Pfizer appeals $107m fine for anti-epilepsy drug prices in UK
Pfizer (NYSE:PFE) and Flynn Pharma have appealed the record $107 million (£84.2 million) and $6.5 million (£5.2 million) fines imposed by the U.K. Competition & Markets Authority in December for the companies’ massive price hikes to their unbranded versions of anti-epilepsy drug Epanutin.
In its appeal, Pfizer claims that the regulator did not consider market realities when it fined the drugmaker, saying “Pfizer challenges the CMA’s conclusion that it was dominant within the relevant market: the market for the manufacture of Pfizer-manufactured phenytoin sodium capsules that are distributed in the UK....
Source: Mass Device - February 15, 2017 Category: Medical Equipment Authors: Sarah Faulkner Tags: Legal News Pharmaceuticals Wall Street Beat Flynn Pharma Pfizer Source Type: news
A Quick Guide to Getting Enough Vitamin D
Shanna R. Levine, MD
Instructor of General Internal Medicine
The Mount Sinai Hospital
A Quick Guide to Getting Enough Vitamin D
If you are like many of my patients, you may be wondering, "Am I getting enough vitamin D?" This is a valid concern, because vitamin D plays a very important role in overall health and, in fact, many people do not get enough. The Centers for Disease Control and Prevention estimates that about one-third of Americans have insufficient levels. The good news is that sources of this vitamin are easily accessible.
Why Is Vitamin D Important?
Vitamin D helps the body absorb calcium from the gut, as w...
Source: Healthy Living - The Huffington Post - January 30, 2017 Category: Consumer Health News Source Type: news
UK slaps Pfizer with record $107m fine over price hikes
The Competition and Markets Authority reportedly fined Pfizer (NYSE:PFE) and Flynn Pharma a record amount for the companies’ massive price hikes to its unbranded versions of the anti-epilepsy drug, Epanutin. The British competition watchdog fined Pfizer and Flynn Pharma $107 million (£84.2 million) and $6.5 million (£5.2 million), respectively.
New York City-based Pfizer used to market the anti-epilepsy treatment as the branded drug Epanutin. The company sold the rights to Flynn in September 2012 and Flynn debranded the drug, removing it from the scrutiny of price regulation, and hiked the price of the phenyto...
Source: Mass Device - December 7, 2016 Category: Medical Equipment Authors: Sarah Faulkner Tags: Drug-Device Combinations Healthcare Reform Pharmaceuticals Regulatory/Compliance Wall Street Beat Flynn Pharma GlaxoSmithKline plc Pfizer Inc. Source Type: news
Phenytek Extended Release Capsule (Phenytoin Sodium) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 7, 2016 Category: Drugs & Pharmacology Source Type: news
UK's CMA fines Pfizer and Flynn Pharma nearly £ 90m for unfair pricing of epilepsy drug
Pfizer and Flynn Pharma have been fined nearly £ 90m by the Competition and Markets Authority (CMA) for charging unfair prices in the UK for phenytoin sodium capsules, an anti-epilepsy drug. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - December 7, 2016 Category: Pharmaceuticals Source Type: news
Dilantin Kapseals (Extended Phenytoin Sodium Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 28, 2016 Category: Drugs & Pharmacology Source Type: news
Dilantin Infatabs (Phenytoin Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 28, 2016 Category: Drugs & Pharmacology Source Type: news
Safety warning over incorrect use of injectable phenytoin
Clinicians have been warned about the risk of death and severe harm arising from the incorrect use of injectable phenytoin. (Source: Nursing Times)
Source: Nursing Times - November 9, 2016 Category: Nursing Source Type: news
phenytoin, Dilantin, Dilantin Infatabs, Phenytek, Phenytoin Infatabs
Title: phenytoin, Dilantin, Dilantin Infatabs, Phenytek, Phenytoin InfatabsCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/3/2016 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - November 3, 2016 Category: Drugs & Pharmacology Source Type: news
Human exposures to pentobarbital-phenytoin combination veterinary drugs - Forrester MB.
A combination of pentobarbital and phenytoin is used as a veterinary euthanasia drug. Because of its lethal effect, this study described pentobarbital-phenytoin combination veterinary drug human exposures reported to Texas poison centers during 2000-2015. ... (Source: SafetyLit)
Source: SafetyLit - September 12, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Dilantin 125 (Phenytoin Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 6, 2016 Category: Drugs & Pharmacology Source Type: news
New Evidence Backs Levetiracetam for Prolonged SeizureNew Evidence Backs Levetiracetam for Prolonged Seizure
Levetiracetam is as good as phenytoin for the treatment of status epilepticus, new data suggest, and might even be cheaper. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 25, 2016 Category: Consumer Health News Tags: Emergency Medicine News Source Type: news
Medical News Today: Nerve damage in MS could be prevented with epilepsy drug
An epilepsy drug - phenytoin - reduced nerve damage by 30% in people with optic neuritis, a new study found, bringing us closer to a neuroprotective drug for multiple sclerosis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 26, 2016 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news
Cheap epilepsy drug could prevent nerve damage in Multiple Sclerosis
The anti-seizure drug phenytoin was found to protect neural tissue in MS patients with optic neuritis, potentially preventing the onset of blindess (Source: Telegraph Health)
Source: Telegraph Health - January 25, 2016 Category: Consumer Health News Tags: drug cure treatment help multiple sclerosis epilepsy therapy Source Type: news
Definitive paper on phenytoin/phosphenytoin-associated purple glove syndrome
Purple glove syndrome (fda.gov)
4.5 out of 5 stars
Purple Glove Syndrome after Phenytoin or Fosphenytoin Administration: Review of Reported Cases and Recommendations for Prevention. Garbovsky LA et al. J Med Toxicol 2015 Dec;11:445-459.
Abstract
Purple glove syndrome (PGS) is an uncommon adverse drug reaction to parenteral administration of phenytoin or fosphenytoin marked by severe progressive soft tissue discoloration, swelling and pain in the distal extremity into which the drug was infused.
This extremely well done and comprehensive paper will tell you all you need to know (well, probably more than you need to know) ...
Source: The Poison Review - January 22, 2016 Category: Toxicology Authors: Leon Tags: Medical adverse drug reaction dilantin phenytoin phosphenytoin purple glove syndrome soft tissue Source Type: news
