Filtered By:
Cancer: Breast Cancer

This page shows you your search results in order of relevance. This is page number 11.

Order by Relevance | Date

Total 677 results found since Jan 2013.

Still a place for hormone replacement therapy?
Abstract Hormone replacement therapy (HRT) remains the most efficient treatment to alleviate climacteric symptoms. The drastic decline in their prescription following the WHI is not fully justified. Benefits might be more important than harm in women 50-60 years. French way of treatment does not increase the risk in thrombosis nor stroke and breast cancer risk is less important than with other regimen. One of the major benefits of HRT is the decrease in type 2 diabetes with all the treatments including the French ones. The results of the American randomized trials cannot be fully extrapolated to young postmenopa...
Source: Presse Medicale - November 7, 2013 Category: Journals (General) Authors: Gompel A Tags: Presse Med Source Type: research

Effects of Catecholamines on Microcirculation During General Inhalation Anesthesia
Conclusions: During general anesthesia with sevoflurane, the infusion of clinical dosages of norepinephrine and dobutamine did not alter sublingual perfusion, although the expected systemic hemodynamic alterations were induced.
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 22, 2013 Category: Anesthesiology Authors: Paolo Chiarandini, Livia Pompei, Maria Gabriella Costa, Luigi Vetrugno, Fortunato Ronga, Roberta Contin, Fabio Rosa, Giorgio Della Rocca Tags: Original Article Source Type: research

Sudden cardiac death: a critical appraisal of the implantable cardioverter defibrillator
Summary ImportanceApproximately 350,000 Americans still die of sudden cardiac death each year. This exceeds the number of patients who die annually from stroke, lung cancer, breast cancer and AIDS combined. ObjectiveThis review aims to trace the history of implantable cardioverter defibrillators (ICD) with reference to landmark trials and their influence on the formulation of Medicare guidelines for ICD implantation criteria. This paper will also discuss the cost‐effectiveness of ICDs and the quality of life after implantation. The reasons for the disparity between guidelines for implantation and actual clinical practice...
Source: International Journal of Clinical Practice - December 22, 2013 Category: Internal Medicine Authors: A. Rajabali, E. K. Heist Tags: Review Article Source Type: research

Adiponectin as a routine clinical biomarker.
Abstract Adiponectin is a protein synthesized and secreted predominantly by adipocytes into the peripheral blood. However, circulating adiponectin level is inversely related with body weight, especially visceral fat accumulation. The mechanism of this paradoxical relation remains obscure. Low circulating adiponectin concentrations (hypoadiponectinemia; <4 μg/mL) are associated with a variety of diseases, including dysmetabolism (type 2 diabetes, insulin resistance, hypertension, dyslipidemia, metabolic syndrome, hyperuricemia), atherosclerosis (coronary artery disease, stroke, peripheral artery disease), slee...
Source: Clin Med Res - January 1, 2014 Category: Research Authors: Kishida K, Funahashi T, Shimomura I Tags: Best Pract Res Clin Endocrinol Metab Source Type: research

Clinical Features of Radiation-induced Carotid Atherosclerosis
Abstract: Carotid arteries frequently receive significant incidental doses of radiation during the treatment of malignant diseases, including head and neck cancer, breast cancer and lymphoma. Vascular injury after treatment may result in carotid artery stenosis and increased risk of neurological sequelae, such as stroke and transient ischaemic attack. The long latent interval from treatment to the development of clinical complications makes investigation of this process difficult, particularly in regard to the design of interventional clinical studies. Nevertheless, there is compelling clinical evidence that radiation cont...
Source: Clinical Oncology - November 4, 2013 Category: Radiology Authors: D.M. Gujral, B.N. Shah, N.S. Chahal, R. Senior, K.J. Harrington, C.M. Nutting Tags: Overview Source Type: research

Multifrequency Electrical Impedance Tomography Using Spectral Constraints
We present a method for performing MFEIT using spectral constraints. Boundary voltage data is employed directly to reconstruct the volume fraction distribution of component tissues using a nonlinear method. Given that the reconstructed parameter is frequency independent, this approach allows for the simultaneous use of all multifrequency data, thus reducing the degrees of freedom of the reconstruction problem. Furthermore, this method allows for the use of frequency difference data in a nonlinear reconstruction algorithm. Results from empirical phantom measurements suggest that our fraction reconstruction method points to ...
Source: IEE Transactions on Medical Imaging - February 1, 2014 Category: Biomedical Engineering Source Type: research

Long‐term safety of unopposed estrogen used by women surviving myocardial infarction: 14‐year follow‐up of the ESPRIT randomised controlled trial
ConclusionsThese results suggest that unopposed estrogen may be used safely by women with an intact uterus surviving a first myocardial infarction.
Source: BJOG: An International Journal of Obstetrics and Gynaecology - February 18, 2014 Category: OBGYN Authors: N Cherry, R McNamee, A Heagerty, H Kitchener, P Hannaford Tags: Original Article Source Type: research

