Neoadjuvant PSMA-RLT in Oligometastatic PCa
Conditions: Prostate Cancer Interventions: Drug: [177Lu]Lu-PSMA I&T Sponsors: Medical University of Vienna Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

NEOadjuvant Abemaciclib and GIredestrant triaL in Patients With ER-positive, HER2-negative Early Breast Cancer
Conditions: Breast Cancer Interventions: Drug: Abemaciclib 150 MG + Giredestrant 30 MG Sponsors: Fondazione Oncotech Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

Neoadjuvant Therapy With Toripalimab and JS004 Combined With Etoposide and Platinum Chemotherapy for Limited-stage Small Cell Lung Cancer : A Phase 2 Trial
Conditions: Limited Stage Small Cell Lung Cancer Interventions: Drug: JS004; Drug: Toripalimab; Procedure: surgery; Drug: Etoposide; Drug: Platinum Sponsors: Shanghai Pulmonary Hospital, Shanghai, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 13, 2024 Category: Research Source Type: clinical trials

The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer
Conditions: Rectal Cancer; Rectal Cancer Stage II; Rectal Cancer Stage III Interventions: Drug: Tislelizumab combined with chemotherapy Sponsors: First Affiliated Hospital of Guangxi Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials

Neoadjuvant Sintilimab Plus Chemoradiotherapy for Locally Advanced Adenocarcinoma of Esophagogastric Junction
Conditions: PD-1; Neoadjuvant Chemoradiotherapy; Gastroesophageal Junction Cancer Interventions: Drug: PD-1inhibitor Sponsors: Wuhan Union Hospital, China Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

Study for Wait and Watch Suitable for Rectal Cancer
Conditions: Rectal Neoplasms Interventions: Other: Short Course radiotherapy based total neoadjuvant treatment +/- brachytherapy boost dose Sponsors: Tata Memorial Centre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

MRI Guided SIB Radiotherapy in Neoadjuvant Therapy for Advanced Rectal Cancer
Conditions: Rectal Cancer Interventions: Radiation: MRI Guided Simultaneous Integrated Boost Radiotherapy Sponsors: Shandong Cancer Hospital and Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC
Conditions: Triple Negative Breast Cancer Interventions: Drug: Paclitaxel; Drug: Carboplatin; Drug: Pembrolizumab; Drug: Doxorubicin; Drug: Cyclophosphamide; Drug: Olaparib; Drug: Capecitabine Sponsors: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

Efficacy and Safety of NSCLC Patients With/Without Adjuvant Immunotherapy Who Have Achieved pCR After Neoadjuvant Immunotherapy
Conditions: Resectable/Potentially Resectable NSCLC Interventions: Drug: Immunotherapy Sponsors: Xiangya Hospital of Central South University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 6, 2024 Category: Research Source Type: clinical trials

Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma Interventions: Other: non-intervention Sponsors: Tianjin Medical University Cancer Institute and Hospital; Chinese Academy of Medical Sciences; Sichuan Cancer Hospital and Research Institute Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2024 Category: Research Source Type: clinical trials

Neoadjuvant Camrelizumab Combined With Chemotherapy for Resectable Stage IIIA-IIIB NSCLC
Conditions: IMMUNOTHERAPY; Neoadjuvant Therapy; Resectable Lung Non-Small Cell Carcinoma; Biomarkers / Blood Interventions: Drug: Camrelizumab Plus Chemotherapy Sponsors: Shandong Cancer Hospital and Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2024 Category: Research Source Type: clinical trials

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
Conditions: Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer Interventions: Drug: Envafolimab combined with chemoradiotherapy in the whole course of neoadjuvant therapy Sponsors: Yunnan Cancer Hospital; Beijing Bethune Charitable Foundation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2024 Category: Research Source Type: clinical trials

Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma
Conditions: Head and Neck Squamous Cell Carcinomas; Resectable Head and Neck Squamous-cell Carcinoma Interventions: Drug: Tislelizumab; Drug: Nab-paclitaxel; Drug: Carboplatin Sponsors: Xiang Lu Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials

Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC
Conditions: Recurrent Nasopharyngeal Carcinoma Interventions: Procedure: endoscopic surgery; Drug: Neoadjuvant therapy,Toripalimab Injection and Gemcitabine based therapy; Drug: Adjuvant therapy in experimental group,Toripalimab Injection and Gemcitabine based therapy; Drug: Adjuvant therapy in control group,Toripalimab Injection and Gemcitabine based therapy Sponsors: Eye& ENT Hospital of Fudan University; Shanghai Zhongshan Hospital; Shanghai 6th People ' s Hospital; Changhai Hospital; Fujian Medical University Union Hospital; People ' s Hospital of Guangxi; Shenzhen Second People ' s Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials

Comparing Astragalus Plus Gemcitabine to Gemcitabine Alone as Neoadjuvant Treatment for Pancreatic Cancer Patients
Conditions: Pancreatic Cancer Interventions: Drug: Astragalus + Gemcitabine; Drug: Gemcitabine alone Sponsors: Shenzhen University General Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials