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Total 18 results found since Jan 2013.

SARS CoV-2 infections in animals, two years into the pandemic
AbstractIn December 2019, several cases of pneumonia caused by a novel coronavirus, later identified as SARS-CoV-2, were detected in the Chinese city of Wuhan. Due to its rapid worldwide spread, on 11 March 2020 the World Health Organization declared a pandemic state. Since this new virus is genetically similar to the coronaviruses of bats, SARS-CoV-2 was hypothesized to have a zoonotic origin. Within a year of the appearance of SARS-CoV-2, several cases of infection were also reported in animals, suggesting human-to-animal and animal-to-animal transmission among mammals. Natural infection has been found in companion anima...
Source: Archives of Virology - October 7, 2022 Category: Virology Source Type: research

Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID
Discussion Among evaluated patients with long COVID, prolonged, often disabling, small-fiber neuropathy after mild SARS-CoV-2 was most common, beginning within 1 month of COVID-19 onset. Various evidence suggested infection-triggered immune dysregulation as a common mechanism.
Source: Neurology Neuroimmunology and Neuroinflammation - March 1, 2022 Category: Neurology Authors: Oaklander, A. L., Mills, A. J., Kelley, M., Toran, L. S., Smith, B., Dalakas, M. C., Nath, A. Tags: Post-infectious, Peripheral neuropathy, EMG, COVID-19 Clinical/Scientific Note Source Type: research

Potential protective role of the anti-PD-1 blockade against SARS-CoV-2 infection
Biomed Pharmacother. 2021 Jul 28;142:111957. doi: 10.1016/j.biopha.2021.111957. Online ahead of print.ABSTRACTThe outbreak of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, in December 2019, and its global dissemination became the coronavirus disease 2019 (COVID-19) pandemic declared by the World Health Organization (WHO) on 11 March 2020. In patients undergoing immunotherapy, the effect and path of viral infection remain uncertain. In addition, viral-infected mice and humans show T-cell exhaustion, which is identified after infection with SARS-CoV-2. Notably, they regain their T-cell compete...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 2, 2021 Category: Drugs & Pharmacology Authors: Annoor Awadasseid Qiang Yin Yanling Wu Wen Zhang Source Type: research

Potential therapeutic agents to COVID-19: An update review on antiviral therapy, immunotherapy, and cell therapy
Biomed Pharmacother. 2021 Mar 16;138:111518. doi: 10.1016/j.biopha.2021.111518. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2020 and coronavirus disease 19 (COVID-19) was later announced as pandemic by the World Health Organization (WHO). Since then, several studies have been conducted on the prevention and treatment of COVID-19 by potential vaccines and drugs. Although, the governments and global population have been attracted by some vaccine production projects, the presence of SARS-CoV-2-specific antiviral drugs would be an urge necessit...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - March 28, 2021 Category: Drugs & Pharmacology Authors: Mona Sadat Mirtaleb Amir Hossein Mirtaleb Hassan Nosrati Jalal Heshmatnia Reza Falak Reza Zolfaghari Emameh Source Type: research

Coronavirus and its terrifying inning around the globe: The pharmaceutical cares at the main frontline
Chemosphere. 2021 Feb 16;275:129968. doi: 10.1016/j.chemosphere.2021.129968. Online ahead of print.ABSTRACTA novel coronavirus (2019-nCoV) is an acute life-threatening disease, emerged in China, which imposed a potentially immense toll in terms of public health emergency due to high infection rate and has a devastating economic impact that attracts the world's attention. After that, on January 30, 2020, it was officially declared as a global pandemic by World Health Organization (WHO). The International Committee on Taxonomy of Viruses (ICTV) recognized it as a Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) a...
Source: Chemosphere - March 2, 2021 Category: Chemistry Authors: Muneeb Ullah Abdul Wahab Sumbul Saeed Shahid Ullah Khan Haider Ali Shah Humayun Banzeer Ahsan Abbasi Shah Saud Khalid Naveed Sher Aslam Khan Shah Fahad Source Type: research

The Great Vaccine Race: Inside the Unprecedented Scramble to Immunize the World Against COVID-19
The cleverest of enemies thrive on surprise attacks. Viruses—and coronaviruses in particular—know this well. Remaining hidden in animal hosts for decades, they mutate steadily, sometimes serendipitously morphing into more effective and efficient infectious agents. When a strain with just the right combination of genetic codes that spell trouble for people makes the leap from animal to human, the ambush begins. Such was the case with SARS-CoV-2, the coronavirus behind COVID-19, and the attack was mostly silent and insidious at first. Many people infected with SARS-CoV-2 remained oblivious as they served as the v...
Source: TIME: Health - September 10, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Magazine Source Type: news

COVID-19: respuesta inmune y perspectivas terap éuticas.
COVID-19: respuesta inmune y perspectivas terapéuticas. Rev Peru Med Exp Salud Publica. 2020 Apr-Jun;37(2):312-319 Authors: Lozada-Requena I, Núñez Ponce C Abstract Disease caused by the new coronavirus (COVID-19) is characterized by fever, cough, and affection of the lower respiratory tract. It is associated with age, comorbidities and a weakened immune system. Typically, lymphopenias have been evidenced in severe cases and an excessive production of inflammatory cytokines (cytokine storm), which would explain the role of the hyperinflammatory response in the pathogenesis of COVID-19. Secondary inf...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - September 4, 2020 Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research