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Cancer: Childhood Cancer

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Total 243 results found since Jan 2013.

Drugs to be offered to women at high risk of breast cancer
The National Institute of Health and Care Excellence (NICE) has today released updated guidelines on the care of women who are at increased risk of breast cancer due to their family history. One of the main changes to the original guidance from 2004 is that NICE now recommends drug treatment with tamoxifen or raloxifene to reduce risk of breast cancer in a specific group of women who are at high risk of breast cancer and have not had the disease. They say that these treatments could help prevent breast cancer in about 488,000 women aged 35 years and older. The updated guideline has also made changes to the recommende...
Source: NHS News Feed - June 25, 2013 Category: Consumer Health News Tags: Cancer Medical practice QA articles Source Type: news

Group Launches Initiative to Address Childhood Obesity
Two groups, Eat Well Play More Vermont and Live Healthy Vermont, are joining forces to lead the policy work in Vermont’s fight against childhood obesity, which is connected to increased risk for at least 20 chronic diseases, like heart disease, stroke, diabetes and cancer, said Tina Zuk, the government relations director for the American Heart Association.
Source: RWJF News Digest - Childhood Obesity - October 15, 2013 Category: Eating Disorders and Weight Management Source Type: news

Treatment-related cardiotoxicity in survivors of childhood cancer
Nature Reviews Clinical Oncology 10, 697 (2013). doi:10.1038/nrclinonc.2013.195 Authors: Steven E. Lipshultz, Thomas R. Cochran, Vivian I. Franco & Tracie L. Miller Treatment advances and higher participation rates in clinical trials have rapidly increased the number of survivors of childhood cancer. However, chemotherapy and radiation treatments are cardiotoxic and can cause cardiomyopathy, conduction defects, myocardial infarction, hypertension, stroke, pulmonary oedema, dyspnoea and exercise intolerance later in life.
Source: Nature Clinical Practice Oncology - October 29, 2013 Category: Cancer & Oncology Authors: Steven E. LipshultzThomas R. CochranVivian I. FrancoTracie L. Miller Tags: Review Source Type: research

Fruits And Vegetables May Not Prevent Cancer
BOSTON (CBS) – Who hasn’t heard that eating a lot of fruits and vegetables can help you fend off cancer? Dr. Walter Willett, a leading expert on nutrition and health at the Harvard School of Public Health, says your diet may play less of a role in cancer prevention as originally thought. “As better data have come along,” he says, “the benefits for cancer don’t look nearly as impressive.” And fat doesn’t appear to be as bad as once thought for promoting cancer either. “There had been a strong belief that fat in our diet was the major cause of breast cancer, colon cancer, prostate cancer and oth...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 5, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Cancer Dr. Mallika Marshall Dr. Walter Willett Fruit Vegetables Source Type: news

Managing Chemotherapy-Related Cardiotoxicity in Survivors of Childhood Cancers.
Abstract In the US, children diagnosed with cancer are living longer, but not without consequences from the same drugs that cured their cancer. In these patients, cardiovascular disease is the leading cause of non-cancer-related morbidity and mortality. Although this review focuses on anthracycline-related cardiomyopathy in childhood cancer survivors, the global lifetime risk of other cardiovascular diseases such as atherosclerosis, arrhythmias and intracardiac conduction abnormalities, hypertension, and stroke also are increased. Besides anthracyclines, newer molecularly targeted agents, such as vascular endothel...
Source: Paediatric Drugs - August 19, 2014 Category: Pediatrics Authors: Lipshultz SE, Diamond MB, Franco VI, Aggarwal S, Leger K, Santos MV, Sallan SE, Chow EJ Tags: Paediatr Drugs Source Type: research

The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure.
Abstract Since the modern era of cancer chemotherapy that began in the mid 1940's, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80%. Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk. Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease (CAD), and valvular disease. Their cardiac mortality is 8.2 times ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 12, 2014 Category: Physiology Authors: Lindsey ML, Lange RA, Parsons H, Andrews T, Aune GJ Tags: Am J Physiol Heart Circ Physiol Source Type: research

Managing Chemotherapy-Related Cardiotoxicity in Survivors of Childhood Cancers
Abstract In the US, children diagnosed with cancer are living longer, but not without consequences from the same drugs that cured their cancer. In these patients, cardiovascular disease is the leading cause of non-cancer-related morbidity and mortality. Although this review focuses on anthracycline-related cardiomyopathy in childhood cancer survivors, the global lifetime risk of other cardiovascular diseases such as atherosclerosis, arrhythmias and intracardiac conduction abnormalities, hypertension, and stroke also are increased. Besides anthracyclines, newer molecularly targeted agents, such as vascular endothe...
Source: Pediatric Drugs - October 1, 2014 Category: Pediatrics Source Type: research

The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure
Since the modern era of cancer chemotherapy that began in the mid-1940s, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80% (60). Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk (96). Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease, and valvular disease (96). Their cardiac mortality is 8.2 times higher tha...
Source: AJP: Heart and Circulatory Physiology - November 15, 2014 Category: Cardiology Authors: Lindsey, M. L., Lange, R. A., Parsons, H., Andrews, T., Aune, G. J. Tags: REVIEW Source Type: research

