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Specialty: Infectious Diseases
Infectious Disease: Flu Pandemic
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Total 203 results found since Jan 2013.
Prevalence and associated outcomes of co-infection between SARS-CoV-2 and influenza: a systematic review and meta-analysis
Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was reported in late 2019, the ensuing coronavirus disease 2019 (COVID-19) pandemic has spread rapidly across the globe, causing an unprecedented health burden in many countries. As of June 7, 2023, the COVID-19 pandemic has caused 767.7 million infections and 6.9 million deaths worldwide [1]. Although the World Health Organization declared the end of the pandemic emergency on May 5, 2023 [2], endemics remain possible as the virus continues to undergo genetic mutations [3].
Source: International Journal of Infectious Diseases - August 28, 2023 Category: Infectious Diseases Authors: Xiaolong Yan, Ke Li, Zhiqun Lei, Jiayao Luo, Qi Wang, Sheng Wei Source Type: research
Vaccine-induced and hybrid immunity to SARS-CoV-2 after three or four doses of BNT162b2 - results from 22 months follow-up of a healthcare workers cohort, Israel, 2020-2022
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has killed at least seven million worldwide since its emergence in China in late 2019 [1] and became the most significant global health crisis since the 1918 influenza pandemic [2]. In order to mitigate the spread of the pandemic, non-pharmaceutical interventions such as protective equipment and social distancing as well as the rapid development and mass implementation COVID-19 vaccines, have been rolled out to prevent death, reduce the spread and severity of disease, and protect healthcare systems from becoming overwhelmed [2].
Source: International Journal of Infectious Diseases - August 10, 2023 Category: Infectious Diseases Authors: Michael Edelstein, Karine Wiegler Beiruti, Hila Ben-Amram, Netta Beer, Christian Sussan, Perachel Batya, Salman Zarka, Kamal Abu Jabal Source Type: research
Paradigm shift of respiratory viruses causing lower respiratory tract infection in children during COVID-19 pandemic in India
Conclusions: The COVID-19 pandemic significantly impacted the frequency and pattern of respiratory viruses among hospitalized children with ALRTIs in India.
Source: The Journal of Infection in Developing Countries - July 26, 2023 Category: Infectious Diseases Authors: Mannat Kang, Subhabrata Sarkar, Suresh Kumar Angurana, Pankaj Singh, Meenakshi Rana, Ishani Bora, Rishi Chetanya, Bharatendu Singh, Jayashree Muralidharan, Radha Kanta Ratho Source Type: research
Lack of neutralizing antibodies against influenza A viruses in adults during the 2022/2023 winter season – a serological study using retrospective samples collected in Hong Kong
Hong Kong adopted long and stringent non-pharmaceutical interventions during the period of the coronavirus disease (COVID-19) pandemic. A significantly decreased activity of influenza A viruses was also observed since 2020 as recorded by the weekly influenza surveillance (https://www.chp.gov.hk/en/resources/29/304.html), especially after the social distancing and mandatory mask-wearing regulation came into effect [1]. It is expected that influenza virus outbreak will re-emerge after easing of these restrictions in post COVID-19 era.
Source: International Journal of Infectious Diseases - July 20, 2023 Category: Infectious Diseases Authors: Weiwen Liang, Huibin Lv, Chunke Chen, Yuanxin Sun, David S Hui, Chris Ka Pun Mok Tags: Short Communication Source Type: research
Picolinic acid is a broad-spectrum inhibitor of enveloped virus entry that restricts SARS-CoV-2 and influenza A virus in vivo
Cell Rep Med. 2023 Jul 13:101127. doi: 10.1016/j.xcrm.2023.101127. Online ahead of print.ABSTRACTThe COVID-19 pandemic highlights an urgent need for effective antivirals. Targeting host processes co-opted by viruses is an attractive antiviral strategy with a high resistance barrier. Picolinic acid (PA) is a tryptophan metabolite endogenously produced in mammals. Here, we report the broad-spectrum antiviral activity of PA against enveloped viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), flaviviruses, herpes simplex virus, and parainfluenza virus. Mechanistic studies ...
