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Total 5013 results found since Jan 2013.

Surrogate Adiposity Markers and Mortality
CONCLUSIONS AND RELEVANCE: In this cohort study, WHR had the strongest and most consistent association with mortality irrespective of BMI. Clinical recommendations should consider focusing on adiposity distribution compared with mass.PMID:37728925 | DOI:10.1001/jamanetworkopen.2023.34836
Source: Atherosclerosis - September 20, 2023 Category: Cardiology Authors: Irfan Khan Michael Chong Ann Le Pedrum Mohammadi-Shemirani Robert Morton Christina Brinza Michel Kiflen Sukrit Narula Loubna Akhabir Shihong Mao Katherine Morrison Marie Pigeyre Guillaume Par é Source Type: research

Multi-Cancer Early Detection: The New Frontier in Cancer Early Detection
Annu Rev Med. 2023 Sep 20. doi: 10.1146/annurev-med-050522-033624. Online ahead of print.ABSTRACTThe new generation of cancer early detection tests holds remarkable promise for revolutionizing and changing the paradigm of cancer early detection. Dozens of cancer early detection tests are being developed and evaluated. Some are already commercialized and available for use, most as a complement to and not in place of existing recommended cancer screening tests. This review evaluates existing single- and multi-cancer early detection tests (MCEDs), discussing their performance characteristics including sensitivity, specificity...
Source: Annual Review of Medicine - September 20, 2023 Category: General Medicine Authors: Carmen E Guerra Prateek V Sharma Brenda S Castillo Source Type: research

The quality and clinical translation of radiomics studies based on MRI for predicting Ki-67 levels in patients with breast cancer
CONCLUSION: Ki-67 index is a common tumor biomarker with high clinical value. Radiomics is an ever-growing quantitative data-mining method helping predict tumor biomarkers from medical images. However, the quality of the reviewed studies evaluated by the RQS was not so satisfactory and there are ample opportunities for improvement. Open science and data, external validation, phantom study, publicly open radiomics database and standardization in the radiomics practice are what researchers should pay more attention to in the future.ADVANCES IN KNOWLEDGE: The RQS tool considered the radiomics used to predict the Ki-67 level w...
Source: The British Journal of Radiology - September 19, 2023 Category: Radiology Authors: Min Wang Ting Mei Youling Gong Source Type: research

Ranitidine Use and Incident Cancer in a Multinational Cohort
CONCLUSIONS AND RELEVANCE: In this cohort study, ranitidine use was not associated with an increased risk of cancer compared with the use of other H2RAs. Further research is needed on the long-term association of ranitidine with cancer development.PMID:37725377 | DOI:10.1001/jamanetworkopen.2023.33495
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Seng Chan You Seung In Seo Thomas Falconer Chen Yanover Talita Duarte-Salles Sarah Seager Jose D Posada Nigam H Shah Phung-Anh Nguyen Yeesuk Kim Jason C Hsu Mui Van Zandt Min-Huei Hsu Hang Lak Lee Heejoo Ko Woon Geon Shin Nicole Pratt Rae Woong Park Chris Source Type: research

Neoadjuvant chemotherapy for advanced colonic cancer: standard of care or is the jury still out?
Br J Surg. 2023 Sep 19:znad281. doi: 10.1093/bjs/znad281. Online ahead of print.NO ABSTRACTPMID:37724780 | DOI:10.1093/bjs/znad281
Source: The British Journal of Surgery - September 19, 2023 Category: Surgery Authors: Peter G Vaughan-Shaw Martyn D Evans Source Type: research

The quality and clinical translation of radiomics studies based on MRI for predicting Ki-67 levels in patients with breast cancer
CONCLUSION: Ki-67 index is a common tumor biomarker with high clinical value. Radiomics is an ever-growing quantitative data-mining method helping predict tumor biomarkers from medical images. However, the quality of the reviewed studies evaluated by the RQS was not so satisfactory and there are ample opportunities for improvement. Open science and data, external validation, phantom study, publicly open radiomics database and standardization in the radiomics practice are what researchers should pay more attention to in the future.ADVANCES IN KNOWLEDGE: The RQS tool considered the radiomics used to predict the Ki-67 level w...
Source: The British Journal of Radiology - September 19, 2023 Category: Radiology Authors: Min Wang Ting Mei Youling Gong Source Type: research

