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P38 An audit of excipients of one manufacturers unlicensed liquid preparations in a tertiary paediatric hospital
Conclusion Unlicensed medicines and medicines that are used in neonate and paediatric patients must be carefully assessed for excipients before use.1–3 A risk benefit assessment4 should be conducted to establish if an unlicensed medicine should be used and prescribers notified of any excipients of concern. References Annex to the European Commission guideline on ‘Excipients in the labelling and package leaflet of medicinal products for human use’ (SANTE-2017-11668). Available at: www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003412.pdf European Medicines Agency. Committ...
Source: Archives of Disease in Childhood - April 20, 2022 Category: Pediatrics Authors: Worrall, M., Fitzpatrick, A., Fanning, J. Tags: Oral presentations Source Type: research

P04 Variability in concentration of oral liquid medicines prescribed for children in England- an analysis
Conclusion Oral liquid medicines dispensed for children in England vary considerably in terms of concentration. For the relatively few drugs for which there is a nationally recommended standard concentration, significant variation still exists. The continued use of multiple concentrations for the same API potentially poses a significant risk to patient safety. Further national standardisation is required, and methods of driving adoption of such recommendations need to be developed. Reference Neonatal and Paediatric Pharmacists Group and Royal College of Paediatrics and Child Health, UK. Using Standardised Concentrations o...
Source: Archives of Disease in Childhood - April 20, 2022 Category: Pediatrics Authors: Wignell, A., Gill, A., Duncan, J. Tags: Oral presentations Source Type: research

P05 A project to rationalise the prescribing of unlicensed specials for children in a UK clinical commissioning group
Conclusion Although work has been undertaken at national level to standardise concentrations of unlicensed liquid medicines,2 this work has highlighted that there is still much to be done to reduce the variability in concentrations of prescribed medicines and the potential harm associated with this. The number of queries received from colleagues within primary care has emphasised a need for greater understanding of prescribing and supply of unlicensed medicines to children, as well as clear lines of communication between healthcare sectors. The specific knowledge and skills of specialist paediatric pharmacists are highly v...
Source: Archives of Disease in Childhood - April 20, 2022 Category: Pediatrics Authors: Cooper, H., Abumehdi, S. Tags: Oral presentations Source Type: research

SP2 NPPG/RCPCH position statement: using standardised concentrations of unlicensed liquid medicines in children. How well has it been adopted nationally?
Conclusion The NPPG/RCPCH position statement has helped drive standardisation to some extent, though work is needed to understand how best to support practitioners implementing these and any future recommendations. Reference Neonatal and Paediatric Pharmacists Group and Royal College of Paediatrics and Child Health, UK. Using Standardised Concentrations of Unlicensed Liquid Medicines in Children. April 2020. Available at: https://nppg.org.uk/wp-content/uploads/2020/04/NPPG-Position-Statement-18-01-V5-April-2020.pdf (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - April 20, 2022 Category: Pediatrics Authors: Wignell, A., Cooper, H., Duncan, J., Gill, A. Tags: Oral presentations Source Type: research

The climate crisis is also a child rights crisis
The Royal College of Paediatrics and Child Health (RCPCH) recently published a new position statement on the climate crisis ahead of the 2021 United Nations Climate Change Conference in Glasgow (the 26th Conference of the Parties or COP26).1 The statement reminds us that children have the right to health, including healthcare and other fundamental economic and social rights. A child rights-based approach builds on a human rights approach but includes the specific needs of children. Furthermore, many international agreements, including the 2030 Agenda for Sustainable Development and the Paris Agreement, affirm countries&rsq...
Source: Archives of Disease in Childhood - April 20, 2022 Category: Pediatrics Authors: Ali, H., Firth, A., Leaf, A., Vivehananthan, C., Shanmugavadivel, D., Ajayi-Obe, E., Halbert, J., Gow, J. H., Thomas, M., de Sousa, P., Waterston, T., O'Hare, B. Tags: Editorial Source Type: research

Appendiceal involvement in pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a diagnostic challenge in the coronavirus disease (COVID) era
ConclusionIn addition to free fluid, prominent lymphadenopathy, and inflammatory changes in the right iliac fossa, we found abnormal long-segment ileal thickening and appendicitis to be frequent findings. Recognition of appendiceal involvement as a component of the PIMS-TS spectrum should help clinicians avoid unnecessary surgical intervention as part of a multidisciplinary team approach. (Source: Pediatric Radiology)
Source: Pediatric Radiology - April 8, 2022 Category: Radiology Source Type: research

NHS 111 Clinical Assessment Services: paediatric consultations
Around the UK, commissioners have different models for delivering NHS 111, General Practice (GP) out-of-hours and urgent care services, focusing on telephony to help deliver urgent and emergency care. During the (early phases of the) COVID-19 pandemic, NHS 111 experienced an unprecedented volume of calls. At any time, 25%–30% of calls relate to children and young people (CYP). In response, the CYP’s Transformation and Integrated Urgent Care teams at NHS England and NHS Improvement (NHSE/I) assisted in redeploying volunteer paediatricians into the integrated urgent care NHS 111 Clinical Assessment Services (CAS)...
Source: Archives of Disease in Childhood - February 17, 2022 Category: Pediatrics Authors: Stilwell, P. A., Fissler, S., Burkitt, S., Smith, B., Stuttard, G., Kenny, S., Evans, D., Maconochie, I. Tags: COVID-19 Short report Source Type: research

