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Total 1762 results found since Jan 2013.

Is cervical dysplasia a major concern in women with inflammatory bowel disease? A Spanish retrospective study
Rev Esp Enferm Dig. 2023 Sep 21. doi: 10.17235/reed.2023.9890/2023. Online ahead of print.ABSTRACTCervical cancer (CC) is the fourth most common cancer affecting women worldwide. The risk of women immunosuppressed due to AIDS or organ transplantation is well documented, as most cases are caused by persistent human papillomavirus (HPV) infection and immunosuppression can prevent clearing HPV. Although European guidelines advise that inflammatory bowel disease (IBD) women under immunosuppression should be screened for CC as regularly as high-risk patients, quality evidence is lacking in our country. We performed a retrospect...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Lorena Jara Fern ández Juan Ángel Ferrer Jos é Lázaro Pérez Calle Pilar L ópez Serrano Source Type: research

Chronic Respiratory Diseases as a Risk Factor for Herpes Zoster Infection
CONCLUSIONS: In a standard clinical practice setting, the most prevalent respiratory diseases (asthma, COPD and lung cancer) are related to a higher risk of HZ and PHN. These data are fundamental to assess the potential impact of vaccination in this population.PMID:37734964 | DOI:10.1016/j.arbres.2023.08.010
Source: Archivos de Bronconeumologia - September 21, 2023 Category: Respiratory Medicine Authors: Diego Morena Sara Lumbreras Jos é Miguel Rodríguez Carolina Campos Mar ía Castillo Mar ía Benavent Jos é Luis Izquierdo Source Type: research

Patients experience of using colonoscopy as a diagnostic test after a positive FOBT/FIT: a systematic review of the quantitative literature
Conclusion This review highlighted that patient-reported experiences associated with colonoscopy were generally positive. To improve the colonoscopy experience, bowel screening centres should investigate means to: make bowel preparation more acceptable, make colonoscopy less painful and reduce post-colonoscopy symptoms.
Source: BMJ Open - September 21, 2023 Category: General Medicine Authors: Kayal, G., Kerrison, R., Hirst, Y., von Wagner, C. Tags: Open access, Public health Source Type: research

Lifetime exposure to brominated trihalomethanes in drinking water and swimming pool attendance are associated with chronic lymphocytic leukemia: a Multicase-Control Study in Spain (MCC-Spain)
This study identifies an association of long-term exposure to THMs in drinking water, at concentrations below the regulatory thresholds and WHO guidelines, and swimming pool attendance, with chronic lymphocytic leukemia (CLL). These unprecedented findings are highly relevant since CLL is an incurable cancer with still unknown etiology and because the widespread exposure to chlorination by-products that remain in drinking and recreational water worldwide. Despite the demonstrated carcinogenicity in animals of several chlorination by-products, little is known about their potential risks on human health. This study makes a si...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Carolina Donat-Vargas Manolis Kogevinas Yolanda Benavente Laura Costas Elias Campo Gemma Casta ño-Vinyals Guillermo Fernandez-Tardon Javier Llorca In és Gómez-Acebo Nuria Aragon és Marina Pollan Delphine Casabonne Cristina M Villanueva Source Type: research

Ranitidine Use and Incident Cancer in a Multinational Cohort
CONCLUSIONS AND RELEVANCE: In this cohort study, ranitidine use was not associated with an increased risk of cancer compared with the use of other H2RAs. Further research is needed on the long-term association of ranitidine with cancer development.PMID:37725377 | DOI:10.1001/jamanetworkopen.2023.33495
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Seng Chan You Seung In Seo Thomas Falconer Chen Yanover Talita Duarte-Salles Sarah Seager Jose D Posada Nigam H Shah Phung-Anh Nguyen Yeesuk Kim Jason C Hsu Mui Van Zandt Min-Huei Hsu Hang Lak Lee Heejoo Ko Woon Geon Shin Nicole Pratt Rae Woong Park Chris Source Type: research

