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Condition: Diabetes
Cancer: Breast Cancer
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Total 696 results found since Jan 2013.
Medicinal Aspects of PTP 1B Inhibitors as Anti-Breast Cancer Agents: An Overview
This study will provide significant information to the researchers developing PTP1B inhibitors for breast cancer treatment.PMID:37711015 | DOI:10.2174/0929867331666230914103645
Source: Current Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Rakesh Khator Avadh Biharee Neha Bhatia Swanand Kulkarni Yogesh Singh Chandrabose Karthikeyan Akhlesh Kumar Jain Suresh Thareja Source Type: research
Impact of obesity on female puberty and pubertal disorders
Best Pract Res Clin Obstet Gynaecol. 2023 Aug 10;91:102400. doi: 10.1016/j.bpobgyn.2023.102400. Online ahead of print.ABSTRACTThe worldwide epidemic of obesity appears to be one of the crucial health problems. One-third of children and adolescents in the United States are classified as either overweight or obese and 6% of adolescents are severely obese. With the development of high technology, children, and adolescents, spend more time in sedentary life. Together with the availability of consuming fast caloric food, it is almost unavoidable to get an imbalance between caloric intake and caloric expenditure of energy, resul...
Source: Clinical Genitourinary Cancer - September 14, 2023 Category: Cancer & Oncology Authors: Dvora Bauman Source Type: research
Nipple-Sparing Mastectomies in Patients over the Age of 60 Years: Factors Associated with Surgical Outcomes
CONCLUSIONS: Our data support NSM in patients over the age of 60 years with acceptable outcomes within the standard of care. Locoregional recurrence was within the cited range of 0-5%, and only diabetes and prior radiation were associated with reconstructive complications. NSM should thus be offered when appropriate regardless of increased age to achieve oncologic and reconstructive goals.PMID:37700172 | DOI:10.1245/s10434-023-14278-6
Source: Ann Oncol - September 12, 2023 Category: Cancer & Oncology Authors: Nisha Parmeshwar Catherine L Dugan Laura L Barnes Justin K Cheng Anne K Patterson Amanda Miller Rita Mukhtar Merisa Piper Source Type: research
Comorbidity in patients with Lichen sclerosus: a retrospective cohort study
This study confirmed the association between LS and vulvar cancer (OR = 17.4; 95% CI 12.1-25.3), penis cancer (OR = 9.1; 95% CI 4.3-18.9), prostate cancer (OR = 2.0; 95% CI 1.6-2.4) and breast cancer (OR = 1.6; 95% CI 1.4-1.8). LS was also associated with Crohn´s disease (OR = 2.0; 95% CI 1.6-2.6) and diabetes mellitus type 1 (OR = 1.9; 95% CI 1.6-2.1). The present study revealed novel important data regarding the association of LS with cancer and autoimmune diseases, emphasising the importance of sufficient treatment and follow-up of patients with LS. However, future studies are needed to confirm these results and the po...
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Sandra Jerkovic Gulin Filippa Lundin Oliver Seifert Source Type: research
Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer
J Clin Oncol. 2023 Sep 11:JCO2300296. doi: 10.1200/JCO.23.00296. Online ahead of print.ABSTRACTClinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned coprimary or secondary analyses are not yet available. Clinical trial updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported.Metformin has been associated with lower cancer risk in epidemiologic and preclinical research. In the MA.32 rando...
Source: Clinical Breast Cancer - September 11, 2023 Category: Cancer & Oncology Authors: Pamela J Goodwin Bingshu E Chen Karen A Gelmon Timothy J Whelan Marguerite Ennis Julie Lemieux Jennifer A Ligibel Dawn L Hershman Ingrid A Mayer Timothy J Hobday Judith M Bliss Priya Rastogi Manuela Rabaglio-Poretti Alastair M Thompson Daniel W Rea Paul M Source Type: research
Benefits of Soybean in the Era of Precision Medicine: A Review of Clinical Evidence
J Microbiol Biotechnol. 2023 Aug 28;33(12):1-11. doi: 10.4014/jmb.2308.08016. Online ahead of print.ABSTRACTSoybean (Glycine max) is an important ingredient of cuisines worldwide. While there is a wealth of evidence that soybean could be a good source of macronutrients and phytochemicals with healthpromoting effects, concerns regarding adverse effects have been raised. In this work, we reviewed the current clinical evidence focusing on the benefits and risks of soybean ingredients. In breast, prostate, colorectal, ovarian, and lung cancer, epidemiological studies showed an inverse association between soybean food intake an...
Source: Journal of Microbiology and Biotechnology - September 7, 2023 Category: Biotechnology Authors: Jung Hyun Kang Zigang Dong Seung Ho Shin Source Type: research
