Painless Nasogastric Tube Placement
​A 6-year-old boy presented with intermittent abdominal pain, nausea, and vomiting. Because his abdominal examination was unremarkable, the pain intermittent, and constipation a possibility, we provided an enema along with an abdominal pain workup but no radiographs. His pain improved, the abdominal labs were unremarkable, and the child tolerated an oral fluid challenge after treatment with ondansetron.The mother was advised at discharge to return if she became concerned about her child's condition. They did return a few hours later for increased vomiting and abdominal pain. A CT scan demonstrated multiple dilated loops ...
Source: M2E Too! Mellick's Multimedia EduBlog - March 1, 2022 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

TB Wrist Joint : MRI
Xray- Frontal radiograph of wrist shows multiple osteolytic areas with surrounding sclerosis is seen involving all carpal bones and second metatarsal bone s/o  permeative type of bone destruction.MRI- MRI shows Extensive areas of altered marrow signal with osteolysis are seen involving all the carpal bones and almost the entire 2nd metacarpal bone. Similar areas of involvement are seen in the proximal radius predominantly involving the dorsal aspect with large soft tissue component.The altered areas appear hypointense on T1 and hyperintense on T2 WIs. There is involvement of base of the third and the fourth ...
Source: Sumer's Radiology Site - February 8, 2022 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Is Anatomy Finished? | A Review of New Discoveries | TAPP 105
Are there reallyno more discoveries in human anatomy? In this episode, I'll review some recent discoveries: the rise of thefabella, macrophage barriers, the interstitium, button and zipper junctions, lymph node micro-organs, new vessels in bones, andtubarial salivary glands.00:00 | Introduction00:41 | Is Anatomy Finished?03:44 | Sponsored by AAA04:16 | Rise of the Fabella11:52 | Sponsored by HAPI12:38 | Macrophage Barriers23:18 | Sponsored by HAPS23:55 | Interstitium27:48 | Button and Zipper Junctions35:28 | Lymphatic Micro-Organ40:05 | Free Update Newsletter41:05 | New Vessels in Bones44:44 | Tubarial Salivary Glands...
Source: The A and P Professor - November 16, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs

A Handheld X-Ray System: Interview with Evan Ruff and Gregory Kolovich, Co-Founders of OXOS Medical
OXOS Medical, a medtech spin-off out of Georgia Tech, has created the Micro C, an FDA cleared handheld X-ray system that is designed to image the distal extremities, from the shoulder to the hand and from the knee to the foot. The device is intended to prevent situations in which clinicians have to handle and operate large machinery to perform simple X-ray imaging of small bones in the extremities, and allows them to conduct imaging right at the point of care. The device can be deployed during surgical procedures, and allows surgeons to more easily capture images that could be difficult to obtain using large, fixed equi...
Source: Medgadget - November 8, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Orthopedic Surgery Radiology Source Type: blogs

A Handheld X-Ray System: Interview with Evan Ruff and Gregory Kolovich, Co-Founders of OXOS Medical
OXOS Medical, a medtech spin-off out of Georgia Tech, has created the Micro C, an FDA cleared handheld X-ray system that is designed to image the distal extremities, from the shoulder to the hand and from the knee to the foot. The device is intended to prevent situations in which clinicians have to handle and operate large machinery to perform simple X-ray imaging of small bones in the extremities, and allows them to conduct imaging right at the point of care. The device can be deployed during surgical procedures, and allows surgeons to more easily capture images that could be difficult to obtain using large, fixed equi...
Source: Medgadget - November 8, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Orthopedic Surgery Radiology Source Type: blogs

Regulatory Capture
As you probably know, the FDA recently approved a monoclonal antibody called aducanumab as a treatment for Alzheimer ' s disease. To make a long story short, there ' s no good evidence that it actually has any effect on dementia; the approval is based on its effectiveness in removing abnormal plaques of a protein called beta-amyloid from the brain. These are associated with Alzheimer ' s disease, but there ' s no evidence that they cause it, or that removing them improves symptoms. Aducanumab can also have some very troubling adverse effects such as brain swelling. Oh yeah -- Biogen plans to charge $56,000/year for the tre...
Source: Stayin' Alive - September 17, 2021 Category: American Health Source Type: blogs

