Exercise 'most proven method' to prevent return of breast cancer
Conclusion This was a helpful summary of recent research into how lifestyle changes impact on the risk of breast cancer returning, but it does have some limitations. Researching lifestyle factors separately is always difficult as they tend to clump together, making it difficult to pick apart individual factors. For example, people who are more physically active tend to have a healthier diet and are less likely to drink excessive amounts of alcohol or smoke. While the researchers say many studies attempt to make adjustments for these confounding factors, it is difficult to know which studies did this and how successful they were. It is also possible that women who did not exercise were unable to because of adverse effects from their breast cancer treatment. There is also the fact that lifestyle factors were only looked at after breast cancer diagnosis, when lifestyle before diagnosis might have long term effects. Still, the conclusion that regular exercise appears to be the best option seems reasonable and appropriate. Aside from cancer prevention, regular exercise can also help reduce the risk of other chronic diseases, such as heart disease. Read more about the benefits of exercise. Links To The Headlines Brisk 30-minute walk a day ‘STOPS killer breast cancer returning’. The Sun, February 21 2017 Boozing, weight gain and failing to exercise INCREASES the risk of breast cancer returning, experts say. Mail Online, February 21 2017 Links To Science Hamer J, ...
ConclusionsTrabectedin, in combination with PLD, may have clinical benefits in Japanese patients with relapsed advanced ovarian cancer. The recommended dosage of trabectedin for further study in this population is 1.1 mg/m2 once every 21 days.Clinical trial registration number: JapicCTI-163164
This study aimed to evaluate the correlation between clinicopathologic features and serum zinc levels in patients who underwent gastrectomy for gastric cancer.MethodsThe study enrolled 617 patients who underwent gastrectomy for gastric cancer at the Kochi Medical School. Clinical data were obtained to investigate associations between clinicopathological features, including nutritional indicators and serum zinc levels. Serum zinc deficiency was defined as serum zinc level
AbstractBackgroundA significant number of non-small cell lung cancer (NSCLC) patients develop osteogenic metastases (OMs) and/or brain metastases (BMs) after surgery, however, routine chest computed tomography (CT) sometimes fails to diagnose these recurrences. We investigated the incidence of BMs and OMs after pulmonary resection and aimed to identify candidates who can benefit from brain magnetic resonance imaging (MRI) and18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) in addition to CT.MethodsWe retrospectively reviewed medical records of 1099 NSCLC patients who underwent pulmonary resection between 2002 ...
AbstractBackgroundThe prognosis of patients with recurrence of uterine cervical cancer after definitive radiotherapy and the efficacy of local salvage therapy for recurrence were evaluated.MethodsWe retrospectively reviewed 110 patients who were treated with definitive radiotherapy/chemoradiotherapy for uterine cervical cancer between 2008 and 2017 at our institution. Local salvage therapy was defined as any surgery or radiotherapy described in the medical record as intended for local control or cure.ResultsWe identified 25 patients who developed recurrence after definitive radiotherapy/chemoradiotherapy. The median follow...
ConclusionThe presence of incurable locoregional disease had a significant prognostic impact, whereas the number of distant metastatic sites had no prognostic impact. Liver metastasis was a poor prognostic factor for recurrent/metastatic squamous cell carcinoma of the head and neck.
ConclusionWhile the real-world overall survival in Japanese patients with mRCC in the targeted therapy era improved compared to that previously reported in the cytokine era, there was no clear difference in the survival of poor risk patients between these eras. There were no differences in the superiority among the models.
ConclusionsRM-1929 photoimmunotherapy showed a manageable safety profile in rHNSCC. Tumor response in these heavily pre-treated patients was clinically meaningful and warrants further investigation.Clinical trial registrationThe trial was registered with the Japanese registry of clinical trials as jRCT2031200133.
ConclusionsThere was no difference in OS between irinotecan and paclitaxel no in OS prolongation of S-1 combination therapy in second-line chemotherapy.
Conclusions: There is wide variation in anesthesia technique and hemodynamic management during EVT for AIS, and no consensus on the choice of, or preferred medications for, GA or CS, or target blood pressure and management of hypotension during the procedure.
We examined parents’ structural and cognitive social capital using a self-report questionnaire.ResultsMultiple logistic regression analysis revealed associations between parents ’ social capital and children’s BMI. Seventy-two (20.2%) of the children had poor BMI (body mass index; overweight or thin). Interpersonal trust was significantly associated with normal BMI in children after adjustment for all confounding factors (OR 2.68; 95% CI, 1.33–5.44; P = .006) and was independently associated with other social capital factors, including norm of reciprocity (OR 3.38; 95% CI, 1.68–6.79; P
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