Call for a universal PIMS-TS/MIS-C case definition
In April 2020, reports emerged of a new paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Numerous clinical uncertainties of PIMS-TS are still contested regularly in clinical practise today. These include distinguishing PIMS-TS from other common causes of childhood febrile illness and its pathogenesis. Disparity in clinical guidance exacerbates this uncertainty. This letter calls for a universal PIMS-TS case definition, which could improve coherency in clinical practise and research. The first case definition released by the Royal College of Paediatrics and Child Health in May 20...
Source: Archives of Disease in Childhood - February 17, 2022 Category: Pediatrics Authors: Rhys-Evans, S. Tags: COVID-19 PostScript Source Type: research

Case for persuasion in parental informed consent to promote rational vaccine choices
There have been calls for mandatory vaccination legislation to be introduced into the UK in order to tackle the national and international rise of vaccine-preventable disease. While some countries have had some success associated with mandatory vaccination programmes, the Royal College of Paediatrics and Child Health (RCPCH) insist this is not a suitable option for the UK, a country which has seen historical opposition to vaccine mandates. There is a lack of comprehensive data to demonstrate a direct link between mandatory vaccination legislation and increased uptake. While there are examples whereby there has been an impr...
Source: Journal of Medical Ethics - January 21, 2022 Category: Medical Ethics Authors: O'Neill, J. Tags: Original research Source Type: research

Addressing recruitment and retention in paediatrics: a pipeline to a brighter future
Conclusions While some issues share similarities with other specialties in difficulty, much of the context and potential remedies within paediatrics are distinct. A strategic, multi-agency collaborative approach is required urgently to address the significant issues that face both paediatrics and the healthcare system. (Source: Archives of Disease in Childhood - Education and Practice)
Source: Archives of Disease in Childhood - Education and Practice - January 20, 2022 Category: Pediatrics Authors: Mallett, P., Thompson, A., Bourke, T. Tags: Learning and teaching, COVID-19 Source Type: research

Retinopathy of prematurity occurrence and evaluation of screening policy in a large tertiary Greek cohort
ConclusionsThe frequency of ROP observed in this cohort was as low as that reported in other developed countries. The currently used screening criteria permitted identification of all infants who were at risk and, therefore, need not be changed. (Source: International Ophthalmology)
Source: International Ophthalmology - October 21, 2019 Category: Opthalmology Source Type: research

Evaluation of a questionnaire to measure parent/carer and child/young person experience of nhs epilepsy services
The “National Epilepsy 12 Audit” aimed to measure and improve the quality of care provided by the National Health Service (NHS) to children and young people with seizures and epilepsies in the United Kingdom (UK) [1]. The audit was co-ordinated by the Royal College of Paediatrics and Child Health in partnership with Epilepsy Action and the British Paediatric Neurology Association, and includes paediatric departments which see children aged 1 month to 16 years with suspected or diagnosed epilepsies [1]. (Source: Seizure: European Journal of Epilepsy)
Source: Seizure: European Journal of Epilepsy - November 2, 2018 Category: Neurology Authors: Rishma Maini, Martin Kirkpatrick, Aileen McCafferty, Colin Dunkley, Simon Ogston, Fiona Williams Source Type: research

Understanding barriers for research involvement among paediatric trainees: a mixed methods study
Child Health research is reported to be at worryingly low level by the Royal College of Paediatrics and Child Health. Recent survey showed that 54.5% of paediatric consultants in the United Kingdom do not do a... (Source: BMC Medical Education)
Source: BMC Medical Education - July 13, 2018 Category: Universities & Medical Training Authors: Khurram Mustafa, Carolyn Czoski Murray, Emma Nicklin, Adam Glaser and Jacqueline Andrews Tags: Research article Source Type: research

Developing standards of care for children with ongoing health needs.
Abstract Emeritus Professor Alan Glasper, from the University of Southampton, discusses a recently published report from a consortium of health agencies led by the Royal College of Paediatrics and Child Health. PMID: 29791224 [PubMed - in process] (Source: British Journal of Nursing)
Source: British Journal of Nursing - May 24, 2018 Category: Nursing Authors: Glasper A Tags: Br J Nurs Source Type: research

[Editorial] Solitary confinement of children and young people
Last week, in a joint statement, the British Medical Association (BMA), the Royal College of Psychiatrists, and the Royal College of Paediatrics and Child Health called for an end to the solitary confinement of children and young people held in UK detention facilities. According to a survey from the HM Inspectorate of Prisons, 38% of boys detained in the UK have spent time in solitary confinement, physically and socially isolated from others, with almost no purposeful interaction or environmental stimuli, for periods that can stretch for up to 80 days. (Source: LANCET)
Source: LANCET - April 27, 2018 Category: General Medicine Authors: The Lancet Tags: Editorial Source Type: research