Fight Aging! Newsletter, August 30th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out mo...
Source: Fight Aging! - August 29, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Signs of Endothelial Inflammation in Human Neurodegeneration
Researchers here provide evidence from human blood samples that supports a role for vascular inflammation in age-related neurodegeneration. It is becoming clear that a great deal of tissue-specific information can be harvested from extracellular vesicles present in the bloodstream, if their contents were only better mapped and understood. The research community is still quite early in the process of establishing the necessary knowledge, but proof of concept demonstrations such as the study noted here are now emerging on a regular basis. Cerebrovascular disease and the associated blood-brain barrier (BBB) dysfuncti...
Source: Fight Aging! - August 26, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

We Need to Open Up the AI Black Box
To convince physicians and nurses that deep learning algorithms are worth using in everyday practice, developers need to explain how they work in plain clinical English.Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, and John Halamka, M.D., president, Mayo Clinic Platform, wrote this article.AI ’s so-called black box refers to the fact that much of the underlying technology behind machine learning-enhanced algorithms isprobability/statistics without a human readable explanation.Oftentimes that ’s the case because the advanced math or the data science behind the algorithms is t...
Source: Life as a Healthcare CIO - August 17, 2021 Category: Information Technology Source Type: blogs

Segmental approach to congenital heart disease
Segmental approach is used routinely in the echocardiographic evaluation of congenital heart disease. It is also useful in other cardiac imaging modalities used for evaluation of congenital heart disease like computed tomography and magnetic resonance imaging. Chest X-ray is useful in evaluating the cardiac position and visceral situs as it gives an overview of cardiac position in the thorax, position of left and right bronchi, aortic arch, liver and stomach air bubble [1]. Here is a chest X-ray in mesocardia with levo transposition of great arteries: X-ray chest PA showing mesocardia with L-TGA and L-posed aorta seen as ...
Source: Cardiophile MD - July 17, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Echocardiography Source Type: blogs

Does the FDA approval of aducanumab mark the return of science-based medicine?
The 20th century was an explosion of scientific innovation and discovery. The success of chemistry, physics and biology to produce things such as antibiotics, radiography and genetic analysis could not be ignored. Medicine is not now, nor has it ever been, a“science.” But over the past century, medicine became science-based. This means that whileRead more …Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 4, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/robert-trent" rel="tag" > Robert Trent < /a > < /span > Tags: Meds Medications Neurology Source Type: blogs

April 2021: ​Name that Fracture
Growing up in the ’70s, I loved the game show, “Name That Tune.” I was enthralled by the challenge of guessing the correct answer with the barest of clues. I marveled at the knowledge of those contestants who said they could name a tune in one note and who were proved right when the entire song was played. I wanted to have the expertise to say the answer with conviction before all was revealed.I never got that good with music, but I found a corollary in the emergency department in which I wished to excel. How many radiographs did I need to know where the fracture was? Could I know from subtle signs on just one view t...
Source: Lions and Tigers and Bears - April 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Evaluation of the Surgical Specimen After Neoadjuvant Systemic Therapy
ConclusionPostneoadjuvant systemic therapy histopathological changes are complex, and careful systematic review of the specimen is required for accurate diagnosis and follow-up treatment. For pathological complete response to be used as an indicator of response to novel therapies, it is essential to have a standardized way in which residual disease is measured and reported. We designed the recommendations specifically for the clinical trial setting; however, they can be optionally incorporated into routine practice because, in our opinion, standardization is most effective when uniformly applied. Hopefully, such standardiz...
Source: Oncopathology - March 23, 2021 Category: Cancer & Oncology Tags: breast Breast Biopsy Procedure breast cancer Source Type: blogs

March 2021: Injury Without Trauma
She was actively holding her arm against her side, her hand wrapping around her wrist. Any attempt to move her shoulder, actively or passively, brought an involuntary wince of pain. Tears quickly followed.My patient, a woman in her 40s, described increasing diffuse shoulder pain over two days. There was no trauma, but she described excruciating pain. She couldn't raise her arm at all, so I thought about a rotator cuff injury.She had had no injury, but rotator cuff tendons can give way to repetitive injury that thins the tissue until one day it just it breaks. It seemed more agony than this etiology would give. Maybe there ...
Source: Lions and Tigers and Bears - March 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs