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Total 85 results found since Jan 2013.

Hypothermia treatment reduced cyclin-dependent kinase 5-mediated inflammation in ischemic stroke and improved outcomes in ischemic stroke patients
The coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread exponentially worldwide. In Brazil, the number of infected people diagnosed has been increasing and, as in other countries, it has been associated with a high risk of contamination in healthcare teams. For healthcare professionals, the full use of personal protective equipment (PPE) is mandatory, such as wearing surgical or filtering facepiece class 2 (FFP2) masks, waterproof aprons, gloves, and goggles, in addition to training in care processes. A reduction in the number of face-to-face visits an...
Source: Clinics - July 11, 2020 Category: General Medicine Source Type: research

Learning non-local perfusion textures for high-quality computed tomography perfusion imaging
CONCLUSIONS: The presented NPTN method can obtain high-quality CTP images and estimate high-accuracy CBF map by characterizing more structure details and contrast variants in the CTP image, and outperform the competing methods at low-dose cases.PMID:33910178 | DOI:10.1088/1361-6560/abfc90
Source: Physics in Medicine and Biology - April 28, 2021 Category: Physics Authors: Sui Li Dong Zeng Zhaoying Bian Danyang Li Manman Zhu Jing Huang Jianhua Ma Source Type: research

Diagnostic reference levels and median doses for common clinical indications of CT: findings from an international registry
ConclusionsDRLs for CTDIvol and DLP for EUCLID clinical indications from diverse organizations were established and can contribute to dose optimization. These values were usually significantly higher in the US than in Europe.Key Points•Registry data were used to create benchmarks for 10 common indications for CT identified by the European Society of Radiology.•Observed US radiation doses were higher than European for 9 of 10 indications (except chronic sinusitis).•The presented diagnostic reference levels and median doses highlight potentially unnecessary variation in radiation dose.
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Hypoxanthine is a pharmacodynamic marker of ischemic brain edema modified by glibenclamide
Cell Rep Med. 2022 Jun 9:100654. doi: 10.1016/j.xcrm.2022.100654. Online ahead of print.ABSTRACTBrain edema after a large stroke causes significant morbidity and mortality. Here, we seek to identify pharmacodynamic markers of edema that are modified by intravenous (i.v.) glibenclamide (glyburide; BIIB093) treatment. Using metabolomic profiling of 399 plasma samples from patients enrolled in the phase 2 Glyburide Advantage in Malignant Edema and Stroke (GAMES)-RP trial, 152 analytes are measured using liquid chromatography-tandem mass spectrometry. Associations with midline shift (MLS) and the matrix metalloproteinase-9 (MM...
Source: Cancer Control - June 14, 2022 Category: Cancer & Oncology Authors: Hannah J Irvine Animesh Acharjee Zoe Wolcott Zsuzsanna Ament H E Hinson Bradley J Molyneaux J Marc Simard Kevin N Sheth W Taylor Kimberly Source Type: research

How AI Is Changing Medical Imaging to Improve Patient Care
That doctors can peer into the human body without making a single incision once seemed like a miraculous concept. But medical imaging in radiology has come a long way, and the latest artificial intelligence (AI)-driven techniques are going much further: exploiting the massive computing abilities of AI and machine learning to mine body scans for differences that even the human eye can miss. Imaging in medicine now involves sophisticated ways of analyzing every data point to distinguish disease from health and signal from noise. If the first few decades of radiology were about refining the resolution of the pictures taken of...
Source: TIME: Health - November 4, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Frontiers of Medicine 2022 healthscienceclimate Innovation sponsorshipblock Source Type: news

GMC invests $1.7M in 128-slice CT scanner
Gwinnett Medical Center has invested $1.7 million in a computed tomography (CT) scanner at its Lawrenceville hospital. The 128-slice CT scanner will be used in GMC Lawrenceville's emergency room, which is a Level II trauma center. The CT scanner boasts lower radiation levels than conventional x-ray devices, and allows physicians to see what was previously unseen, a hospital spokeswoman noted. The device will be used for bariatric, cancer, stroke and cardiac patients because it offers 4-D imaging,…
Source: bizjournals.com Health Care:Biotechnology headlines - January 4, 2013 Category: Biotechnology Authors: Urvaksh Karkaria Source Type: research

