Notice of Intent to Publish a Funding Opportunity Announcement for Understanding Neurological Effects of COVID-19 and Post-Acute Sequelae of SARS-CoV-2 Infection (R21 Clinical Trial Optional)
Notice NOT-NS-23-069 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2023 Category: Research Source Type: funding

Take Advantage of Our Many Resources for Enhancing the Rigor of Animal Research
“Despite the numerous successes stemming from animal research, concerning reports over the past decade have described biomedical experiments that fail to replicate or to translate in ways that improve human health. All research is not expected to translate to human treatments, as there is no perfect model. Scientific process is as much about failure as it is about success. Yet part of the scientific process is also continual improvement, which includes working to understand what might contribute to unexpected outcomes within animal research.” The Advisory Committee to the NIH Director (ACD) expressed that view in their...
Source: NIH Extramural Nexus - February 10, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Alternatives to Animals reproducibility rigor Source Type: funding

Using Multimodal Biomarkers to Differentially Diagnose ADRDs for Clinical Trials (U19 Clinical Trial Optional)
Funding Opportunity RFA-NS-24-001 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to enable multi-site clinical validation of a multimodal set of neuroimaging and biospecimen biomarkers to differentially diagnosis three or more similarly presenting neurodegenerative diseases, including at least one of the Alzheimers Disease and Related Dementias (ADRDs). As part of the program deliverables, investigators will be required to work towards qualifying the candidate biomarkers as therapeutic/drug development tools through the FDAs Biomarker Qualification Program. *Note this FOA has cha...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 9, 2023 Category: Research Source Type: funding

Education Activities for Responsible Analyses of Complex, Large-Scale Data (R25- Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-24-027 from the NIH Guide for Grants and Contracts. This concept proposes to advance methodological rigor in NIDA-relevant research by supporting training on the responsible analyses of complex, large-scale datasets involving brain, behavioral, genomic, and socioenvironmental data through: 1. Courses for Skills Development 2. Curriculum or Methods Development (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2023 Category: Research Source Type: funding

Notice of Early Expiration of NINDS BRAIN Initiative Funding Opportunity Announcements (FOA) RFA-NS-21-026 and RFA-NS-21-027
Notice NOT-NS-23-037 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2023 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Notice NOT-NS-23-036 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2023 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
Notice NOT-NS-23-035 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2023 Category: Research Source Type: funding

NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Funding Opportunity PAR-23-090 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementatio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2023 Category: Research Source Type: funding

Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional)
Funding Opportunity RFA-DA-24-037 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to incre...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 7, 2023 Category: Research Source Type: funding

Data Harmonization, Curation and Secondary Analysis of Existing Clinical Datasets (R61/R33 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-089 from the NIH Guide for Grants and Contracts. This FOA invites applications from multidisciplinary teams to perform secondary data analysis, using existing datasets from two or more multi-site clinical research projects, to address scientific and clinical hypotheses relevant to neurological disorders and conditions within the NINDS mission. In this phased funding mechanism, applications are required to systematically and comprehensively perform cross-project data harmonization and curation, assessed using Go/No-go data-quality metrics, prior to funding of the second phase of data analyses. ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 31, 2023 Category: Research Source Type: funding

Team Science Approaches Integrating Experimental and Computational Brain Aging Models (R21/R33 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-24-018 from the NIH Guide for Grants and Contracts. This FOA invites applications proposing to establish new, or significantly expand existing, interdisciplinary collaborations involving both experimental and computational researchers to simultaneously address a targeted research question in brain aging and Alzheimer's disease (AD),including Alzheimer's disease related dementias (ADRD). This FOA will use the R21/R33 to provide up to 2 years of R21 support for initial developmental activities and up to 3 years of R33 support for expanded activities. Through this award, investigators will develo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 31, 2023 Category: Research Source Type: funding

Notice of Special Interest (NOSI) for Administrative Supplements: Harmonization and Joint Analysis of Human Brain Single-Cell Datasets
Notice NOT-NS-23-042 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 30, 2023 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for A Consortium for Gut-Brain Communication in Parkinsons Disease (U24 Clinical Trial Not Allowed)
Notice NOT-DK-23-007 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 24, 2023 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for A Consortium for Gut-Brain Communication in Parkinsons Disease (U01 Clinical Trial Not Allowed)
Notice NOT-DK-23-006 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 24, 2023 Category: Research Source Type: funding

Novel Assays to Address Translational Gaps in Treatment Development (UG3/UH3 Clinical Trial Optional)
Funding Opportunity PAR-23-087 from the NIH Guide for Grants and Contracts. The overall goal of this initiative is to identify neurophysiological measures potential assays for treatment development research. The funding opportunity announcement (FOA) will support efforts to optimize and evaluate measures of neurophysiological processes that are disrupted within or across mental disorders in both healthy humans and in another species relevant to the therapeutic development pipeline. The initiative will support initial proof of concept studies aimed at identifying measures for potential development as preclinical assays f...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 13, 2023 Category: Research Source Type: funding