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Be Prepared For The Next Pandemic
Whether pro-vaccine or anti-vaccine, you’re not getting the complete Covid picture. That’s why it’s so important that you take steps to protect yourself. When it comes to this virus, the truth is a moving target. This is partly because the virus is evolving but mostly because we just don’t have the data we need to make a truly informed decision. And here’s one narrative no one is talking about… Studies show that chemicals commonly found in food and consumer products weaken your immune system and make the symptoms of Covid worse — especially among those who are already vulnerable.1 You see, these toxins in...
Source: Al Sears, MD Natural Remedies - December 23, 2022 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Anti-inflammatory and anti-allergic potential of dietary flavonoids: A review
Biomed Pharmacother. 2022 Dec;156:113945. doi: 10.1016/j.biopha.2022.113945. Epub 2022 Oct 31.ABSTRACTChronic inflammation plays an imperative role in the onset and progression of chronic diseases including diabetes, hypertension, cancer, allergies, and asthma. Diet can modulate different stages of inflammation since it is a rich source of antioxidants and bioactive compounds. Flavonoids are bioactive compounds abundantly found in various food groups such as vegetables, fruits, nuts, cereals, and beverages. Recent work on flavonoids has unveiled their potential to regulate or inhibit inflammation. This is attributed to the...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 22, 2022 Category: Drugs & Pharmacology Authors: Allah Rakha Nehal Umar Roshina Rabail Masood Sadiq Butt Marek Kieliszek Abdo Hassoun Rana Muhammad Aadil Source Type: research

Why Mark Cuban Is Selling Anti-Fungal Ointment for $7.34
Mark Cuban, the tech titan, Dallas Mavericks owner, and star of ABC’s Shark Tank, moves through the world like a friendly great white, all teeth and eyes and relentless motion. When we meet on an October morning at his office in the Mavericks’ headquarters, the serial entrepreneur, 64, is wearing a long-sleeved T-shirt advertising his last investment: Mark Cuban Cost Plus Drug Co. I was there to find out why a guy who’s made billions in tech, won an NBA championship, and become perhaps the most popular businessman on reality TV was spending his time and fortune hawking generic anti-fungal medications onli...
Source: TIME: Health - November 17, 2022 Category: Consumer Health News Authors: Charlotte Alter/Dallas Tags: Uncategorized Health Care Magazine uspoliticspolicy Source Type: news

Anticancer effects of Poncirus  fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion.
This study investigated the ability of PF to induce apoptosis and inhibit the invasiveness and migratory ability of HCC cell lines (Hep3B and Huh7). Wound healing, Transwell migration and invasion, and colony‑formation assays, as well as flow cytometry, were used to analyze cell proliferation, migration, invasion, and apoptosis. Epithelial‑mesenchymal transition (EMT)‑related and apoptotic proteins were assessed by western blotting. The mitochondrial membrane potential of the Hep3B and Huh7 cells was observed with tetramethylrhodamine ethyl ester. The reactive oxygen species (ROS) level was determined by dihydroethid...
Source: Oncology Reports - November 1, 2020 Category: Cancer & Oncology Tags: Oncol Rep Source Type: research

Naringenin Suppresses Chemically Induced Skin Cancer in Two-Stage Skin Carcinogenesis Mouse Model.
Conclusion: Naringenin exhibited anti-tumor effect in two stage carcinogenesis mouse skin tumor model. This study revealed that consumption of citrus fruits and the naringenin therein may be helpful in suppression of skin cancer. PMID: 31474152 [PubMed - as supplied by publisher]
Source: Nutrition and Cancer - September 1, 2019 Category: Cancer & Oncology Authors: Kumar R, Bhan Tiku A Tags: Nutr Cancer Source Type: research

Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives
Joseph D. Romano1,2,3,4 and Nicholas P. Tatonetti1,2,3,4* 1Department of Biomedical Informatics, Columbia University, New York, NY, United States 2Department of Systems Biology, Columbia University, New York, NY, United States 3Department of Medicine, Columbia University, New York, NY, United States 4Data Science Institute, Columbia University, New York, NY, United States The discovery of new pharmaceutical drugs is one of the preeminent tasks—scientifically, economically, and socially—in biomedical research. Advances in informatics and computational biology have increased productivity at many ...
Source: Frontiers in Genetics - April 29, 2019 Category: Genetics & Stem Cells Source Type: research