Angiosarcoma in the breast: a population-based cohort from Sweden
CONCLUSION: Breast angiosarcoma is a rare disease strongly associated with a history of previous BC RT. Overall survival is poor with high rates of local recurrences and distant metastasis.PMID:37708086 | DOI:10.1093/bjs/znad290
Source: The British Journal of Surgery - September 14, 2023 Category: Surgery Authors: Susanne Olander Anna-Karin Wennstig Hans Garmo Lars Holmberg Greger Nilsson Carl Blomqvist Fredrik Karlsson Åsa Wickberg Fredrik W ärnberg Malin Sund Charlotta Wadsten Source Type: research

Successes and challenges in extracting information from DICOM image databases for audit and research
Br J Radiol. 2023 Sep 12:20230104. doi: 10.1259/bjr.20230104. Online ahead of print.ABSTRACTIn radiography, much valuable associated data (metadata) is generated during image acquisition. The current setup of picture archive and communication systems (PACS) can make extraction of this metadata difficult, especially as it is typically stored with the image. The aim of this work is to examine the current challenges in extracting image metadata and to discuss the potential benefits of using this rich information. This work focuses on breast screening, though the conclusions are applicable to other modalities.The data stored i...
Source: The British Journal of Radiology - September 12, 2023 Category: Radiology Authors: Alistair Mackenzie Emma Lewis John Loveland Source Type: research

Carotenoid dietary intakes and plasma concentrations are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort - CORRIGENDUM
Br J Nutr. 2023 Sep 11:1. doi: 10.1017/S0007114523002003. Online ahead of print.NO ABSTRACTPMID:37694519 | DOI:10.1017/S0007114523002003
Source: The British Journal of Nutrition - September 11, 2023 Category: Nutrition Authors: Richard Hayhoe Marleen Lentjes Angela Mulligan Robert Luben Kay-Tee Khaw Ailsa Welch Source Type: research

Replacing red and processed meat with lean or fatty fish and all-cause and cause specific mortality in Norwegian women. The Norwegian Women and Cancer Study (NOWAC): a prospective cohort study
This study investigated the replacement of red and processed meat with fish in relation to mortality. Of 83 304 women in the NOWAC Study, 9 420 died during a median of 21.0 years of follow-up. The hazard ratios (HRs) for mortality were estimated using Cox Proportional Hazards regression with analyses stratified on red and processed meat intake due to non-linearity. Higher processed meat (>30 grams/day), red and processed meat (>50 grams/day), and fatty fish consumption were associated with higher mortality, while red meat and lean fish consumption were neutral or beneficial. Among women with higher processed meat int...
Source: The British Journal of Nutrition - September 11, 2023 Category: Nutrition Authors: Torill M Enget Jensen Tonje Braaten Bjarne K Jacobsen Daniel B Ibsen Guri Skeie Source Type: research

Endoscopic Surgical Skill Qualification System: propensity-score matched cohort analysis of accredited supervisors in laparoscopic rectal cancer surgery
CONCLUSION: This study demonstrated the educational benefits of ESSQS-certified supervisors, including assistants and advisors, evidenced by their superior short-term outcomes.PMID:37695301 | DOI:10.1093/bjs/znad282
Source: The British Journal of Surgery - September 11, 2023 Category: Surgery Authors: Yuki Kiyozumi Tomohiro Yamaguchi Nobuki Ichikawa Shigenori Homma Koji Ikeda Ryo Inada Koki Otsuka Akinobu Furutani Hiroaki Iijima Masahiko Watanabe Akinobu Taketomi Takeshi Naitoh EnSSURE study group collaborators in the Japan Society of Laparoscopic Colo Source Type: research