Do proton pump inhibitors cause heart attacks?
This study used a technique called “data-mining” to extract information from years of electronic medical records (EMRs) and included about 70 thousand patients in their primary analysis. They describe the data-mining technique in the article, which seems to boil down to assigning a mathematical function to certain defined variables (patients taking PPIs) and an outcome (heart attack) to see if the two events are associated.
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Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 18, 2015 Category: Journals (General) Authors: Frederick Gandolfo, MD Tags: Meds GI Heart Source Type: blogs
Stomach Pain: It Continues – Part II
Part I can be found by clicking here: Stomach Pain: It Starts – Part I.
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We sat quietly waiting in the waiting room. Again, we found ourselves in an odd position of being on the patient end of things. Allison, my wife, is a registered nurse. At the time she was working as an RN on a cardiac unit and I was at the end of my second year of Internal Medicine residency. Also, before this GI appointment, Allison had made a 2nd visit to the LLUMC ED. On that second visit they had decided to admit her to the Family Medicine service since her primary doctor was from the Family Medicine service. They did what they could but ...
Source: JeffreyMD.com - February 23, 2015 Category: Internal Medicine Authors: Dr. Jeff Tags: My Life abdominal pain EGD esophagogastroduodenoscopy gastroenterology HIDA scan stomach pain thewife Source Type: blogs
Tissue Engineering of Small Stomachs for Research
The first stage of success in tissue engineering of any specific organ is to produce small sections of tissue that are close enough to the real thing to be used in research. Given a methodology to reliably produce these tissue sections from the starting point of a cell sample, they can be used in drug testing, to investigate the detail mechanisms of genetic diseases and aging, and similar applications. It is also possible that even small amounts of tissue can be the basis for some treatments, as patches for localized injuries that are resistant to regeneration:
Three-dimensional "mini-stomachs" have been created from huma...
Source: Fight Aging! - October 30, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Laboratory Abnormalities and Pyloric Stenosis
The classic clinical presentation of infantile hypertrophic pyloric stenosis (IHPS) is an emaciated 3- to 6-week-old infant who has been experiencing immediate postprandial, nonbilious, projectile vomiting over a period of weeks. The infants remain hungry and demand to be re-fed after vomiting. Caucasian, full-term boys (4:1 to 6:1) tend to present with this condition most frequently, and these patients tend to be firstborns.
An olive-sized tumor can be felt to the right of the umbilicus, and this may best be palpable immediately after the infant has vomited. Visible peristaltic waves may also be noted. The infants are ty...
Source: M2E Too! Mellick's Multimedia EduBlog - February 28, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Laboratory Abnormalities and Pyloric Stenosis
The classic clinical presentation of infantile hypertrophic pyloric stenosis (IHPS) is an emaciated 3- to 6-week-old infant who has been experiencing immediate postprandial, nonbilious, projectile vomiting over a period of weeks. The infants remain hungry and demand to be re-fed after vomiting. Caucasian, full-term boys (4:1 to 6:1) tend to present with this condition most frequently, and these patients tend to be firstborns.
An olive-sized tumor can be felt to the right of the umbilicus, and this may best be palpable immediately after the infant has vomited. Visible peristaltic waves may also be noted. The infants are typ...
Source: M2E Too! Mellick's Multimedia EduBlog - February 28, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
An acerbic opinion versus a sweet solution towards chronic pain
CONCLUSION: Glucose sublingual is and effective analgesic in infants between 1 and 12 months of age Barry E. Levin,1,2 Vanessa H. Routh,3 Ling Kang,2 Nicole M. Sanders,4 and Ambrose A. Dunn-Meynell1,2. Neuronal Glucosensing. What Do We Know After 50 Years? DIABETES, VOL. 53, OCTOBER 2004 Min-tsai Liu1, 2, Susumu Seino3, and Annette L. Kirchgessner1, 2 Identification and Characterization of Glucoresponsive Neurons in the Enteric Nervous System. The Journal of Neuroscience, December 1, 1999, 19(23):10305-10317 J. Antonio Gonzàlez1, Frank Reimann2 and Denis Burdakov1.Dissociation between sensing and metabolism of glucose in ...
Source: HealthSkills Weblog - February 16, 2014 Category: Occupational Therapists Authors: adiemusfree Tags: Pain conditions Professional topics Therapeutic approaches Chronic pain healthcare Source Type: blogs
BreathID Hp Non-Invasively Test Spots H. Pylori in Exhaled Breath
It took Nobel Prize-winning scientific work to make the bacteria Helicobacter pylori famous. Able to survive in the highly acidic environment of the stomach, it has been found to be the common cause of many peptic ulcers, so detecting its presence can help prevent and treat a disease that affects approximately 4.5 million people in the United States annually.
We’ve been following the BreathID device from Exalenz Bioscience for a few years now (flashbacks below) as it’s been going through clinical trials, and now the company is reporting that its BreathID Hp test for H. pylori is now being made available globall...
Source: Medgadget - July 31, 2013 Category: Technology Consultants Authors: Editors Tags: GI Pathology Source Type: blogs
Gastritis + Cervical spondylosis = Classical Angina
Spinal cord is a busy neurological highway to brain .It runs 24/7 non stop with unlimited horizontal and vertical lanes .It is such a compact structure , it can easily get confounded when multiple signals converge, diverge, summate , deduct , reflect back, or cancel out .
A 64 year old women came to me for second opinion regarding chest pain . A cardiologist had just adviced her an emergency coronary angiogram and also suggested she may require an urgent PCI as well .
I listened to her history in my office . . . In her own words .
Doctor , I am getting...
Source: Dr.S.Venkatesan MD - June 27, 2013 Category: Cardiology Authors: dr s venkatesan Tags: cardaic physiology cardiac physiology Cardiology - Clinical Clinical cardiology atypical chest pain angina classical angina differential diagnosis for chest pain gastrits and cervical spondylosis equals angian Source Type: blogs
Too Many Scopes
Colonoscopy is overdone in this country. This is an observable fact. I see patients every single day who get scoped every 2-3 years for no discernible reason. I see inpatient 90 year olds who present with "GI bleed" (really just a little coffee ground emesis from dehydration/mild peptic ulcer disease) who end up getting black tubes snaked through their mouth and anus before they are returned to the nursing home from whence they came. This happens constantly. A study from Archives of Internal Medicine elucidates this phenomenon:
The colonoscopists with percentages significantly above...
Source: Buckeye Surgeon - March 18, 2013 Category: Surgeons Authors: Jeffrey Parks MD Source Type: blogs
Too Many Scopes
Colonoscopy is overdone in this country. This is an observable fact. I see patients every single day who get scoped every 2-3 years for no discernible reason. I see inpatient 90 year olds who present with "GI bleed" (really just a little coffee ground emesis from dehydration/mild peptic ulcer disease) who end up getting black tubes snaked through their mouth and anus before they are returned to the nursing home from whence they came. This happens constantly. Astudy from Archives of Internal Medicine elucidates this phenomenon:The colonoscopists with percentages significantly above th...
Source: Buckeye Surgeon - March 17, 2013 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs
Cardiac Outcomes
Alice Park reviews David Jones' counter intuitive new book on the history of cardiac surgery and coronary angioplasty in most recent issue of Harvard magazine. Jones, also a physician, is a professor of medical history at Harvard. His latest book explores the rise of interventional cardiology and cardiac surgery since the 60's and how much of the rationale for such a procedure-dominated treatment strategy is undergirded by some surprisingly shoddy data.
The first randomized clinical trial of bypass surgery’s efficacy, using data from a collaboration of Veterans Administration hospitals, was ...
Source: Buckeye Surgeon - March 13, 2013 Category: Surgeons Authors: Jeffrey Parks MD Source Type: blogs
Cardiac Outcomes
Alice Parkreviews David Jones' counter intuitive newbook on the history of cardiac surgery and coronary angioplasty in most recent issue of Harvard magazine. Jones, also a physician, is a professor of medical history at Harvard. His latest book explores the rise of interventional cardiology and cardiac surgery since the 60's and how much of the rationale for such a procedure-dominated treatment strategy is undergirded by some surprisingly shoddy data. The first randomized clinical trial of bypass surgery ’s efficacy, using data from a collaboration of Veterans Administration hospitals, was not ...
Source: Buckeye Surgeon - March 12, 2013 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs
Peptic Ulcer Disease
Pathophysiology of Peptic Ulcer Disease
1) peptic ulcer disease is marked by a break in mucosal lining of stomach and duodenum
2) main causes are infection with Helicobacter pylori and use of NSAIDs
Signs and Symptoms
1) burning epigastric pain relieved by antacids and eating
2) epigastric pain causing patient to wake up in the middle of the night
3) chest pain mimicking angina
4) epigastric tenderness
5) gastrointestinal bleeding (15%) with coffee-ground emesis or vomiting bright red blood or lower gastrointestinal bleeding
6) perforation (8%) with peritonitis and rigid abdomen
7) duodenal obstruction (3%) with nausea and...
Source: Inside Surgery - February 24, 2013 Category: Surgeons Authors: Editor Tags: Gastroenterology Source Type: blogs
USMLE Questions – Characteristic Disease Findings
The United States Medical Licensing Examination (USMLE) is designed to emphasize knowledge of clinical scenarios and clinical pearls, even on Step I. Listed below are some commonly encountered disease findings and characteristics.
Feature
Disease
45, X chromosome
Turner’s syndrome
5-HIAA increased in urine
Carcinoid syndrome
Aganglionic rectum
Hirschsrpung’s disease
Apple-core sign on barium enema
Colon cancer
Arched back (opisthotonos)
Tetanus
Argyll-Robertson pupil
Syphilis
Ash leaf on forehead
Tuberous sclerosis
Auer rods
Acute myelogenous leukemia
Austin Flint murmur
Aortic regurgitation...
Source: Inside Surgery - January 18, 2013 Category: Surgeons Authors: Editor Tags: Surgpedia USMLE diseases findings VMA water hammer pulse Source Type: blogs
