Allogeneic stem cell transplantation and CAR-T in B-cell Non-Hodgkin Lymphoma: a two-center experience and review of the literature
The objective of this study was to analyze long-term outcomes of patients with B-NHL who received allo-HSCT. We analyzed overall survival (OS), progression-free survival (PFS) and graft versus host disease (GVHD) relapse-free survival (GRFS) in 53 patients undergoing allo-HSCT from two institutions. The median follow-up of the study was 72 months (range 29–115 months). The median number of lines of therapy before allo-HSCT was 3 (range 1–6) and twenty-eight patients (53%) had received a previous autologous transplant. The 3-year PFS, OS and GRFS were 55%, 63%, and 55%, respectively. One-year non-relapse mortality wa...
Source: Annals of Hematology - March 2, 2024 Category: Hematology Source Type: research
‘A tough experience.’ Why would a scientist serve as an expert witness?
Late last year, the sound of scientific argument echoed through a New York City courtroom packed with legal and financial experts. Studies from top epidemiology journals flashed onto large screens, as lawyers debated their statistical power and whether their conclusions rested on “cherry-picked” data.
Billions of dollars were at stake.
The scientists themselves were absent, and attorneys argued on their behalf. But the crucial issue was whether some of the scientists would be allowed to appear at a future trial, where they would tell jurors that children had developed autism or attention-deficit/hyperactivi...
Source: Science of Aging Knowledge Environment - February 29, 2024 Category: Geriatrics Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Collection efficiency and safety of large-volume leukapheresis for the manufacturing of tisagenlecleucel
CONCLUSION: LVL procedures using Spectra Optia cMNC protocol was well tolerated and did not affect the manufacturing of tisa-cel.PMID:38419458 | DOI:10.1111/trf.17765 (Source: Transfusion)
Source: Transfusion - February 29, 2024 Category: Hematology Authors: Wataru Kitamura Tomohiro Urata Keiko Fujii Takuya Fukumi Kazuhiro Ikeuchi Keisuke Seike Hideaki Fujiwara Noboru Asada Daisuke Ennishi Ken-Ichi Matsuoka Fumio Otsuka Yoshinobu Maeda Nobuharu Fujii Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Collection efficiency and safety of large-volume leukapheresis for the manufacturing of tisagenlecleucel
CONCLUSION: LVL procedures using Spectra Optia cMNC protocol was well tolerated and did not affect the manufacturing of tisa-cel.PMID:38419458 | DOI:10.1111/trf.17765 (Source: Transfusion)
Source: Transfusion - February 29, 2024 Category: Hematology Authors: Wataru Kitamura Tomohiro Urata Keiko Fujii Takuya Fukumi Kazuhiro Ikeuchi Keisuke Seike Hideaki Fujiwara Noboru Asada Daisuke Ennishi Ken-Ichi Matsuoka Fumio Otsuka Yoshinobu Maeda Nobuharu Fujii Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma
This report, which includes a summary of each presentation, reviews the findings presented at the workshop and highlights opportunities, open questions, and areas for future study that would pave the way for a cure for this disease in the coming decades.PMID:38421601 | DOI:10.46883/2024.25921013 (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - February 29, 2024 Category: Cancer & Oncology Authors: Lymphoma Research Foundation Lymphoma Research Foundation Source Type: research