Cost-Effectiveness of Lorlatinib for the Treatment of Adult Patients with Anaplastic Lymphoma Kinase Positive Advanced Non-Small Cell Lung Cancer in Spain
CONCLUSION: The results of this study suggest that lorlatinib may be a dominant treatment option versus alectinib. Considering a willingness-to-pay threshold of €25,000/QALY, lorlatinib may be an efficient option compared to brigatinib.PMID:37701861 | PMC:PMC10494862 | DOI:10.2147/CEOR.S415711
Source: Cell Research - September 13, 2023 Category: Cytology Authors: Mar ía Presa David Vicente Antonio Calles Laura Salinas-Ortega Jaesh Naik Luis F Garc ía Javier Soto Source Type: research

Risk of endometrial cancer after RRSO in BRCA 1/2 carriers: a multicentre cohort study
CONCLUSIONS: In our cohort, the risk of EC in BRCA1/2 carriers after RRSO is not greater than expected. Hysterectomy is not routinely recommended for these patients.PMID:37682500 | DOI:10.1007/s12094-023-03312-4
Source: Clinical Breast Cancer - September 8, 2023 Category: Cancer & Oncology Authors: Helena Pla-Juher Marta Pardo Àngel J Izquierdo Esther Darder Anna Carb ó Elisabet Munt é Sara Torres-Esquius Judith Balma ña Concepci ón Lázaro Joan M Brunet Maria-Pilar Barretina-Ginesta Source Type: research

Disparities in Clinical Trial Enrollment and Reporting in Rectal Cancer: A Systematic Review and Demographic Comparison to the National Cancer Database
CONCLUSION: The present study supports the need for improved demographic representation and transparency in rectal cancer clinical trials.PMID:37670471 | DOI:10.1177/00031348231191175
Source: The American Surgeon - September 6, 2023 Category: Surgery Authors: Tuleen Sawaf Rachana Gudipudi Asya Ofshteyn Anuja L Sarode Katherine Bingmer Jonathan Bliggenstorfer Sharon L Stein Emily Steinhagen UH-RISES (University Hospitals Research in Surgical Outcomes and Effectiveness Center) Source Type: research

Difficulties on the access to innovative targeted therapies for lung cancer in Spain
CONCLUSION: SLCG considers imperative to improve the access in Spain to innovative treatments for NSCLC to reduce inequity across European countries.PMID:37651020 | DOI:10.1007/s12094-023-03303-5
Source: Clinical Lung Cancer - August 31, 2023 Category: Cancer & Oncology Authors: Virginia Calvo Carlos Camps Enric Carcereny Manuel Cobo Manuel D ómine Mar ía Rosario García Campelo Jos é Luis González Larriba Mar ía Guirado Florentino Hernando-Trancho Bartomeu Massut í Ernest Nadal Delvys Rodr íguez-Abreu Alfredo S ánchez Iv Source Type: research

A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer
CONCLUSIONS: We found that ABCA2 polymorphism was significantly associated with systemic exposure to capecitabine and capecitabine-induced neutropenia in Japanese patients with CRC.PMID:37653272 | DOI:10.1007/s00280-023-04584-x
Source: Clinical Colorectal Cancer - August 31, 2023 Category: Cancer & Oncology Authors: Yukitaka Shibata Natsumi Matsumoto Remi Murase Yutaro Kubota Hiroo Ishida Ken Shimada Ken-Ichi Fujita Source Type: research

Real-world study on microsatellite instability and mismatch repair deficiency testing patterns among patients with metastatic colorectal cancer in Spain
CONCLUSION: Our study suggests that a high proportion of patients with mCRC are currently tested for dMMR/MSI-H in tertiary hospitals across Spain. However, there is still room for improvement until universal testing is achieved.TRIAL REGISTRATION: Not applicable.PMID:37651021 | DOI:10.1007/s12094-023-03309-z
Source: Clinical Colorectal Cancer - August 31, 2023 Category: Cancer & Oncology Authors: Rocio Garcia-Carbonero Beatriz Gonz ález Astorga Rosario Vidal Tocino D ébora Contreras Toledo Carles Pericay Ana Fern ández Montes Esther Falc ó Marta Gonz ález Cordero Juan Jos é Reina Zoilo Vicente Alonso Nuria Rodr íguez Salas Mireia Gil-Raga C Source Type: research