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Over Transfused
A new paper from NEJM indicates that perhaps we need to re-calibrate our blood transfusion strategies in patients with severe upper gastrointestinal bleeds.  Patients were randomly assigned to liberal (transfuse for HgB under 9) vs restrictive (transfuse only for HgB under 7) transfusion treatment protocols and outcomes were measured (survival, bleeding, portal venous gradients, etc).  The probability of survival was slightly higher with the restrictive strategy than with the liberal strategy in the subgroup of patients who had bleeding associated with a peptic ulcer (hazard ratio, 0.70; 95% CI, ...
Source: Buckeye Surgeon - January 8, 2013 Category: Surgeons Authors: Jeffrey Parks MD Source Type: blogs