Diversity when interpreting evidence in network meta-analyses (NMAs) on similar topics: an example case of NMAs on diabetic macular oedema
ConclusionsA closer inspection of each of these trials shows how the methods, including the searches and analyses, all differ, but the findings, although presented differently and sometimes interpreted differently, were similar. (Source: Systematic Reviews)
Source: Systematic Reviews - October 7, 2023 Category: International Medicine & Public Health Source Type: research
Acute Kidney Injury from Intravitreal Anti-vascular Endothelial Growth Factor Drugs: A Systematic Review and Meta-analysis of Randomized Controlled Trials
ConclusionsIntravitreal anti-VEGF drugs were not associated with an acute kidney injury risk, regardless of which anti-VEGF drugs (aflibercept or ranibizumab) or retinal diseases (age-related macular degeneration, diabetic retinopathy/diabetic macular edema, or retinal vein occlusion) were involved.Systematic Review Protocol RegistrationPROSPERO CRD42021267854. (Source: BioDrugs)
Source: BioDrugs - September 7, 2023 Category: Drugs & Pharmacology Source Type: research
A real-world disproportionality analysis of anti-VEGF drugs from the FDA Adverse Event Reporting System
CONCLUSIONS: Our findings support the associations between anti-VEGF drugs and ocular AEs, cardiac AEs, and central nervous AEs. After intravitreal injection, attention should not only be paid to ocular symptoms, but also to systemic symptoms.PMID:37665052 | DOI:10.1080/14740338.2023.2250717 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - September 4, 2023 Category: Drugs & Pharmacology Authors: Ruishan Zhou Peiwen Lu Mingxiu He Junheng Chen Yiyang Shi Fangfang Han Yongming Cai Source Type: research
Effect of Laser Panretinal Photocoagulation Combined with Lucentis on Long-Term Visual Acuity of Patients with Retinal Arterial Macroaneurysm
CONCLUSION: Laser panretinal photocoagulation combined with lucentis can deliver with reduced incidence of adverse effects compared to laser panretinal photocoagulation treatment and hence can more effectively contribute to retinal rehabilitation of patients with retinal arterial macroaneurysm.PMID:37632971 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - August 26, 2023 Category: Complementary Medicine Authors: Sha Liu Yan Wang Source Type: research
Effect of Laser Panretinal Photocoagulation Combined with Lucentis on Long-Term Visual Acuity of Patients with Retinal Arterial Macroaneurysm
CONCLUSION: Laser panretinal photocoagulation combined with lucentis can deliver with reduced incidence of adverse effects compared to laser panretinal photocoagulation treatment and hence can more effectively contribute to retinal rehabilitation of patients with retinal arterial macroaneurysm.PMID:37632971 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - August 26, 2023 Category: Complementary Medicine Authors: Sha Liu Yan Wang Source Type: research
Effect of Laser Panretinal Photocoagulation Combined with Lucentis on Long-Term Visual Acuity of Patients with Retinal Arterial Macroaneurysm
CONCLUSION: Laser panretinal photocoagulation combined with lucentis can deliver with reduced incidence of adverse effects compared to laser panretinal photocoagulation treatment and hence can more effectively contribute to retinal rehabilitation of patients with retinal arterial macroaneurysm.PMID:37632971 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - August 26, 2023 Category: Complementary Medicine Authors: Sha Liu Yan Wang Source Type: research
Effect of Laser Panretinal Photocoagulation Combined with Lucentis on Long-Term Visual Acuity of Patients with Retinal Arterial Macroaneurysm
CONCLUSION: Laser panretinal photocoagulation combined with lucentis can deliver with reduced incidence of adverse effects compared to laser panretinal photocoagulation treatment and hence can more effectively contribute to retinal rehabilitation of patients with retinal arterial macroaneurysm.PMID:37632971 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - August 26, 2023 Category: Complementary Medicine Authors: Sha Liu Yan Wang Source Type: research
Evaluation of the efficacy of anti-vascular endothelial growth factors in diabetic macular edema with retinal inner and outer layers disorganization
ConclusionsNo statistically significant difference was found between anti-VEGF agents when treating DME patients with DRIL.In addition, we have shown that anatomically better results were obtained in those who had five or more injections, although not in terms of BCVA. (Source: Acta Diabetologica)
Source: Acta Diabetologica - August 22, 2023 Category: Endocrinology Source Type: research
A quantitative sonoelastography evaluation of ocular and periocular elasticity after intravitreal ranibizumab injection
CONCLUSION: A single dose intravitreal Ranibizumab (Lucentis®, Genentech, USA) injection does not alter the elasticity of ocular and periocular structures.PMID:37598105 | DOI:10.1016/j.jfo.2023.03.016 (Source: Journal Francais d Ophtalmologie)
Source: Journal Francais d Ophtalmologie - August 19, 2023 Category: Opthalmology Authors: N Sayin I Kocak S Pehlivano ğlu G Pekel A Er S E Bayramo ğlu A Aydin Source Type: research
Associations between vision impairment and vision-related interventions on crash risk and driving cessation: systematic review and meta-analysis
Conclusion
Impaired vision identified through a variety of measures is associated with both increased MVC involvement and cessation. Cataract surgery can reduce MVC risk. Despite literature being highly heterogeneous, this review shows that detection of vision problems and appropriate treatment are critical to road safety.
PROSPERO registration number
CRD42020172153. (Source: BMJ Open)
Source: BMJ Open - August 11, 2023 Category: General Medicine Authors: Nguyen, H., Di Tanna, G. L., Coxon, K., Brown, J., Ren, K., Ramke, J., Burton, M. J., Gordon, I., Zhang, J. H., Furtado, J., Mdala, S., Kitema, G. F., Keay, L. Tags: Open access, Ophthalmology Source Type: research
Aflibercept for Diabetic Macular Edema in Real-Life Practice in GREece: Three-Year Outcomes of the ADMIRE Study
CONCLUSION: Intravitreal aflibercept was found to be safe and effective for the treatment of DME in real-life in a Greek population. Treatment-naive patients and those who received a loading dose of five consecutive monthly injections at initiation of treatment exhibited better outcomes, suggesting that early and effective treatment may prevent vision loss.PMID:37539994 | DOI:10.1080/08820538.2023.2243308 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 4, 2023 Category: Opthalmology Authors: Irini Chatziralli Chrysa Agapitou Eleni Dimitriou Petros Kapsis Dimitrios Kazantzis Genovefa Machairoudia Odysseas Georgiadis George Theodossiadis Panagiotis Theodossiadis Source Type: research
