The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
The coexistence of two rare diseases thought to use the same pathologic pathway: cystic fibrosis and Niemann-Pick disease
CONCLUSIONS: Although CF and NP have common systems of involvement in both diseases, pathological symptoms have different origins. If a patient with CF has simultaneous neuromotor delay, other autosomal recessive diseases that may accompany it should be suspected. In studies, similar pathological pathways related to abnormal cholesterol accumulation in the cell were detected between NP type C and CF. But our case was NPA. As case reports on the coexistence of the two diseases increase, we believe that a better understanding of similar pathological pathways may lead to new therapeutic targets for both diseases.PMID:36583901...
Source: The Turkish Journal of Pediatrics - December 30, 2022 Category: Pediatrics Authors: Asl ı İmran Yılmaz Bet ül Uğurlu G ökçen Ünal H üseyin Tokgöz Sevgi Pekcan Source Type: research
