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Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol
Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting medical chart,” says Blendermann, a real estate agent in Prior Lake, Minnesota. Yet Blendermann’s routine lab results weren’t alarming. At checkups, her low-density lipoprotein (LDL), or “bad,” cholesterol hovered around the 100 milligrams-per-...
Source: Science of Aging Knowledge Environment - March 16, 2023 Category: Geriatrics Source Type: research

The role of medications in successful aging
Climacteric. 2021 May 12:1-8. doi: 10.1080/13697137.2021.1911991. Online ahead of print.ABSTRACTSuccessful aging includes good health and low levels of disability. To that end, primary prevention is far better than managing subsequent organ damage. When medication is needed to prevent or manage disease, the preferred choice should be associated with the greatest benefits and fewest adverse effects. Cardiovascular diseases are the leading cause of morbidity and mortality in postmenopausal women worldwide. Considering disease-adjusted life years, other leading causes are chronic obstructive pulmonary disease, diabetes mellit...
Source: Climacteric - May 12, 2021 Category: Geriatrics Authors: R D Langer Source Type: research

Effect of the COVID-19 lockdown on disease recognition and utilisation of healthcare services in the older population in Germany: a cross-sectional study
ConclusionThe data suggest that organisational changes were adopted quickly by practice management but also raise concerns about the maintenance of routine care. Prospective studies should evaluate the long-term effects of lockdowns on patient-related outcomes.
Source: Age and Ageing - November 17, 2020 Category: Geriatrics Source Type: research

308 Association of Diabetes and Frailty with Mortality in Middle-Aged and Older Europeans
ConclusionFrailty and pre-frailty are independent risk factors for mortality in diabetics. The identification of frailty is important for the risk-stratification and management of middle aged and older patients with diabetes and should be included in the routine assessment of these high-risk individuals.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

Atorvastatin in the treatment of lithium-induced nephrogenic diabetes insipidus: the protocol of a randomized controlled trial
Lithium is the gold-standard treatment for bipolar disorder, is highly effective in major depressive disorder, and is being investigated for therapeutic benefits in dementia, stroke, and even cancer. Approximately 350,000 Canadians use lithium and more could benefit. Despite this, clinicians are avoiding lithium, largely due to fear of renal toxicity, including irreversible chronic kidney disease (CKD). Nephrogenic Diabetes Insipidus (NDI) occurs in 20% of lithium users and independently predicts a 2-3 times increased risk of CKD.
Source: The American Journal of Geriatric Psychiatry - February 28, 2019 Category: Geriatrics Authors: Jocelyn Fotso Soh, Gabriela Torres-Platas, Serge Beaulieu, Outi Mantere, Robert Platt, Istvan Mucsi, Sybille Saury, Suzane Renaud, Andrea Levinson, Ana Andreazza, Benoit Mulsant, Daniel Mueller, Ayal Schaffer, Annemiek Dols, Nancy Low, Pablo Cervantes, Na Tags: Poster Number: EI - 48 Source Type: research

The relationship between discharge medications and falls in post-hospitalised older adults: A 6-month follow-up.
CONCLUSION: Falls prevention strategies, other than hospital discharge medication management in the postdischarge older adults, warrant investigation. PMID: 30806033 [PubMed - as supplied by publisher]
Source: Australasian Journal on Ageing - February 25, 2019 Category: Geriatrics Authors: Lam K, Lee DA, Lalor AF, Stolwyk R, Russell G, Brown T, McDermott F, Haines TP Tags: Australas J Ageing Source Type: research

Prevalence of Chronic Cancer and No-Cancer Pain in Elderly Hospitalized Patients: Elements for the Early Assessment of Palliative Care Needs
ConclusionPain is a critical underestimated problem in elderly patients. A timely systematic evaluation of the pain would call attention to palliative care needs and reduce the negative effects of uncontrolled pain on the quality of life.
Source: International Journal of Gerontology - July 10, 2018 Category: Geriatrics Source Type: research

Three ‐Year Changes in Physical Activity and Decline in Physical Performance Over 9 Years of Follow‐Up in Older Adults: The Invecchiare in Chianti Study
ConclusionMaintaining or increasing PA levels may attenuate age‐associated physical performance decline.
Source: Journal of the American Geriatrics Society - February 28, 2017 Category: Geriatrics Authors: David Martinez ‐Gomez, Stefania Bandinelli, Vieri Del‐Panta, Kushang V. Patel, Jack M. Guralnik, Luigi Ferrucci Tags: Clinical Investigation Source Type: research

Physical activity and exercise as countermeasures to physical frailty and sarcopenia.
Abstract The identification of cost-effective interventions that improve the health status and prevent disability in old age is one of the most important public health challenges. Regular physical activity is the only intervention that has consistently been shown to improve functional health and energy balance and to reduce the risk of cardiovascular disease, stroke, diabetes, several cancers, depression and falls. In advanced age, physical activity is also effective at mitigating sarcopenia, restoring robustness, and preventing/delaying the development of disability. On the other hand, physical inactivity is reco...
Source: Aging Clinical and Experimental Research - February 7, 2017 Category: Geriatrics Authors: Marzetti E, Calvani R, Tosato M, Cesari M, Di Bari M, Cherubini A, Broccatelli M, Savera G, D'Elia M, Pahor M, Bernabei R, Landi F, SPRINTT Consortium Tags: Aging Clin Exp Res Source Type: research

Association Between Carbohydrate Nutrition and Successful Aging Over 10 Years
Conclusions: Consumption of dietary fiber from breads/cereals and fruits independently influenced the likelihood of aging successfully over 10 years. These findings suggest that increasing intake of fiber-rich foods could be a successful strategy in reaching old age disease free and fully functional.
Source: Journals of Gerontology Series A: Biological Sciences and Medical Sciences - September 10, 2016 Category: Geriatrics Authors: Gopinath, B., Flood, V. M., Kifley, A., Louie, J. C. Y., Mitchell, P. Tags: Research Article Source Type: research

Risk factors for low back pain and sciatica in elderly men—the MrOS Sweden study
Conclusions</div>in older men with LBP and SCI, anatomical abnormalities such as vertebral fractures, metastases, central or lateral spinal stenosis or degenerative conditions may only in part explain prevalent symptoms and disability. Social and lifestyle factors must also be evaluated since they are associated not only with unspecific LBP but also with LBP with SCI.</span>
Source: Age and Ageing - September 7, 2016 Category: Geriatrics Source Type: research

Multimorbidity is associated with anxiety in older adults in the Health and Retirement Study
ConclusionNumber of medical conditions and specific conditions are associated with increased occurrence of elevated anxiety. Compared with elevated depressive symptoms, anxiety is associated with greater multimorbidity. As anxiety and depression cause significant morbidity, it may be beneficial to consider these mental health symptoms when evaluating older adults with multimorbidity. Published 2016. This article is a U.S. Government work and is in the public domain in the USA
Source: International Journal of Geriatric Psychiatry - July 20, 2016 Category: Geriatrics Authors: Christine E. Gould, Ruth O'Hara, Mary K. Goldstein, Sherry A. Beaudreau Tags: Special Issue Paper Source Type: research

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