Long-term safety of unopposed estrogen used by women surviving myocardial infarction: 14-year follow-up of the ESPRIT randomised controlled trial.
CONCLUSIONS: These results suggest that unopposed estrogen may be used safely by women with an intact uterus surviving a first myocardial infarction. PMID: 24533510 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 18, 2014 Category: OBGYN Authors: Cherry N, McNamee R, Heagerty A, Kitchener H, Hannaford P Tags: BJOG Source Type: research

Daily calcium intake in excess of 1400 mg is associated with increased all-cause and cardiovascular disease mortality in women
Commentary on: Michaëlsson K, Melhus H, Warensjö Lemming E, et al.. Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study. BMJ 2013;346:f228. Implications for practice and research Greater calcium intake is encouraged for bone health, but has unclear cardiovascular consequences. In a large cohort of Swedish women, total calcium intake of <600 or ≥1400 mg/day was associated with an increased risk of total mortality (TM) and cardiovascular disease mortality (CVDM). It is important to emphasise adequate dietary calcium intake in...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Sesso, H. D., Wang, L. Tags: Drugs: cardiovascular system, Stroke, Diet, Breast cancer, Ischaemic heart disease, Clinical diagnostic tests Primary healthcare Source Type: research

Urban greenways have the potential to increase physical activity levels cost-effectively
Conclusion: The Greenway intervention could be cost-effective at improving physical activity levels. Although the direct health gains are predicted to be small for any individual, summed over an entire population, they are substantial. In addition, the Greenway is likely to have much wider benefits beyond health.
Source: The European Journal of Public Health - March 26, 2014 Category: Journals (General) Authors: Dallat, M. A. T., Soerjomataram, I., Hunter, R. F., Tully, M. A., Cairns, K. J., Kee, F. Tags: Obesity, physical activity Source Type: research

NICE: 'schools should provide morning-after pill'
Conclusion Everyone makes mistakes, but if you find yourself relying on the morning-after pill as a regular method of contraception, you may want to speak to a healthcare professional about what would be the most suitable form of ongoing contraception for you to use. This could include methods that do not involve needing to take a daily pill, such as contraceptive patches, injections or an implant. However, none of these methods will protect you against sexually transmitted infections (STIs). Condoms are cheap, free of side effects and they will protect you against STIs such as chlamydia. For more information about your ...
Source: NHS News Feed - March 26, 2014 Category: Consumer Health News Tags: QA articles Pregnancy/child Source Type: news

Clinical prediction rules in practice: review of clinical guidelines and survey of GPs.
CONCLUSION: GPs use CPRs to guide management but also to comply with local policy requirements. Future research could focus on which clinical areas clinicians would most benefit from CPRs and promoting the use of robust, externally validated CPRs. PMID: 24686888 [PubMed - in process]
Source: The British Journal of General Practice - April 1, 2014 Category: Primary Care Authors: Plüddemann A, Wallace E, Bankhead C, Keogh C, Van der Windt D, Lasserson D, Galvin R, Moschetti I, Kearley K, O'Brien K, Sanders S, Mallett S, Malanda U, Thompson M, Fahey T, Stevens R Tags: Br J Gen Pract Source Type: research

Phytochemical constituents, nutritional values, phenolics, flavonols, flavonoids, antioxidant and cytotoxicity studies on Phaleria macrocarpa (Scheff.) Boerl fruits
Conclusion: The methanol extract and the ethyl acetate fraction of P. macrocarpa fruits exhibited good nutritional values, good antioxidant and cytotoxic activities, and merits further investigation to identify the specific compound(s) responsible for these activities.
Source: BMC Complementary and Alternative Medicine - May 8, 2014 Category: Complementary Medicine Authors: Ma Ma LaySaiful Anuar KarsaniSadegh MohajerSri Nurestri Abd Malek Source Type: research

Correspondence Radiotherapy for breast cancer, the TARGIT-A trial
Javant Vaidya and colleagues report an increased risk of non-breast cancer deaths with external beam radiotherapy (EBRT) compared with intraoperative radiotherapy, highlighting the difference in cardiac events in the two treatment groups. Although the log-rank statistics show a significant difference in non-breast cancer deaths in the EBRT group, these deaths included stroke, bowel ischaemia, and other events unrelated to breast irradiation. Therefore, the number of cardiac events are small, and to suggest that the risk of cardiac death differs between EBRT and intraoperative radiotherapy would be premature.
Source: LANCET - May 16, 2014 Category: Journals (General) Authors: Penny Mackenzie, Anthony Fyles, Caroline Chung Tags: Correspondence Source Type: research

Republished: Paget's disease of bone: clinical review and update
Paget's disease (PD) is a focal disorder of bone remodelling that occurs commonly in older people. In this article, we review clinical aspects of PD with an emphasis on recent findings. The epidemiology of PD appears to be changing rapidly, with several groups in different parts of the world reporting a marked reduction in the prevalence and incidence of PD, as well as in the severity of disease seen by clinicians. These findings seem most likely to be caused by changes in exposure to unknown environmental factors that have a role in the development of PD. However, genetic factors are also important. Mutations in SQSTM1 oc...
Source: Postgraduate Medical Journal - May 17, 2014 Category: Journals (General) Authors: Bolland, M. J., Cundy, T. Tags: Pain (neurology), Stroke, Breast cancer, Epidemiology, Calcium and bone Republished best practice Source Type: research