Filtered By:
Drug: Dexamethasone
Vaccination: Vaccines

This page shows you your search results in order of date.

Order by Relevance | Date

Total 155 results found since Jan 2013.

Fighting cytokine storm and immunomodulatory deficiency: By using natural products therapy up to now
A novel coronavirus strain (COVID-19) caused severe illness and mortality worldwide from 31 December 2019 to 21 March 2023. As of this writing, 761,071,826 million cases have been diagnosed worldwide, with 6,879,677 million deaths accorded by WHO organization and has spread to 228 countries. The number of deaths is closely connected to the growth of innate immune cells in the lungs, mainly macrophages, which generate inflammatory cytokines (especially IL-6 and IL-1β) that induce “cytokine storm syndrome” (CSS), multi-organ failure, and death. We focus on promising natural products and their biologically active chemica...
Source: Frontiers in Pharmacology - April 12, 2023 Category: Drugs & Pharmacology Source Type: research

The effectiveness of dexamethasone as a combination therapy for COVID-19
Acta Pharm. 2022 Apr 13;72(3):345-358. doi: 10.2478/acph-2022-0030. Print 2022 Sep 1.ABSTRACTCoronavirus disease 2019 (COVID-19) was reported as a global pandemic in March 2020 after invading many countries and leaving behind tens of thousands of infected patients in a brief time span. Approval of a few vaccines has been obtained and their efficacy of varying degrees established. Still, there is no effective pharmaceutical agent for the treatment of COVID-19 though several drugs are undergoing clinical trials. Recent studies have shown that dexamethasone, a corticosteroid, can reduce the rate of COVID-19-related mortality ...
Source: Acta Pharmaceutica - January 18, 2023 Category: Drugs & Pharmacology Authors: Nader Namazi Source Type: research

Myoclonus status revealing COVID 19 infection
DISCUSSION: Our patient presented with acute isolated multifocal myoclonus status without cognitive impairment. These movements were prominent, spontaneous, worsened by action, and sensitive to touch and sound. The anatomical source of this myoclonus could be cortical or subcortical despite the absence of evident EEG discharges. Several diseases can cause acute myoclonus such as severe hypoxia, metabolic disturbances, and paraneoplastic syndromes. these diagnoses were ruled out in our patient. Post-vaccinal origin was also suggested, but its accountability was not proven. Thus, the two hypothetic etiologies raised were eit...
Source: Herpes - November 29, 2022 Category: Infectious Diseases Authors: Dina Ben Mohamed Rania Zouari Jihen Ketata Fatma Nabli Samir Blel Samia Ben Sassi Source Type: research

Prognostic factors of 30-day mortality in patients with COVID-19 pneumonia under standard remdesivir and dexamethasone treatment
Although some studies have reported prognostic factors for coronavirus disease 2019 (COVID-19), they were conducted before standard treatment with remdesivir and dexamethasone was implemented. This retrospective, observational study was conducted to evaluate various prognostic factors in patients with COVID-19 pneumonia receiving standard treatment with remdesivir and dexamethasone. Of 99 patients with COVID-19 pneumonia, 68 (68.7%) died within 30 days of hospitalization. The mean age was 71.3 years. Remdesivir and dexamethasone were administered to 80 (80.8%) and 84 (84.8%) patients, respectively. Early antibiotic treatme...
Source: Medicine - September 23, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Reactive synovitis of the knee joint after COVID ‐19 vaccination: The first ultrastructural analysis of synovial fluid
ConclusionCase reports on patients undergoing COVID-19 vaccination should be examined in order to detect rare and long-term side-effects. This is the first report to present the outcomes of an ultrastructural analysis of post-vaccination synovitis.
Source: International Journal of Rheumatic Diseases - August 5, 2022 Category: Rheumatology Authors: Eliska Vanaskova, Petr Kelbich, Tomas Novotny Tags: CASE REPORT Source Type: research

Outcomes of SARS-CoV-2 Infection in Unvaccinated Compared With Vaccinated Solid Organ Transplant Recipients: A Propensity Matched Cohort Study
Background. Solid organ transplant (SOT) recipients are at high risk for complications from coronavirus disease 2019 (COVID-19). Vaccination may mitigate this risk; however, immunogenicity appears to be significantly impaired, with reports of increased risk of breakthrough infection. It is unknown if vaccine breakthrough infections are milder or as severe as infections in unvaccinated patients. Methods. We performed a multicenter matched cohort study between March 2020 and September 2021 to assess influence of COVID-19 vaccination on outcomes of COVID-19 infection. Treatment characteristics and disease severity ...
Source: Transplantation - August 1, 2022 Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research

Prolonged COVID-19 in an Immunocompromised Patient Treated with Obinutuzumab and Bendamustine for Follicular Lymphoma
Intern Med. 2022 May 31. doi: 10.2169/internalmedicine.9136-21. Online ahead of print.ABSTRACTA patient with follicular lymphoma treated with obinutuzumab and bendamustine experienced prolonged coronavirus disease-2019 (COVID-19). One month after the symptoms transiently improved, the patient experienced exacerbated COVID-19 symptoms. The patient recovered from COVID-19 with remdesivir and dexamethasone and was discharged 77 days after the disease onset. The patient completed a primary series of SARS-CoV-2 vaccinations on day 176, but the anti-spike protein IgG was not detected later. A careful observation to detect any su...
Source: Internal Medicine - June 1, 2022 Category: Internal Medicine Authors: Yayoi Ueda Shoji Asakura Sae Wada Takashi Saito Tomofumi Yano Source Type: research