Multiple Ischemic Strokes Caused by Nonbacterial Thrombotic Endocarditis Because of Gallbladder Cancer: A Case Report

We report a case of a 62-year-old woman with multiple ischemic strokes caused by nonbacterial thrombotic endocarditis (NBTE) because of gallbladder cancer. Transesophageal echocardiography showed NBTE on the mitral valve. The NBTE disappeared with anticoagulation treatment for 2 weeks. Abdominal computed tomography showed a gallbladder tumor that was surgically resected. Histopathologic studies showed poorly differentiated tumor cells and the production of mucin. Trousseau syndrome with gallbladder cancer is very rare. We suggest that the development of NBTE is related to the production of mucin.

Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2014 Category: Neurology Authors: Akiko Yamane, Hirokazu Sadahiro, Hisaharu Goto, Akinori Inamura, Hideyuki Ishihara, Fumiaki Oka, Takayuki Oku, Tomoko Kondo, Michiyasu Suzuki Tags: Case Reports Source Type: research