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Total 4394 results found since Jan 2013.

Social Determinants of Health and Racial Disparities in Cardiac Events in Breast Cancer
CONCLUSIONS: Neighborhood and built environment variables are the most important SDOH predictors for 2-year MACE, and NHB patients were more likely to have unfavorable SDOH conditions. This finding reinforces that race is a social construct.PMID:37433439 | DOI:10.6004/jnccn.2023.7023
Source: Journal of the National Comprehensive Cancer Network : JNCCN - July 11, 2023 Category: Cancer & Oncology Authors: Nickolas Stabellini Mantas Dmukauskas Marcio S Bittencourt Jennifer Cullen Amie J Barda Justin X Moore Susan Dent Husam Abdel-Qadir Aniket A Kawatkar Ambarish Pandey John Shanahan Jill S Barnholtz-Sloan Kristin A Waite Alberto J Montero Avirup Guha Source Type: research

Chlorthalidone versus hydrochlorothiazide for preventing cardiovascular disease in hypertension: Is the case closed?
Hellenic J Cardiol. 2023 Jul 8:S1109-9666(23)00115-X. doi: 10.1016/j.hjc.2023.07.003. Online ahead of print.ABSTRACTThe optimal diuretic choice [hydrochlorothiazide (HCTZ) or chlorthalidone (CTD)] for the management of hypertension has been an ongoing debate for several years. HCTZ is widely used in the form of single-pill combinations, whereas CTD is a more potent drug vs. HCTZ, especially in reducing nighttime blood pressure (BP), with some indirect evidence suggesting a superiority in terms of cardiovascular (CV) risk reduction. In addition, recent data showed that CTD was safe and effective in terms of BP lowering in p...
Source: Hellenic Journal of Cardiology - July 10, 2023 Category: Cardiology Authors: Anastasios Kollias Konstantinos G Kyriakoulis George S Stergiou Source Type: research

The effect of intraoperative goal-directed fluid therapy combined with enhanced recovery after surgery program on postoperative complications in elderly patients undergoing thoracoscopic pulmonary resection: a prospective randomized controlled study
ConclusionsUnder ERAS program, there was no significant difference of AKI incidence between GDFT and RFT in elderly patients undergoing thoracoscopic pulmonary resection. But postoperative increase degree of serum creatinine was lower in GDFT group.Trial registrationRegistered at ClinicalTrials.gov, NCT04302467 on 26 February 2020.
Source: Perioperative Medicine - July 10, 2023 Category: Surgery Source Type: research

Nanoparticle-mediated delivery of microRNAs-based therapies for treatment of disorders
Pathol Res Pract. 2023 Jul 3;248:154667. doi: 10.1016/j.prp.2023.154667. Online ahead of print.ABSTRACTmiRNAs represent appropriate candidates for treatment of several disorders. However, safe and efficient delivery of these small-sized transcripts has been challenging. Nanoparticle-based delivery of miRNAs has been used for treatment of a variety of disorders, particularly cancers as well as ischemic stroke and pulmonary fibrosis. The wide range application of this type of therapy is based on the important roles of miRNAs in the regulation of cell behavior in physiological and pathological conditions. Besides, the ability...
Source: Pathology, Research and Practice - July 9, 2023 Category: Pathology Authors: Soudeh Ghafouri-Fard Hamed Shoorei Leili Noferesti Bashdar Mahmud Hussen Mohammad Hossein Behzad Moghadam Mohammad Taheri Fariborz Rashnoo Source Type: research

Risk of arterial thromboembolism, bleeding and mortality in atrial fibrillation patients with comorbid cancer: a systematic review and meta-analysis
CONCLUSION: In AF patients, the presence of cancer is associated with a similar risk of TE and an increased risk of bleeding and all-cause death.PMID:37414144 | DOI:10.1016/j.hjc.2023.06.005
Source: Hellenic Journal of Cardiology - July 6, 2023 Category: Cardiology Authors: Charalampos Balomenakis Andreas S Papazoglou Dimitra Vlachopoulou Anastasios Kartas Dimitrios V Moysidis Ioannis Vouloagkas Christos Tsagkaris Konstantinos Georgopoulos Athanasios Samaras Efstratios Karagiannidis George Giannakoulas Source Type: research

Cancers, Vol. 15, Pages 3503: The Risk of Ischemic and Hemorrhagic Stroke in Head and Neck Cancer: A Longitudinal Cohort Study
u Kim Several studies have shown that head and neck cancer is associated with an increased risk of stroke incidence. However, investigations of the association between the two diseases based on a matching cohort dataset are still limited. Therefore, we identified the incidence and risk of stroke in patients with head and neck cancer using a nationwide population-based cohort dataset. A total of 5248 individuals without cancer and 1312 with cancer were enrolled from the dataset after a 4:1 propensity score matching. We found that the incidence of overall stroke (per 1000 person years) was 19.29 for those with head and n...
Source: Cancers - July 5, 2023 Category: Cancer & Oncology Authors: Chulho Kim Hyunjae Yu Dong-Kyu Kim Tags: Article Source Type: research

Estimating the Cost of Delivering Tobacco Cessation Intervention Package at Non-Communicable Disease Clinics in Two Districts of North India
CONCLUSION: The development costs of the intervention package accounted for the majority proportion of the total cost. Of the total unit cost of implementation, the telephonic follow-up, human resources, and capital resources were the major contributory components.IMPLICATIONS: The current study aims to fill gaps by estimating the unit-level health systems cost of a culturally sensitive, disease-specific, and patient-centric tobacco cessation intervention package delivered at the outpatient settings of NCD clinics at the secondary level hospital, which represents a major link in the health care system of India. Findings fr...
Source: Cancer Control - July 4, 2023 Category: Cancer & Oncology Authors: Garima Bhatt Sonu Goel Tanvi Kira Sandeep Grover Bikash Medhi Gurmandeep Singh Sandeep Singh Gill Source Type: research

A Comparative Study of Ultrasmall Calcium Carbonate Nanoparticles for Targeting and Imaging Atherosclerotic Plaque
ACS Nano. 2023 Jul 3. doi: 10.1021/acsnano.3c03523. Online ahead of print.ABSTRACTAtherosclerosis is a complex disease that can lead to life-threatening events, such as myocardial infarction and ischemic stroke. Despite the severity of this disease, diagnosing plaque vulnerability remains challenging due to the lack of effective diagnostic tools. Conventional diagnostic protocols lack specificity and fail to predict the type of atherosclerotic lesion and the risk of plaque rupture. To address this issue, technologies are emerging, such as noninvasive medical imaging of atherosclerotic plaque with customized nanotechnologic...
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: Lydia Mart ínez-Parra Marina Pi ñol-Cancer Carlos Sanchez-Cano Ana B Miguel-Coello Desir è Di Silvio Ana M Gomez Clara Uriel Sandra Plaza-Garc ía Marta Gallego Raquel Pazos Hugo Groult Marc Jeannin Kalotina Geraki Laura Fern ández-Méndez Ainhize Urk Source Type: research