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Cancer: Breast Carcinoma
Drug: Taxotere
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Total 81 results found since Jan 2013.
Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma
CONCLUSIONS: We successfully established a highly accurate prognostic model for predicting overall survival and therapeutic effects using TRP channel-related genes.PMID:37733242 | DOI:10.1007/s00432-023-05394-7
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Chong Pang Zhe Xu Jilong Han Fujun Li Hongyan Zhu Jiaqi Zhang Dong Wang Xundi Xu Source Type: research
Impact of adding pertuzumab to trastuzumab plus chemotherapy in neoadjuvant treatment of HER2 positive breast cancer patients: a multicenter real-life HER2PATH study
CONCLUSIONS: This real-life study indicates that adding P to NCT-H enables higher pCR than NCT-H in HER2+ BC, while pCR was associated with lower relapse and better EFS time.PMID:37083566 | DOI:10.1080/0284186X.2023.2202330
Source: Acta Oncologica - April 21, 2023 Category: Cancer & Oncology Authors: Ahmet Bilici Omer Fatih Olmez Muhammed Ali Kaplan Berna Oksuzoglu Ahmet Sezer Nuri Karadurmus Erdem Cubukcu Mehmet Ali Nahit Sendur Sercan Aksoy Dilek Erdem Gul Basaran Burcu Cakar Abdallah T M Shbair Cagatay Arslan Ahmet Taner Sumbul Sema Sezgin Goksu Ib Source Type: research
The prognostic gene CRABP2 affects drug sensitivity by regulating docetaxel-induced apoptosis in breast invasive carcinoma: A pan-cancer analysis
Chem Biol Interact. 2023 Jan 31:110372. doi: 10.1016/j.cbi.2023.110372. Online ahead of print.ABSTRACTCellular retinoic acid-binding protein 2 (CRABP2), a specific transporter of retinoic acid, has been shown to have an important biological role in human cancers. However, due to the substantial variability among different tumors, the role of CRABP2 remains uncertain and has not yet been subjected to systematic analysis. Utilizing The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx), Clinical Proteomic Tumor Analysis Consortium (CPTAC), Human Protein Atlas (HPA), Gene Expression Profiling Interactive Analysis 2...
Source: Chemico-Biological Interactions - February 3, 2023 Category: Molecular Biology Authors: Shuangshuang Zeng Zhijie Xu Qiuju Liang Abhimanyu Thakur Yuanhong Liu Shangjun Zhou Yuanliang Yan Source Type: research
The Decalcification of Cervicothoracic Spinal Metastasis of Breast Cancer Due to Discontinuation of Denosumab: A Case Report
Cureus. 2022 Sep 2;14(9):e28699. doi: 10.7759/cureus.28699. eCollection 2022 Sep.ABSTRACTBreast cancers frequently metastasize to bone. Several guidelines recommend denosumab to control metastasis. In the current case, denosumab allowed the calcification of cervicothoracic spinal metastases following bone decalcification by breast cancer. Six years after administration, denosumab was discontinued and the metastatic lesions became decalcified, but recalcification occurred after re-administration of denosumab. There were no reports of serious decalcification after discontinuation of denosumab. The patient was a 71-year-old w...
Source: Cancer Control - October 7, 2022 Category: Cancer & Oncology Authors: Masaki Tatsumura Takeshi Saito Hiroyuki Ito Kousei Miura Masashi Yamazaki Source Type: research
Emerging role of LINC00461 in cancer
This article summarizes the diagnostic, prognostic, and therapeutic value of LINC00461 in various tumors, and systematically describes the ceRNA network and signaling pathways associated with LINC00461, providing potential directions for future LINC00461 research.PMID:35679722 | DOI:10.1016/j.biopha.2022.113239
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 9, 2022 Category: Drugs & Pharmacology Authors: Qiudan Zhang Chenming Zhong Jinze Shen Sang Chen Yunhua Jia Shiwei Duan Source Type: research
miR-1205/DNAJB1 reverses docetaxel chemoresistance in human triple negative breast carcinoma cells via regulation of mutp53/TAp63 signaling
In this study, we aimed to investigate the molecular mechanism behind DOC chemoresistance and the possible therapeutic effects of miRNAs. Utilizing qRT-PCR analysis, we discovered that miR-1205 is gradually downregulated in human triple negative breast carcinoma MDA-MB-231 and docetaxel-resistant MDA-MB-231 (MDA-MB-231/DOC) cells compared with Hs 578Bst normal human breast fibroblasts. Cell viability, cell cycle and apoptosis assays in MDA-MB-231/DOC cells indicated that miR-1205 overexpression enhances docetaxel sensitivity by reducing cell viability as well as inducing G2/M cell cycle arrest and cell apoptosis. Western b...
Source: Acta Biochimica et Biophysica Sinica - February 7, 2022 Category: Biochemistry Authors: Yongxiang Yin Jinqiu Zhang Tao Ma Daozhen Chen Daru Lu Source Type: research
