Two Years of Calorie Restriction Produces Thymic Regrowth in Humans
We report that about 14% CR for 2 years in healthy humans improved thymopoiesis and was correlated with mobilization of intrathymic ectopic lipid. CR-induced transcriptional reprogramming in adipose tissue implicated pathways regulating mitochondrial bioenergetics, anti-inflammatory responses, and longevity. Expression of the gene Pla2g7 is inhibited in humans undergoing CR. Deletion of Pla2g7 in mice showed decreased thymic lipoatrophy, protection against age-related inflammation, lowered NLRP3 inflammasome activation, and improved metabolic health. Therefore, the reduction of PLA2G7 may mediate the immunometabolic effect...
Source: Fight Aging! - February 11, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

#HealthTechDeals Episode 08: M & A special! ThirtyMadison & Nurx, Concerto Care, Kindbody, Calm, Withings all at it!
Will Jessica stop laughing? Will we get the intro right? Who knows! 2022 is a big M&A year and this episode is no exception: ThirtyMadison and Nurx have merged, combined they have $300 million in revenue; Concerto Care acquires Crown Health; Kindbody buys Vios Fertility Institute; Calm merges with Ripple Health; Withings buys 8Fit. -By Matthew Holt (Source: The Health Care Blog)
Source: The Health Care Blog - February 9, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Deals 8Fit calm Concerto Health Crown Health HealthTechDeals Kindbody Nurx Ripple Health ThirtyMadison Vios Fertility Institute Withings Source Type: blogs

Pregnancy After Endometrial Ablation: Study Review
Pregnancy After Endometrial Ablation| Dr Monteith reviews leading studies examining pregnancy after endometrial ablation. The post Pregnancy After Endometrial Ablation: Study Review appeared first on A Personal Choice. (Source: Tubal Reversal Blog)
Source: Tubal Reversal Blog - February 6, 2022 Category: Reproduction Medicine Authors: Dr. Monteith Tags: Dr. Berger Dr. Monteith endometrial ablation reversing tied tubes tubal reversal doctors tubal reversal surgery untie tubes why tubal reversal Is pregnancy possible pregnancy after ablation pregnancy after endometrial ablation pregna Source Type: blogs

Fight Aging! Newsletter, February 7th 2022
In this study, we used accelerometer measurements (1) to examine the association of physical activity and mortality in a population-based sample of US adults and (2) to estimate the number of deaths prevented annually with modest increases in moderate-to-vigorous physical activity (MVPA) intensity. This analysis included 4,840 participants. Increasing MVPA by 10, 20, or 30 minutes per day was associated with a 6.9%, 13.0%, and 16.9% decrease in the number of deaths per year, respectively. We estimated that approximately 110,000 deaths per year could be prevented if US adults aged 40 to 85 years or older increased th...
Source: Fight Aging! - February 6, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Considering the Longevity of Eusocial Insect Queens
Eusocial species are characterized by reproductive and non-reproductive castes, such as the familiar division of queens and workers in common insect species. Eusociality is more common in insects and less so in other classes of life, although there are a few eusocial mammals, such as the naked mole-rat. For researchers who investigate the comparative biology of aging, one of the more interesting aspects of eusociality is that queens live longer than workers, many times longer in some species, while being genetically identical. Why is this? Comparing very similar species with divergent life spans is a desirable start...
Source: Fight Aging! - February 4, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Tubal Reversal, Endometrial Ablation, Pregnancy: Concerns
In part three of the series on pregnancy and endometrial ablation the reversal experts of A Personal Choice explain the reasoning for the risks of becoming pregnant after an endometrial ablation procedure. The cause of each of the serious risks and well as how pregnancy is possible is carefully explained. The post Tubal Reversal, Endometrial Ablation, Pregnancy: Concerns appeared first on A Personal Choice. (Source: Tubal Reversal Blog)
Source: Tubal Reversal Blog - January 30, 2022 Category: Reproduction Medicine Authors: Dr. Monteith Tags: endometrial ablation pregnancy after endometrial ablation reversing tied tubes tubal ligation tubal ligation reversal tubal reversal surgery untie tubes why tubal reversal after ablation ashermans and tubal blockage endometrial ablatio Source Type: blogs

Oura Ring (Gen3) Review: Does The Oura Ring Really Work?
The Oura Ring from Finland-based ŌURA was making waves over the past years, partly due to the technology behind the item, and in part due to well-placed PR moves. Twitter’s co-founder Jack Dorsey wears one as do NBA players; but the smart ring made waves recently following reports that it could indicate when the wearer is sick before symptoms show. In some cases, it could potentially help identify asymptomatic COVID-19 infections, which can make up to 40% of cases. Quite the ability-enhancing wearable for our non-fantasy world; but would it satisfy digital health and fitness enthusiasts? That’s what we’ll find ou...
Source: The Medical Futurist - January 25, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Lifestyle medicine E-Patients Health Sensors & Trackers Portable Medical Diagnostics Telemedicine & Smartphones review fitness tracker ring oura Gen3 smart tracker Source Type: blogs

Effects of Endometrial Ablation on Pregnancy
The tubal reversal experts of A Personal Choice provide more information on endometrial ablation, pregnancy, and tubal ligation reversal. This second article provides insight into the effects of endometrial ablation and how pregnancy is possible after endometrial ablation. The post Effects of Endometrial Ablation on Pregnancy appeared first on A Personal Choice. (Source: Tubal Reversal Blog)
Source: Tubal Reversal Blog - January 24, 2022 Category: Reproduction Medicine Authors: Dr. Monteith Tags: pregnancy after endometrial ablation reversing tied tubes tubal ligation reversal Tubal Reversal Procedure tubal reversal surgery untie tubes why tubal reversal and endometrial ablation and tubal blockage effects of endometrial ablation Source Type: blogs

Fight Aging! Newsletter, January 24th 2022
In conclusion, senolytic drugs have shown promising results in the elimination of senescent cells and in alleviating various diseases in animal models. However, in patients, there is a paucity in data on the efficacy and safety of senotherapeutics from clinical trials, including systemic effects and side-effects. In this regard it is important to assess the specificity of senolytics in killing targeted senescent cells and their cytotoxic effects, to identify reliable markers for intervention responses, to elucidate interactions with comorbidities and other drugs, and to standardise administration protocols. FOXO3...
Source: Fight Aging! - January 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Gameto Raises $20M at an Early Stage to Focus on Ovarian Aging
One of the signs of investor enthusiasm for an industry is the existence of projects that raise significant funding at a very early stage of their development. We're seeing that happen for cellular reprogramming, but companies started by well-connected individuals in other parts of the longevity industry are now raising a great deal of funding in early preclinical stages of development. This suggests that we will continue to see a growing influx of capital into the development of ways to treat aging as a medical condition, pulling more research projects out of the constraints of academia and into an environment of greater ...
Source: Fight Aging! - January 18, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Pregnancy After Endometrial Ablation And Tubal Reversal
Many women will inquire about both the possibility and risks of pregnancy after an endometrial ablation procedure. The tubal ligation reversal experts of A Personal Choice present a blog series dedicated to the risks of pregnancy after an endometrial ablation procedure. The post Pregnancy After Endometrial Ablation And Tubal Reversal appeared first on A Personal Choice. (Source: Tubal Reversal Blog)
Source: Tubal Reversal Blog - January 15, 2022 Category: Reproduction Medicine Authors: Dr. Monteith Tags: reversing tied tubes tubal ligation reversal tubal reversal surgery untie tubes why tubal reversal and endometrial ablation endometrial ablation and tubal reversal Is pregnancy possible menstrual period menstrual period after endometrial Source Type: blogs

What Does Tubal Ligation Reversal Cost? What You Need to Know
Would you like to get tubal ligation reversal but want to know what does tubal ligation reversal cost? Read on and learn more. The post What Does Tubal Ligation Reversal Cost? What You Need to Know appeared first on A Personal Choice. (Source: Tubal Reversal Blog)
Source: Tubal Reversal Blog - January 14, 2022 Category: Reproduction Medicine Authors: Dr. Monteith Tags: tubal ligation reversal cost tubal reversal what does tubal ligation reversal cost Source Type: blogs

TWiV 851: Questions are tricky
The TWiV team reviews the observation that infection with the SARS-CoV-2 Omicron variant causes reduced reproduction and pathogenesis in mice and hamsters. Click arrow to playDownload TWiV 851 (61 MB .mp3, 102 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe/twiv (Source: virology blog)
Source: virology blog - January 13, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 pandemic SARS-CoV-2 viral viruses Source Type: blogs

Essure Removal: What to Expect From Surgery
Essure removal involves several surgical techniques. Wondering what to expect from this procedure? Click now for our complete guide. The post Essure Removal: What to Expect From Surgery appeared first on A Personal Choice. (Source: Tubal Reversal Blog)
Source: Tubal Reversal Blog - December 27, 2021 Category: Reproduction Medicine Authors: Dr. Monteith Tags: Essure Essure removal Essure reversal Source Type: blogs

Women physicians with infertility [PODCAST]
“Many of us suffer in silence for myriad reasons. Being a physician with infertility presents a perfect storm of stress, anxiety, guilt, and shame – all of which we know don’t contribute to managing any medical problem. Consider what it’s like to undergo a typical cycle of in vitro fertilization. You administer nightly hormone injectionsRead more …Women physicians with infertility [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 21, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast OB/GYN Source Type: blogs