The Great Pot Experiment
Barcott is a journalist who has contributed to the New York Times, National Geographic and other publications. Scherer is TIME’s Washington bureau chief. Portions of this article were adapted from Barcott’s new book “Weed the People, the Future of Legal Marijuana in America,” from TIME Books, is now available wherever books are sold, including Amazon.com, Barnes & Noble and Indiebound. Yasmin Hurd raises rats on the Upper East Side of Manhattan that will blow your mind. Though they look normal, their lives are anything but, and not just because of the pricey real estate they call home on the 10t...
Source: TIME.com: Top Science and Health Stories - May 14, 2015 Category: Consumer Health News Authors: Megan Gibson Tags: Uncategorized Drugs Source Type: news

Children of the 90s more likely to be overweight or obese
Conclusion The study shows how, while the whole population of England has become heavier over the past 70 years, different generations have been affected in different ways. People born in 1946 were, on average, normal weight until their 40s, but this group has since seen their weight rise and they are now, on average, overweight. By the time they reached 60, 75% of men and 66% of women from this group were overweight or obese. People born in 1946 from the heaviest cohorts, who were already overweight in early adulthood, are now likely to be obese or very obese. For people born since 1946, the chance of being overweight a...
Source: NHS News Feed - May 20, 2015 Category: Consumer Health News Tags: Obesity Pregnancy/child Source Type: news

Socio‐Economic Factors Relating to Diabetes and its Management in India
Abstract Diabetes is an escalating problem in India and has major socio‐economic dimensions. Rapid dietary changes coupled with decreased level of physical activity have resulted in increasing obesity and diabetes in rural and semi‐urban areas and in urban based people living in resettlement colonies. Increasing risk has also been recorded in those who suffered from poor childhood nutrition, and in rural‐to‐urban migrants. Social inequity manifests in disparities in socio‐economic strata (SES), place of residence, education, gender, level of awareness and affect prevention, care and management. All these populati...
Source: Journal of Diabetes - May 28, 2015 Category: Endocrinology Authors: Usha Shrivastava, Anoop Misra, Rajeev Gupta, Vijay Viswanathan Tags: Review Article Source Type: research

The Quality Of Health Care You Receive Likely Depends On Your Skin Color
Unequal health care continues to be a serious problem for black Americans. More than a decade after the Institute of Medicine issued a landmark report showing that minority patients were less likely to receive the same quality health care as white patients, racial and ethnic disparities continue to plague the U.S. health care system. That report, which was published in 2002, indicated that even when both groups had similar insurance or the same ability to pay for care, black patients received inferior treatment to white patients. This still hold true, according to our investigation into dozens of studies about black health...
Source: Healthy Living - The Huffington Post - June 29, 2015 Category: Consumer Health News Source Type: news

Health Lunacy and Rocket Science
The failure to use what we have known for more than two decades to prevent up to 80 percent of all major chronic disease -- heart disease, cancer, stroke, diabetes, dementia -- is costing virtually every one of us years lost from lives we love, and life lost from years. Since this is all entirely fixable with knowledge long at our disposal, the calamity of it all is, in a word, lunacy. Of course, in the vernacular, that just means crazy. But the origins of the word point to the moon. And reflections on the moon, as it turns out, could prove... illuminating. There are footprints on the moon for three basic reasons. First,...
Source: Healthy Living - The Huffington Post - July 1, 2015 Category: Consumer Health News Source Type: news

Socioeconomic factors relating to diabetes and its management in India
Abstract Diabetes is an escalating problem in India and has major socioeconomic dimensions. Rapid dietary changes coupled with decreased levels of physical activity have resulted in increases in obesity and diabetes in rural and semi‐urban areas, as well as in urban‐based people living in resettlement colonies. Increasing risk has also been recorded in those who suffered from poor childhood nutrition and in rural‐to‐urban migrants. Social inequity manifests in disparities in socioeconomic status (SES), place of residence, education, gender, and level of awareness and affects prevention, care, and management. All th...
Source: Journal of Diabetes - July 30, 2015 Category: Endocrinology Authors: Usha Shrivastava, Anoop Misra, Rajeev Gupta, Vijay Viswanathan Tags: Review Article Source Type: research

The Southern Diet: Dead on Arrival
We probably could have predicted the outcomes of a recent and well done study. Does a typical Southern diet, rich in fried foods, fatty foods, eggs, processed meats like bacon and ham, organ meats, and sugar rich drinks, promote heart disease? Some clues were available. The yearly map of rates of obesity by state in the U.S. show the Southeast to have the greatest problem with weight. Paula Dean and her cooking led to her declaration that she had diabetes and changes in her recipes. Now researchers from the National Institutes of Health have put the "sugar coating" on the topic by providing strong data condemning this patt...
Source: Healthy Living - The Huffington Post - August 13, 2015 Category: Consumer Health News Source Type: news