Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Complex Penile Surgery: Plication, Grafting, and Implants
Urol Clin North Am. 2022 Aug;49(3):419-435. doi: 10.1016/j.ucl.2022.04.006. Epub 2022 Jun 30.ABSTRACTSurgical treatments for Peyronie's disease and erectile dysfunction are generally straightforward and associated with excellent outcomes. However, severe (>60°) and multidirectional curvature, hourglass deformity, severe penile shortening, and ossified plaque may complicate surgery in patients with Peyronie's disease. Similarly, a history of priapism, prior implant infection, and penile injury can pose challenges to successful implant surgery secondary to severe corporal fibrosis. Thus, when these pathophysiological pro...
Source: The Urologic Clinics of North America - August 5, 2022 Category: Urology & Nephrology Authors: Ziho Lee Jolie Shen Hunter Wessells Source Type: research

Impact of extracorporeal shockwave therapy for erectile dysfunction and peyronie's disease on reproductive and hormonal testicular function
Conclusion: ESWT in ED and PD patients does not seem to affect reproductive and hormonal testicular function.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - July 31, 2022 Category: Urology & Nephrology Authors: Celeste Manfredi, Davide Arcaniolo, Ugo Amicuzi, Lorenzo Spirito, Luigi Napolitano, Fabio Crocerossa, Marco Paoletta, Stefano Gisone, Paolo Cirillo, Felice Crocetto, Giuseppe Bellastella, Marco De Sio, Ciro Imbimbo Tags: ORIGINAL ARTICLE Source Type: research

Intratunical injection of rat-derived bone marrow mesenchymal stem cells prevents fibrosis and is associated with increased Smad7 expression in a rat model of Peyronie's disease
CONCLUSIONS: The antifibrotic effects of BMSCs treatment in the active phase of the PD rat model were better than those in the chronic phase. A possible mechanism of BMSCs treatment was related to increased Smad7 expression, suggesting a possible effective and safe procedure for the treatment of PD.PMID:35908015 | DOI:10.1186/s13287-022-03090-w (Source: Cell Research)
Source: Cell Research - July 30, 2022 Category: Cytology Authors: Wenting Wang Weifang Ding Xuebao Zhang Shuang Wu Tianxi Yu Xin Cui Yaqi Xie Diandong Yang Chunhua Lin Source Type: research

Tolerance and efficacy of platelet-rich plasma injections in Peyronie's disease: Pilot study
CONCLUSION: Our initial experience suggests that PRP injections for Peyronie's disease are safe. Although the limited data is suggestive of efficacy, a placebo control will be required for confirmation.PMID:35778315 | DOI:10.1016/j.purol.2022.05.004 (Source: Progres en Urologie)
Source: Progres en Urologie - July 1, 2022 Category: Urology & Nephrology Authors: A Schirmann E Boutin A Faix R Yiou Source Type: research