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In assessing risk of hormone therapy for menopause, dose — not form — matters
FINDINGSWhen it comes to assessing the risk of estrogen therapy for menopause, how the therapy is delivered — taking a pill versus wearing a patch on one’s skin — doesn’t affect risk or benefit, researchers at UCLA and elsewhere have found. But with the commonly used conjugated equine estrogen, plus progestogen, the dosage does. Higher doses, especially over time, are associated with greater risk of problems, including heart disease and some types of cancer, especially among obese women.BACKGROUNDThe Women ’s Health Initiative established the potential of estrogen therapy to increase or decrease the risk of strok...
Source: UCLA Newsroom: Health Sciences - July 27, 2017 Category: Universities & Medical Training Source Type: news

Luteolin: How To Reduce Breast Cancer Risk
More than 100 women die of breast cancer in the U.S. every day. It's the second leading cause of cancer deaths in American women. But in my opinion, many of those women really die of a tragic medical error. Let me explain… Millions of women in the U.S. have taken Big Pharma's hormone replacement therapy (HRT). Their doctors prescribe it to try to relieve the symptoms of menopause. Like hot flashes, night sweats, mood swings and weight gain. But what the drug companies try to pass off as hormones are actually synthetic concoctions. They are fake versions of the estrogen and progesterone that your body makes n...
Source: Al Sears, MD Natural Remedies - June 23, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Predictors of the effectiveness of accreditation on hospital performance: A nationwide stepped-wedge study
ConclusionHospital characteristics were not found to be predictors for the effects of accreditation, whereas conditions and types of care to some extent predicted the effectiveness.
Source: International Journal for Quality in Health Care - May 2, 2017 Category: International Medicine & Public Health Source Type: research

Abstract IA22: Using risk assessment tools to motivate behavior change
Epidemiology identifies risk factors for cancer and other diseases based on the idea that conveying such information to healthcare providers, the general public, and policy makers will result in population-wide improvements in healthy behaviors and, consequently, population-wide improvements in health outcomes. These actions assume that the audience understands and uses the information to make health-related decisions. However, the language of epidemiology, which is steeped in probabilistic thinking, is not necessarily the language of the general public. Furthermore, growing evidence suggests that the language of epidemiol...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Waters, E. A. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Oral Presentations - Invited Abstracts Source Type: research

Mind the Treatment Gap
getty images/ istock photoBy Vani S. Kulkarni and Raghav GaihaPHILADELPHIA AND NEW DELHI, Apr 14 2017 (IPS)Implementation of the Mental Healthcare Act will require a restructuring of health-care services The Mental Healthcare Bill, 2016, which was passed in the Lok Sabha on March 27, 2017, has been hailed as a momentous reform. According to the Bill, every person will have the right to access mental health care operated or funded by the government; good quality and affordable health care; equality of treatment and protection from inhuman practices; access to legal services; and right to complain against coercion and cruelt...
Source: IPS Inter Press Service - Health - April 14, 2017 Category: Global & Universal Authors: Vani Kulkarni and Raghav Gaiha Tags: Asia-Pacific Development & Aid Gender Gender Violence Headlines Health Human Rights Women's Health Source Type: news

MassDevice.com +5 | The top 5 medtech stories for April 11, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Stimwave wins Australian regulatory nod for Freedom SCS Stimwave Technologies said late last week it won approval from the Australian Therapeutic Goods Administration for its Freedom spinal cord stimulation system, and launched ...
Source: Mass Device - April 11, 2017 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Women ’s Health Policies Should Focus on NCDs
Professor Robyn Norton, co-founder and Principal Director of the George Institute for Global Health. Credit: Neena Bhandari/IPSBy Neena BhandariSYDNEY, Apr 11 2017 (IPS)Science and medicine were not subjects of dinnertime conversations in the Norton household in Christchurch, New Zealand, but Professor Robyn Norton grew up observing her parents’ commitment to equity and social justice in improving people’s lives. It left an indelible impression on her young mind.Her high school years coincided with the women’s movement reaching its peak. She got drawn into thinking about addressing women’s health issues and moved t...
Source: IPS Inter Press Service - Health - April 11, 2017 Category: Global & Universal Authors: Neena Bhandari Tags: Asia-Pacific Featured Global Headlines Health Poverty & SDGs Women's Health Non-communicable Diseases (NCDs) Source Type: news

Mangosteen: The Cancer-Fighting Superfruit
  If you're a woman with a family history of breast cancer, your doctor may recommend you start taking a toxic chemo drug like tamoxifen to lower your risk of developing the disease. Even if you have no signs or symptoms of cancer. Tamoxifen is what's known as a chemopreventive agent. That's a fancy phrase that means it's something that prevents cancer from forming. But its track record isn't all that impressive. Trials found that for every 1,000 women who take the drugs, only 21 to 35 cases of cancer would be prevented. And the side effects are downright terrifying. Bone pain, blood clots, increas...
Source: Al Sears, MD Natural Remedies - March 23, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Work after age 65: A prospective study of Australian men and women.
CONCLUSION: This study quantifies the importance of education and health factors in determining continued participation of Australian men and women in paid work in later life. These factors need to be considered for policies aiming to increase workforce participation beyond 65 years of age. PMID: 28272777 [PubMed - as supplied by publisher]
Source: Australasian Journal on Ageing - March 7, 2017 Category: Geriatrics Authors: Majeed T, Forder PM, Tavener M, Vo K, Byles J Tags: Australas J Ageing Source Type: research

Mediterranean diet may reduce risk of form of breast cancer – study
Eating plenty of nuts, fruit and fish may cut risk of getting oestrogen-receptor-negative cancer, Dutch research findsFollowing aMediterranean diet could help reduce the risk of contracting one of the worst types of breast cancer by 40%, according to a large study for the World Cancer Research Fund.The Mediterranean diet, which is rich in olive oil, fish, fruit, nuts, vegetables and wholegrains, has well-publicised benefits, includingreducing the risk of stroke and heart disease.Continue reading...
Source: Guardian Unlimited Science - March 6, 2017 Category: Science Authors: Haroon Siddique Tags: Breast cancer Cancer research Health & wellbeing Diets and dieting Life and style Science Society Medical research Source Type: news

Phaleria macrocarpa (Boerl.) Fruit induce G0/G1 and G2/M cell cycle arrest and apoptosis through mitochondria-mediated pathway in MDA-MB-231 Human Breast Cancer Cell
Conclusion The results indicated that PMEAF treatment induced apoptosis in MDA-MB-231 cells through intrinsic mitochondrial related pathway with the participation of pro and anti-apoptotic proteins, caspases, G0/G1 and G2/M-phases cell cycle arrest by p53-mediated mechanism. Graphical abstract
Source: Journal of Ethnopharmacology - March 1, 2017 Category: Drugs & Pharmacology Source Type: research

Abstract P6-07-12: A physical activity and dietary counseling intervention in breast cancer survivors and changes in known and novel prognostic biomarkers
High rates of overweight/obesity are commonly seen in breast cancer (BC) survivors. Observational data show an association between post-treatment increased weight and lack of physical activity (PA) and risk of BC recurrence and death. Increases in prognostic inflammatory associated biomarkers (BM) such as interleukin-6 (IL6) and C-reactive protein (CRP), and their downstream effects, are linked to overweight/obesity and provide a potential mechanistic explanation for this increase in recurrence risk, but studies are mixed regarding the effect of lifestyle interventions on these BM. In addition, better BM may exist. The Get...
Source: Cancer Research - February 28, 2017 Category: Cancer & Oncology Authors: LL Peterson, ME Ford, MJ Gregoski, KD Knight, EJ Hilton, G Magwood, DP Turner Tags: Poster Session Abstracts Source Type: research

Exercise 'most proven method' to prevent return of breast cancer
Conclusion This was a helpful summary of recent research into how lifestyle changes impact on the risk of breast cancer returning, but it does have some limitations. Researching lifestyle factors separately is always difficult as they tend to clump together, making it difficult to pick apart individual factors. For example, people who are more physically active tend to have a healthier diet and are less likely to drink excessive amounts of alcohol or smoke. While the researchers say many studies attempt to make adjustments for these confounding factors, it is difficult to know which studies did this and how successful they...
Source: NHS News Feed - February 22, 2017 Category: Consumer Health News Tags: Cancer QA articles Lifestyle/exercise Source Type: news

Abstract P5-08-06: Impact of a decision-support tool on the utilization of colony-stimulating factors and incidence of febrile neutropenia among patients with breast cancer
High rates of overweight/obesity are commonly seen in breast cancer (BC) survivors. Observational data show an association between post-treatment increased weight and lack of physical activity (PA) and risk of BC recurrence and death. Increases in prognostic inflammatory associated biomarkers (BM) such as interleukin-6 (IL6) and C-reactive protein (CRP), and their downstream effects, are linked to overweight/obesity and provide a potential mechanistic explanation for this increase in recurrence risk, but studies are mixed regarding the effect of lifestyle interventions on these BM. In addition, better BM may exist. The Get...
Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: G Adeboyeje, A Agiro, A Goodwin, A DeVries, J Malin Tags: Poster Session Abstracts Source Type: research

Abstract PD4-07: Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population study
Conclusions: The occurrence of MI is very low in this cohort (4.4%), reassuring the clinicians that the older adults with comorbidities may not be at a higher risk of MI with adjuvant endocrine therapy. However, the confidence interval for the hazard ratio of AIs vs Tamoxifen is very wide, indicating that a larger sample may be needed for the power of the study to be conclusive.Citation Format: Kamaraju S, Smith E, Shi Y, Laud P, Neuner J. Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population study [abstract]. In: Proceedings of the Thirty-Ninth Annual C...
Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: S Kamaraju, E Smith, Y Shi, P Laud, J Neuner Tags: Poster Discussion Abstracts Source Type: research