157 E-Books New to JEFFLINE
Scott Library added these 157 e-books to the growing collection in May and June: Accurate Results in the Clinical Laboratory Adult Emergency Medicine Adult-Gerontology and Family Nurse Practitioner Certification Examination (4th ed.) Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses (2nd ed.) Advancing Your Career: Concepts of Professional Nursing (5th ed.) Arrhythmia Essentials Atlas of Advanced Operative Surgery Atlas of Clinical Neurology (3rd ed.) Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Atlas of Human Infectious Diseases Atlas of No...
Source: What's New on JEFFLINE - June 25, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Multiple Ischemic Strokes Caused by Nonbacterial Thrombotic Endocarditis Because of Gallbladder Cancer: A Case Report
We report a case of a 62-year-old woman with multiple ischemic strokes caused by nonbacterial thrombotic endocarditis (NBTE) because of gallbladder cancer. Transesophageal echocardiography showed NBTE on the mitral valve. The NBTE disappeared with anticoagulation treatment for 2 weeks. Abdominal computed tomography showed a gallbladder tumor that was surgically resected. Histopathologic studies showed poorly differentiated tumor cells and the production of mucin. Trousseau syndrome with gallbladder cancer is very rare. We suggest that the development of NBTE is related to the production of mucin.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2014 Category: Neurology Authors: Akiko Yamane, Hirokazu Sadahiro, Hisaharu Goto, Akinori Inamura, Hideyuki Ishihara, Fumiaki Oka, Takayuki Oku, Tomoko Kondo, Michiyasu Suzuki Tags: Case Reports Source Type: research

Lung cancer screening with low-dose CT (LDCT) is ready for prime time in the USA
Commentary on: Humphrey LL, Deffebach M, Pappas M, et al.. Screening for lung cancer with low-dose computed tomography: a systematic review to update the US Preventive Services Task Force recommendation. Ann Intern Med 2013;159:411–20. Context The US Preventative Services Task Force (USPSTF) has published their long-awaited, updated systematic review of low-dose CT (LDCT) screening for lung cancer. Last reviewed in 2004, lung cancer screening has been under intense study worldwide for the past decade. The issue of lung cancer screening is important because lung cancer is the leading cause of cancer mortality in the U...
Source: Evidence-Based Medicine - July 18, 2014 Category: Internal Medicine Authors: Wilson, D. O. Tags: Smoking and tobacco, Health policy, Clinical trials (epidemiology), Epidemiologic studies, Immunology (including allergy), Stroke, Screening (oncology), Radiology, Clinical diagnostic tests, Radiology (diagnostics), Screening (epidemiology), Health econom Source Type: research

Cut CT radiation dose say experts
Radiation safety committee reports that record numbers of CT scans were carried out last year Related items from OnMedicaWorried-well health 'MoTs' banned due to cancer riskPatients’ exposure to X-ray radiation fallingMRI in breast cancer fails to cut reoperation rateNew imaging method uses sugar to show-up tumorsRadiation exposure may increase risk of stroke and heart disease
Source: OnMedica Latest News - August 15, 2014 Category: UK Health Source Type: news

Caution urged over CT scan radiation doses
BBC News reports on a sharp rise in the number of CT scans being performed, exposing people to the potential health risks of radiation. However, as The Daily Telegraph says, it is not possible to calculate the cancer risk due to exposure to CT scans because there is a lack of data. These media stories follow the publication of a report by the Committee on Medical Aspects of Radiation in the Environment (COMARE). COMARE has reviewed trends in the use of CT scans in the UK. The review weighs up the risk-benefit balance of using CT scans, and considers ways to obtain the best quality scan image while minimising the necessary...
Source: NHS News Feed - August 15, 2014 Category: Consumer Health News Tags: Medical practice Source Type: news

A potential role of ECG-Gated CT for the diagnosis of pulmonary vein thrombus; an illustrative case report
The presence of tumor thrombus in patients with lung cancer confers a risk of stroke and other end organ ischemic events. This case highlights a potential role for ECG-Gated Computed Tomography (ECG-CT) in the diagnosis of this pathologic process. In this case pulmonary vein thrombus was definitively identified by an ECG-CT following discordant results between Computed Tomography (CT) and Transthoracic Echocardiogram (TTE). In addition, this case demonstrates how management decisions are affected by physician accessibility to and familiarity with specific imaging tests.
Source: Clinical Imaging - November 21, 2014 Category: Radiology Authors: Michael A. Winkler, Paul von Herrmann, Ryan H. Penticuff, Palak M. Majmudar, Benjamin R. Plaisance, Stephen B. Hobbs Tags: Case Report Source Type: research

Radiation protection issues in dynamic contrast-enhanced (perfusion) computed tomography
Publication date: Available online 20 November 2014 Source:European Journal of Radiology Author(s): Gunnar Brix , Ursula Lechel , Elke Nekolla , Jürgen Griebel , Christoph Becker Dynamic-contrast enhanced (DCE) CT studies are increasingly used in both medical care and clinical trials to improve diagnosis and therapy management of the most common life-threatening diseases: stroke, coronary artery disease and cancer. It is thus the aim of this review to briefly summarize the current knowledge on deterministic and stochastic radiation effects relevant for patient protection, to present the essential concepts for determinin...
Source: European Journal of Radiology - November 21, 2014 Category: Radiology Source Type: research