Source: Herpes - July 18, 2023 Category: Infectious Diseases Authors: Rohan Narayan Mansi Sharma Rajesh Yadav Abhijith Biji Oyahida Khatun Sumandeep Kaur Aditi Kanojia Christy Margrat Joy Raju Rajmani Pallavi Raj Sharma Sharumathi Jeyasankar Priya Rani Radha Krishan Shandil Shridhar Narayanan Durga Chilakalapudi Rao Vijaya Source Type: research
A seesaw effect between COVID-19 and influenza during 2020-2023 in WHO regions
CONCLUSIONS: Influenza activity and former seasonal epidemiological patterns are shaken by the COVID-19 pandemic. Their activities are moderately and above inversely correlated, oppressing and competing with each other, showing a seesaw effect. In the post-pandemic era of COVID-19, the seesaw trends may be more prominent, prompting the possibility of using one another as early warning signals for future estimates and conducting optimized annual vaccine campaigns.PMID:37191650 | DOI:10.2196/44970
Source: Euro Surveill - May 16, 2023 Category: Infectious Diseases Authors: Qing Wang Mengmeng Jia Mingyue Jiang Wei Liu Jin Yang Peixi Dai Yanxia Sun Jie Qian Weizhong Yang Luzhao Feng Source Type: research
Differences in clinical characteristics and outcomes between COVID-19 and influenza in critically ill adult patients: a national database study
Prior to the coronavirus disease 2019 (COVID-19) pandemic, influenza was the most frequent cause of viral respiratory pneumonia requiring intensive care unit (ICU) admission. Few studies have compared the characteristics and outcomes of critically ill patients with COVID-19 and influenza.
Source: Journal of Infection - May 16, 2023 Category: Infectious Diseases Authors: Diane Naouri, Tai Pham, Martin Dres, Albert Vuagnat, Ga ëtan Beduneau, Alain Mercat, Alain Combes, Antoine Kimmoun, Matthieu Schmidt, Alexandre Demoule, Matthieu Jamme Source Type: research
Virus Infections in Older People
Subcell Biochem. 2023;103:149-183. doi: 10.1007/978-3-031-26576-1_8.ABSTRACTOlder people are more prone to viral infections, and often have worse outcomes. This was well demonstrated during the COVID-19 pandemic, where a disproportionate number of deaths occurred in the oldest and frailest people. The assessment of the older person with a viral infection is complicated by the high prevalence of multiple comorbidities and sensory or cognitive impairment. They often present with common geriatric syndromes such as falls or delirium, rather than the more typical features of a viral illness in younger people. Comprehensive geri...
Source: Herpes - April 29, 2023 Category: Infectious Diseases Authors: Roy L Soiza Chiara Scicluna Sana Bilal Source Type: research
Cyanometabolites: molecules with immense antiviral potential
Arch Microbiol. 2023 Apr 3;205(5):164. doi: 10.1007/s00203-023-03514-y.ABSTRACTCyanometabolites are active compounds derived from cyanobacteria that include small low molecular weight peptides, oligosaccharides, lectins, phenols, fatty acids, and alkaloids. Some of these compounds may pose a threat to human and environment. However, majority of them are known to have various health benefits with antiviral properties against pathogenic viruses including Human immunodeficiency virus (HIV), Ebola virus (EBOV), Herpes simplex virus (HSV), Influenza A virus (IAV) etc. Cyanometabolites classified as lectins include scytovirin (S...
Source: Herpes - April 3, 2023 Category: Infectious Diseases Authors: Uma Singh Harsh A Gandhi None Nikita Jaydeep Bhattacharya Ravi Tandon G L Tiwari Richa Tandon Source Type: research
Non-pharmaceutical interventions for COVID-19 reduced the incidence of infectious diseases: a controlled interrupted time-series study
ConclusionsNPIs for COVID-19 could effectively control the prevalence of infectious diseases, with patterns of risk varying by socioeconomic status. These findings have important implications for informing targeted strategies to prevent infectious diseases.
Source: Infectious Diseases of Poverty - March 9, 2023 Category: Infectious Diseases Source Type: research
Exogenous Players in Mitochondria-Related CNS Disorders: Viral Pathogens and Unbalanced Microbiota in the Gut-Brain Axis
Biomolecules. 2023 Jan 13;13(1):169. doi: 10.3390/biom13010169.ABSTRACTBillions of years of co-evolution has made mitochondria central to the eukaryotic cell and organism life playing the role of cellular power plants, as indeed they are involved in most, if not all, important regulatory pathways. Neurological disorders depending on impaired mitochondrial function or homeostasis can be caused by the misregulation of "endogenous players", such as nuclear or cytoplasmic regulators, which have been treated elsewhere. In this review, we focus on how exogenous agents, i.e., viral pathogens, or unbalanced microbiota in the gut-b...
Source: Herpes - January 21, 2023 Category: Infectious Diseases Authors: Irene Righetto Matteo Gasparotto Laura Casalino Marcella Vacca Francesco Filippini Source Type: research