Here ’s Everything You Need to Know About Gut Health
It’s hardly news that the gastrointestinal tract is important to human health: It transports food from the mouth to the stomach, converts it into absorbable nutrients and stored energy, and shuttles waste back out of the body. If you don’t properly nourish yourself, you don’t live. It’s that simple. But in recent years, scientists have discovered that the GI system has an even bigger, more complex job than previously appreciated. It’s been linked to numerous aspects of health that have seemingly nothing to do with digestion, from immunity to emotional stress to chronic illnesses, including can...
Source: TIME: Health - March 25, 2019 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized Research Source Type: news

6,000-year-old track record for healing leaky gut
When I was traveling in India, I had the privilege of studying Ayurvedic medicine with traditional Master Healers. Surrounded by lakes, oceans and mountains, Kerala, India, is the birthplace of Ayurveda medicine. My plane landed in Mumbai. From there, I made the 800-mile trip to Kerala down on the southwestern-most tip of the Indian peninsula. With origins dating back 6,000 years, Kerala is the birthplace of Ayurvedic medicine. I spent a lot of time at the AyurMana or “ancient healing house.” This is the oldest existing school of Ayurvedic medicine in the world. It was there that I observed how quickly Ayurved...
Source: Al Sears, MD Natural Remedies - January 17, 2018 Category: Complementary Medicine Authors: Cathy Card Tags: Health Natural Cures anxiety arthritis Cancer celiac disease chronic fatigue depression diabetes digestive issues fibromyalgia leaky gut multiple sclerosis schizophrenia Source Type: news

MicroRNA profiling in MDA-MB-231 human breast cancer cell exposed to the Phaleria macrocarpa (Boerl.) fruit ethyl acetate fraction (PMEAF) through IIlumina Hi-Seq technologies and various in silico bioinformatics tools
Conclusion In conclusion, the results of this study proved that PMEAF is a promising anticancer agent with high cytotoxicity against MDA-MB-231 breast cancer cells and it induced apoptotic cell death mechanism through the regulation of miRNAs. PMEAF might be the best candidate for developing more potent anticancer drugs or chemo preventive supplements. Graphical abstract
Source: Journal of Ethnopharmacology - December 5, 2017 Category: Drugs & Pharmacology Source Type: research

Two weeks to bowel cancer?
There’s no doubt antibiotics have saved a lot of lives. But because they’ve been overprescribed for so many years we’ve ended up with a slew of health problems. For one thing, overuse of antibiotics wreaks havoc on your microbiome… That’s your body’s ecosystem. Your microbiome has 100 trillion or so bacteria, viruses and fungi. It affects just about every organ and body system. Some of these gut bugs cause disease and infection. But other good bacteria are called “probiotics.” They boost your immune system. They help you digest your food and turn it into vitamins. But in ...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Randall Hall Tags: Cancer Health Men's Health Source Type: news

New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines
Conclusion Fourteen compounds were isolated from chloroform fraction of G. mangostana fruit hulls. Cytotoxic properties exhibited by the isolated xanthones from G. mangostana reinforce the avail of it as a natural cytotoxic agent against various cancers. These evidences could provide relevant bases for the scientific rationale of using G. mangostana in anti-cancer treatment. Graphical abstract
Source: Journal of Ethnopharmacology - January 25, 2017 Category: Drugs & Pharmacology Source Type: research

Phytochemical constituents, nutritional values, phenolics, flavonols, flavonoids, antioxidant and cytotoxicity studies on Phaleria macrocarpa (Scheff.) Boerl fruits
Conclusion: The methanol extract and the ethyl acetate fraction of P. macrocarpa fruits exhibited good nutritional values, good antioxidant and cytotoxic activities, and merits further investigation to identify the specific compound(s) responsible for these activities.
Source: BMC Complementary and Alternative Medicine - May 8, 2014 Category: Complementary Medicine Authors: Ma Ma LaySaiful Anuar KarsaniSadegh MohajerSri Nurestri Abd Malek Source Type: research