirus expressing σ1 fusion proteins encoding human epidermal growth factor receptor 2 peptides
Virology. 2023 Aug 19;587:109871. doi: 10.1016/j.virol.2023.109871. Online ahead of print.ABSTRACTMammalian orthoreovirus (MRV) is an oncolytic virus that has been tested in over 30 clinical trials. Increased clinical success has been achieved when MRV is used in combination with other onco-immunotherapies. This has led the field to explore the creation of recombinant MRVs which incorporate immunotherapeutic sequences into the virus genome. This work focuses on creation and characterization of a recombinant MRV, S1/HER2nhd, which encodes a truncated σ1 protein fused in frame with three human epidermal growth factor recept...
Source: Virology - August 27, 2023 Category: Virology Authors: Nicole A Jandick Cathy L Miller Source Type: research
mRNA vaccine in cancer therapy: Current advance and future outlook
Clin Transl Med. 2023 Aug;13(8):e1384. doi: 10.1002/ctm2.1384.ABSTRACTMessenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that have shown great promise in the immunotherapy of a wide variety of infectious diseases and cancer. In the past 2 years, SARS-CoV-2 mRNA vaccines have contributed tremendously against SARS-CoV2, which has prompted the arrival of the mRNA vaccine research boom, especially in the research of cancer vaccines. Compared with conventional cancer vaccines, mRNA vaccines have significant advantages, including efficient production of protective immune responses, relatively low s...
Source: Clinical Breast Cancer - August 24, 2023 Category: Cancer & Oncology Authors: Youhuai Li Mina Wang Xueqiang Peng Yingying Yang Qishuang Chen Jiaxing Liu Qing She Jichao Tan Chuyuan Lou Zehuan Liao Xuexin Li Source Type: research
Breast cancer vaccines; A comprehensive and updated review
Pathol Res Pract. 2023 Aug 4;249:154735. doi: 10.1016/j.prp.2023.154735. Online ahead of print.ABSTRACTAccording to the International Agency for Research on Cancer, breast cancer is more common than lung cancer globally. By 2040, mortality from breast cancer will rise by 50% and 40%, respectively. Despite advances in chemotherapy, endocrine therapy, and HER2-targeted therapy, breast cancer metastases and recurrences remain challenging to treat. Cancer vaccines are an effective treatment option because they stimulate a long-lasting immune response that will eliminate tumor cells. In studies on the breast cancer vaccine, no ...
Source: Pathology, Research and Practice - August 23, 2023 Category: Pathology Authors: Sulieman Ibraheem Shelash Al-Hawary Ebraheem Abdu Musad Saleh Nodirjon Akhmetovich Mamajanov Nataliya S Gilmanova Hashem O Alsaab Adel Alghamdi Shakeel Ahmed Ansari Ahmed Hussien Radie Alawady Ali Hashiem Alsaalamy Ahmed Jaber Ibrahim Source Type: research
