A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
Conditions: Breast Cancer Interventions: Drug: Dato-DXd; Drug: Durvalumab; Drug: Pembrolizumab; Drug: Doxorubicin; Drug: Epirubicin; Drug: Cyclophosphamide; Drug: Paclitaxel; Drug: Carboplatin; Drug: Capecitabine; Drug: Olaparib Sponsors: AstraZeneca; Daiichi Sankyo, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 1, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Camrelizumab With Dalpiciclib for Resectable Esophageal or Head and Neck Squamous Cell Carcinomas
Conditions: Esophageal Squamous Cell Carcinoma; Head and Neck Squamous Cell Carcinoma Interventions: Drug: Camrelizumab; Drug: Dalpiciclib 100mg; Drug: Dalpiciclib 150mg Sponsors: West China Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials

Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody in Preoperative Neoadjuvant Therapy for MSS Locally Advanced Rectal Cancer - a Multicenter, Single-arm, Open-label Clinical Trail
Conditions: MSS Locally Advanced Rectal Cancer Interventions: Drug: Sintilimab with Interleukin-2 Sponsors: The First Affiliated Hospital with Nanjing Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Chemotherapy for Obstructive Colon cancER First Treated by cOlostomy
Conditions: Colon Cancer Interventions: Drug: Neoadjuvant chemotherapy Sponsors: University Hospital, Rouen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials

Dalpiciclib Plus AI (Neoadjuvant Endocrine Therapy) Compared With Neoadjuvant Chemotherapy in Early Breast Cancer (EBC)
Conditions: Breast Cancer Interventions: Drug: Dalpiciclib; Drug: Aromatase inhibitor; Drug: Docetaxel injection; Drug: Epirubicin Hydrochloride Injection; Drug: Cyclophosphamide injection Sponsors: Hebei Medical University Fourth Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials

Dynamic ctDNA Monitoring in Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma Sponsors: Hebei Medical University Fourth Hospital; Handan Central Hospital; Xingtai People ' s Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 27, 2023 Category: Research Source Type: clinical trials

Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC
Conditions: Head and Neck Squamous Cell Carcinoma; Neoadjuvant Therapy; Pembrolizumab Interventions: Drug: Pembrolizumab; Drug: Cisplatin; Drug: Carboplatin; Drug: Nedaplatin; Drug: Nab paclitaxel; Drug: Docetaxel; Drug: Liposomal paclitaxel; Drug: Fluorouracil Sponsors: Beijing Tongren Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

Total Neoadjuvant Treatment for pMMR Locally Advanced Low Rectal Cancer: Anti-PD-1 Antibody With FOLFOXIRI and Preoperative Radiation Therapy
Conditions: Colorectal Cancer Interventions: Drug: Serplulimab + FOLFOXIRI; Radiation: Radiation therapy Sponsors: Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 25, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer
Conditions: Rectal Cancer Interventions: Drug: Neoadjuvant Chemoradiotherapy; Drug: Total Neoadjuvant Therapy Sponsors: St. James ' s Hospital, Ireland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 24, 2023 Category: Research Source Type: clinical trials

Axillary Management After Neoadjuvant Chemotherapy
Conditions: Breast Cancer; Breast Neoplasms; Breast Cancer Female Interventions: Procedure: Axillary sentinal lymph node biopsy Sponsors: Medipol University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Adebrelimab Plus Etoposide and Cisplatin in Neuroendocrine Bladder Carcinoma
Conditions: Neuroendocrine Carcinoma of the Bladder; Bladder Cancer Interventions: Drug: Adebrelimab; Drug: Etoposide; Drug: Cisplatin; Procedure: Radical Cystectomy Sponsors: RenJi Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 19, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLC
Conditions: Non-Small Cell Lung Cancer Interventions: Biological: Dupilumab; Biological: Cemiplimab Sponsors: Icahn School of Medicine at Mount Sinai Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 18, 2023 Category: Research Source Type: clinical trials

Investigate the Prognostic and Predictive Value of ctDNA During Neoadjuvant Chemotherapy for Breast Cancer.
Conditions: Breast Cancer Female; Stage II Breast Cancer; Stage III Breast Cancer; HER2-positive Breast Cancer; Triple Negative Breast Cancer Sponsors: Gene Solutions Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials

Sentinel lympH Node Biopsy With Indocyanine Green in Breast Cancer After NEoadjuvant Chemotherapy (SHINE)
Conditions: Breast Cancer Interventions: Procedure: ICG guided sentinel lymph node biopsy Sponsors: University Health Network, Toronto Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials

Penpulimab Combined With Chemotherapy for Neoadjuvant and Adjuvant Therapy in Patients With Resectable HNSCC
Conditions: Head and Neck Squamous Cell Carcinoma Interventions: Drug: Penpulimab injection; Drug: cisplatin; Drug: albumin-paclitaxel Sponsors: Shanghai Ninth People ' s Hospital Affiliated to Shanghai Jiao Tong University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 13, 2023 Category: Research Source Type: clinical trials